Malpighian tubule Type II cell [FBbt_00005797]

Morphologically distinct cell type found only in the initial, transitional and main segments of the Malpighian tubules interspersed with Type I cells. Type II cells are smaller and flatter than Type I cells, with shorter (main segment) or no (initial region) apical microvilli. Type II cells originate from a subset of caudal visceral mesoderm cells that overlie the tubule primordia as they evert from the hindgut. By stage 15, Type II cells have been incorporated in the tubules and adopt epithelial characteristics. In the mature tubules there are on average 110 Type II cells.

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Malpighian tubule Type II cell

ID: FBbt_00005797

Cell

Morphologically distinct cell type found only in the initial, transitional and main segments of the Malpighian tubules interspersed with Type I cells. Type II cells are smaller and flatter than Type I cells, with shorter (main segment) or no (initial region) apical microvilli. Type II cells originate from a subset of caudal visceral mesoderm cells that overlie the tubule primordia as they evert from the hindgut. By stage 15, Type II cells have been incorporated in the tubules and adopt epithelial characteristics. In the mature tubules there are on average 110 Type II cells.

These cells are involved in primary urine production via the presence of ion channels that allow chloride and water to enter the tubule lumen (O'Donnell et al., 1998).

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## Classification

Relationships

develops from: Malpighian tubule Type II cell primordium

Alternative Names

Synonym	Scope	Reference
SC	exact synonym
Malpighian tubule stellate cell	exact synonym	Wessing and Eichelberg, 1978
excretory star cell	exact synonym

Subclasses of Malpighian tubule Type II cell (7 total)

Thumbnail	Name	Tags
	adult Malpighian tubule Type II cell	Adult, Cell
	adult Malpighian tubule bar-shaped cell of initial segment	Adult, Cell
	adult Malpighian tubule bar-shaped cell of transitional segment	Adult, Cell
	embryonic Malpighian tubule Type II cell	Cell
	embryonic/larval Malpighian tubule Type II cell	Cell, Larva

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Expression patterns overlapping Malpighian tubule Type II cell (5 total)

Thumbnail	Name	Tags
	P{hbs-lacZ.4} expression pattern	Expression_pattern
	P{GawB}tsh[c724] expression pattern	Expression_pattern
	P{GawB}c649 expression pattern	Expression_pattern
	P{GawB}c710 expression pattern	Expression_pattern
	P{PZ}tsh[04319] expression pattern	Expression_pattern

View all 5 results in VFB →

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n style="color:#f1fa8c">"has_exact_synonym", "label": "SC", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "excretory star cell", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_exact_synonym", "label": "Malpighian tubule stellate cell", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/FBrf0030988", "types": [ "Entity", "Individual", "pub" ], "short_form": "FBrf0030988", "label": "Wessing and Eichelberg, 1978, Ashburner, Wright, 1978-1980 c: 1--42" }, "FlyBase": "", "PubMed": "", "DOI": "" } } ], "def_pubs": [ { "core": { "symbol": "", "iri": "http://flybase.org/reports/FBrf0222532", "types": [ "Entity", "Individual", "pub" ], "short_form": "FBrf0222532", "label": "Denholm, 2013, Organogenesis 9(1): 40--54" }, "FlyBase": "", "PubMed": "23445869", "DOI": "10.4161/org.24107" }, { "core": { "symbol": "", "iri": "http://flybase.org/reports/FBrf0160477", "types": [ "Entity", "Individual", "pub" ], "short_form": "FBrf0160477", "label": "Denholm et al., 2003, Curr. Biol. 13(12): 1052--1057" }, "FlyBase": "", "PubMed": "12814552", "DOI": "10.1016/S0960-9822(03)00375-0" }, { "core": { "symbol": "", "iri": "http://flybase.org/reports/FBrf0102373", "types": [ "Entity", "Individual", "pub" ], "short_form": "FBrf0102373", "label": "O'Donnell et al., 1998, Am. J. Physiol. R., Regul. Integr. Comp. Physiol. 274(4 Pt. 2): R1039--R1049" }, "FlyBase": "", "PubMed": "9575967", "DOI": "" }, { "core": { "symbol": "", "iri": "http://flybase.org/reports/FBrf0064792", "types": [ "Entity", "Individual", "pub" ], "short_form": "FBrf0064792", "label": "Skaer, 1993, Bate, Martinez Arias, 1993: 941--1012" }, "FlyBase": "", "PubMed": "", "DOI": "" } ] }

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