adult EBa1 lineage clone [FBbt_00050137]
A clone of neurons in the adult brain, all of which develop from neuroblast EBa1.
A clone of neurons in the adult brain, all of which develop from neuroblast EBa1.
Any neuron (FBbt:00005106) that is part of some adult (FBbt:00003004) and develops from some neuroblast DALv2 (FBbt:00050136).
Adult brain-intrinsic neuron of the ATL009 group, with its soma in the brain, anterior to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral antler, the ipsilateral crepine, the ipsilateral superior medial protocerebrum and the ipsilateral inferior bridge (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 9 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the ATL010 group, with its soma in the brain, anterior to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral superior medial protocerebrum, the ipsilateral antler, the ipsilateral crepine and the ipsilateral superior clamp (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine, the ipsilateral lateral accessory lobe and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 5 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB1079 group, with its soma in the brain, anterior to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral superior medial protocerebrum, the ipsilateral crepine and the ipsilateral superior intermediate protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). There are approximately 18 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB1124 group, with its soma in the brain, anterior to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral superior intermediate protocerebrum, the ipsilateral superior medial protocerebrum and the ipsilateral crepine (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral superior intermediate protocerebrum, the ipsilateral crepine, the contralateral superior intermediate protocerebrum, the ipsilateral superior medial protocerebrum and the contralateral crepine (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 4 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB1128 group, with its soma in the brain, anterior-lateral to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine and the ipsilateral mushroom body medial lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). There are approximately 3 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB1454 group, with its soma in the brain, anterior-lateral to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral superior medial protocerebrum and the ipsilateral crepine (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). There are approximately 9 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB2018 group, with its soma in the brain, anterior-lateral to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral superior medial protocerebrum and the ipsilateral crepine (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). There are approximately 7 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB2245 group, with its soma in the brain, anterior-lateral to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine and the ipsilateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 9 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB2293 group, with its soma in the brain, anterior-lateral to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine, the contralateral crepine, the ipsilateral lateral accessory lobe, the ipsilateral superior intermediate protocerebrum and the contralateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 7 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB2357 group, with its soma in the brain, anterior to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). There are approximately 10 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB2469 group, with its soma in the brain, anterior-lateral to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine, the ipsilateral superior medial protocerebrum and the ipsilateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 5 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB2776 group, with its soma in the brain, anterior to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine, the ipsilateral superior medial protocerebrum and the ipsilateral superior intermediate protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine, the contralateral superior intermediate protocerebrum, the ipsilateral superior intermediate protocerebrum, the contralateral crepine and the ipsilateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 4 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB2781 group, with its soma in the brain, anterior to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine, the ipsilateral superior intermediate protocerebrum and the ipsilateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 3 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB2784 group, with its soma in the brain, anterior-lateral to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine, the ipsilateral superior medial protocerebrum and the ipsilateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral lateral accessory lobe (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 5 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB2860 group, with its soma in the brain, anterior-lateral to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). There are approximately 3 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CB3077 group, with its soma in the brain, anterior to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the CRE056 group, with its soma in the brain, anterior to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral crepine and the ipsilateral superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). There are approximately 6 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Any neuron (FBbt:00005106) that develops from some neuroblast DALv2 (FBbt:00050136).
Ring neuron that develops from the DALv2 neuroblast during the larval stage (Lovick et al., 2017; Omoto et al., 2018; Bridi et al., 2019). Its small soma is located in a cluster just dorsolateral to the antennal lobe and ventrolateral to the lateral accessory lobe (LAL) (Hanesch et al., 1989). There are approximately 150 R-neurons per hemisphere, making them more abundant than the extrinsic ring neurons (Omoto et al., 2018). They have projections that extend dorsoposteriorly, branching off localized neurites with postsynaptic terminals into the bulb or, less frequently, the LAL (Young and Armstrong, 2010; Omoto et al., 2018). They enter the lateral ellipsoid fascicle, and via a circular process, terminate medially into the ellipsoid body (EB) (Omoto et al., 2018). In the EB, distal neurites of R-neurons either project centrifugally (inside-out) or centripetally (outside-in) (Omoto et al., 2018) and have presynaptic terminals there (Young and Armstrong, 2010). They are GABAergic (Bridi et al., 2019). All subtypes have functions in regulating sleep (Yan et al., 2023).
R-neuron that passes through the ellipsoid body canal, entering the neuropil from the posterior part of the canal and projecting outwards and slightly anteriorly (Omoto et al., 2018). Its terminals define the boundary between the inner and outer posterior layers of the ellipsoid body (Omoto et al., 2018). Unlike most other R-neurons, its dendritic branches are found on the lateral surface of the lateral accessory lobe, rather than the bulb (Omoto et al., 2018).
R-neuron that enters the ellipsoid body from the central canal, projects centrifugally, and has axon terminals throughout the outer central domain of the ellipsoid body (Hanesch et al., 1989; Young and Armstrong, 2010; Omoto et al., 2018). It does not arborize in a narrow region on the outermost periphery of this domain, which is where R4d terminals are found (Omoto et al., 2018). Proximal dendrites of R2 form club-shaped glomerular endings in the medial two-thirds of the superior bulb (Omoto et al., 2018).
R-neuron that has centrifugal projections into the ellipsoid body; there are several subclasses, but they all arborize more proximally than R2 and more anteriorly than R1 (Omoto et al., 2018).
Ring neuron R3 that enters the ellipsoid body centrifugally and arborizes in a region of the inner central domain surrounding the anterior domain (Omoto et al., 2018). Different subtypes have dendrites that target either a small region of the dorsal lateral accessory lobe, close to the anterior bulb, or a small region of the inferior bulb (Omoto et al., 2018; Okubo et al., 2020; Hulse et al., 2021).
Ring neuron R3 that projects along the lateral ellipsoid body fascicle toward the anterior ellipsoid body surface, turns posteriorly into the central canal, then spreads centrifugally throughout the inner central domain, partially overlapping with R3m and R3a (Omoto et al., 2018). Microglomerular dendritic endings of R3d fill the posterior region of the inferior bulb, and a few additional microglomeruli are observed in the dorso-medial part of the anterior region of the inferior bulb (Omoto et al., 2018).
Ring neuron R3 that enters the ellipsoid body centrifugally and arborizes in a region of the inner central domain complementary to, and partially overlapping with, R3d (Omoto et al., 2018). Its dendrites are relatively confined to the anterior part of the inferior bulb, but fibrous projections also extend to the lateral accessory lobe (Omoto et al., 2018). It is involved in regulating sleep depth (Yan et al., 2023).
Ring neuron R3 that has axonal projections predominantly restricted to, and densely filling, the ellipsoid body inner posterior domain, with some projections extending anteriorly and entering the inner central domain (Omoto et al., 2018). Dendritic branches form microglomerular shapes in the posterior part of the inferior bulb (Omoto et al., 2018). Its activity increases the amount of daytime sleep (Yan et al., 2023).
Ring neuron R3 that has axonal projections that enter the ellipsoid body centrifugally and arborize along the boundary between the inner central and inner posterior domains, reaching the inner part of the outer central domain (Omoto et al., 2018). Glomerular dendritic endings occupy a medial region within the superior bulb (Omoto et al., 2018).
R-neuron that arborizes only in the outer central domain of the ellipsoid body (Renn et al., 1999; Omoto et al., 2018). Arborizing branches enter the ellipsoid body from the periphery and extend inwards, centripetally (Hanesch et al., 1989; Omoto et al., 2018).
Ring neuron R4 whose arborization in the ellipsoid body is largely restricted to the outermost part of the ellipsoid body outer central domain (Renn et al., 1999; Omoto et al., 2018). It has glomerular dendrites restricted to the lateral part of the superior bulb (Omoto et al., 2018). In the ellipsoid body, it synapses to E-PG neurons, as well as forming inhibitory connections with other R4d neurons (Turner-Evans et al., 2020). It is GABAergic (Turner-Evans et al., 2020).
Ring neuron R4 whose arborization in the ellipsoid body fills most of the ellipsoid body outer central domain, except for the region occupied by R4d terminals (Renn et al., 1999; Omoto et al., 2018). It has dendrites in the anterior bulb (Omoto et al., 2018). It responds to temperature increases and mediates thermoresponsive behavior (Buhl et al., 2021). It activity decreases the amount of nighttime sleep (Yan et al., 2023).
R-neuron whose axons specifically target the small, anterior domain of the ellipsoid body, projecting short terminal branches centripetally (Omoto et al., 2017; Omoto et al., 2018). Dendritic terminals are confined to a small distinct ventromedial locus in the superior bulb (Omoto et al., 2018).
R-neuron whose distal neurites enter the ellipsoid body centripetally and form a sparse mesh along the posterior and postero-lateral boundary of the outer posterior domain, with short branches also extending anteriorly into this domain (Omoto et al., 2018). Proximal neurites have a unique projection pattern, first forming dense branches within the gall, and then continuing into the bulb, where they show a web-like innervation reaching throughout the anterior, inferior and superior bulb (Omoto et al., 2018). There are two of these cells per hemisphere (Omoto et al., 2018).
Immature secondary neuron that will become an adult ellipsoid body R1 neuron (Xie et al., 2017).
Immature secondary neuron that will become an adult ellipsoid body R2 neuron (Xie et al., 2017).
Immature secondary neuron that will become an adult ellipsoid body R3 neuron (Xie et al., 2017).
Immature secondary neuron that will become an adult ellipsoid body R4d neuron (Xie et al., 2017).
Immature secondary neuron that will become an adult ellipsoid body R4m neuron (Xie et al., 2017).
Immature secondary neuron of the larva that arises from neuroblast DALv2 and is a precursor to an adult ellipsoid body R-neuron (Lovick et al., 2017). It has filopodia in the bulb primordium and in the anterior ellipsoid body primordium (Lovick et al., 2017).
Larval neuron that has presynapses in the ipsilateral centroposterior medial compartment (posterior inferior protocerebrum) and postsynapses in the ipsilateral mushroom body lower vertical lobe (V1) (Saumweber et al., 2018). It is GABAergic (Eichler et al., 2017). It outputs onto FBN-20 (Eschbach et al., 2020). It develops from neuroblast DALv2 (Saumweber et al., 2018; Kandimalla et al., 2023) and becomes a LAL.s-NO2i.b (LNO1) neuron during metamorphosis (Truman et al., 2023).
Larval neuron that has presynapses in the ipsilateral centroposterior medial compartment (posterior inferior protocerebrum) and postsynapses in the ipsilateral mushroom body lower vertical lobe (V1) (Saumweber et al., 2018). It is GABAergic (Eichler et al., 2017). It develops from neuroblast DALv2 (Saumweber et al., 2018; Kandimalla et al., 2023) and becomes a LAL.s-NO2i.b (LNO1) neuron during metamorphosis (Truman et al., 2023).
Nodulus-innervating adult neuron that targets only ipsilateral brain regions and has its cell body ventral to the lateral accessory lobe (LAL) (Wolff and Rubin, 2018). It extends dorsally and has predominantly postsynaptic arbors throughout the LAL (Wolff and Rubin, 2018). It then projects medially to ipsilateral nodulus 2, where its presynaptic terminals densely innervate both compartments (Wolff and Rubin, 2018). Its lateral accessory lobe arbor may creep slightly into the crepine (Wolff and Rubin, 2018; Hulse et al., 2021). There are two of these cells per hemisphere and are they are part of the DALv2 primary lineage (Kandimalla et al., 2023), developing from the larval MBONs g1 and g2 (Truman et al., 2023).
Adult brain-intrinsic neuron of the SIP027 group, with its soma in the brain, anterior to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral superior intermediate protocerebrum, the ipsilateral superior medial protocerebrum and the ipsilateral crepine (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral superior medial protocerebrum, the ipsilateral superior intermediate protocerebrum, the contralateral superior medial protocerebrum and the contralateral superior intermediate protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 8 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
Adult brain-intrinsic neuron of the SIP028 group, with its soma in the brain, lateral to the gall (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the EBa1 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral superior medial protocerebrum, the ipsilateral crepine and the ipsilateral superior intermediate protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral superior medial protocerebrum, the contralateral superior medial protocerebrum and the ipsilateral crepine (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is gaba (Eckstein et al., 2024). There are approximately 5 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).