adult DL2 lineage clone [FBbt_00050084]
A clone of neurons in the adult brain, all of which develop from neuroblast CP3.
Tag: lineage_DL2_CP3
adult DL2 lineage neuron [FBbt_00050085]
Any neuron (FBbt:00005106) that is part of some adult (FBbt:00003004) and develops from some neuroblast CP3 (FBbt:00100610).
adult fruitless pIP-a (female) neuron [FBbt_00110479]
Adult female fruitless neuron that develops from neuroblast DL2 (CP3) (Ren et al., 2016) and has its cell body in the posterior inferior protocerebrum (Yu et al., 2010). In the brain, it has arbors in the lateral protocerebral complex (Yu et al., 2010). It descends to the ventral nerve cord, where it has presynaptic terminals in all three thoracic neuromeres (Cachero et al., 2010; Yu et al., 2010). There are approximately 3 of these cells per hemisphere (Ren et al., 2016).
adult fruitless pIP-a (male) neuron [FBbt_00110609]
Adult male fruitless neuron that develops from neuroblast DL2 (CP3) (Ren et al., 2016) and has its cell body in the posterior inferior protocerebrum (Yu et al., 2010). In the brain, it has arbors in the lateral protocerebral complex (Yu et al., 2010). It descends to the ventral nerve cord, where it has presynaptic terminals in all three thoracic neuromeres (Cachero et al., 2010; Yu et al., 2010). There are approximately 22 of these cells per hemisphere (Ren et al., 2016).
CP3 lineage neuron [FBbt_00100708]
Any neuron (FBbt:00005106) that develops from some neuroblast CP3 (FBbt:00100610).
DL2 secondary intermediate neural progenitor 1 [FBbt_00053317]
First intermediate neural progenitor to be born from neuroblast DL2 (CP3) during the post-embryonic stage (Wang et al., 2014). It produces a significantly smaller clone than first-born secondary INPs of other lineages (Wang et al., 2014).
fru-pIP-a [FBbt_00052705]
Adult fruitless neuron that develops from neuroblast DL2 (CP3) (Ren et al., 2016) and has its cell body in the posterior inferior protocerebrum (Yu et al., 2010). In the brain, it has arbors in the lateral protocerebral complex (Yu et al., 2010). It descends to the ventral nerve cord, where it has presynaptic terminals in all three thoracic neuromeres (Cachero et al., 2010; Yu et al., 2010). There are many more of these cells in males than females (Ren et al., 2016).
larval mushroom body dopaminergic neuron c1 [FBbt_00110342]
Larval dopaminergic neuron of the DL1 cluster that projects to both spurs and to the anterior parts of the pedunculi of the mushroom bodies (Selcho et al., 2009). In contrast to the other DL1 subtypes, the neurite which innervates the dorsomedial protocerebrum bifurcates laterally to the vertical lobe with an axon innervating this lobe. It has postsynapses in the anterior and posterior superior medial protocerebrum (dorsoanterior and dorsoposterior compartments). It receives input from FBNs, FFN-2, and FFN-15 (Eschbach et al., 2020). It develops from the CP3 (DL2) neuroblast and becomes a PPL101 (MB-MP1) neuron during metamorphosis (Saumweber et al., 2018; Truman et al., 2023).
larval mushroom body dopaminergic neuron d1 [FBbt_00110341]
Larval dopaminergic neuron of the DL1 cluster that projects to both lateral appendices of the mushroom bodies (Selcho et al., 2009). The primary neurite extends dorsally, and bifurcates in the lateral appendix and basomedial protocerebrum, while a secondary neurite emerges posterior to the vertical lobe and crosses the midline (Selcho et al., 2009). Postsynapses are found in the dorsoposterior compartment (posterior superior medial protocerebrum), basocentral compartment (lateral accessory lobe) and centroposterior medial compartment (posterior inferior protocerebrum). Presynapses are found in the mushroom body lateral appendix (Saumweber et al., 2018). It is activated downstream of class IV multidendritic neurons and basin neurons and it receives direct input from FBNs, FFNs, FB2Ns (Eschbach et al., 2020). It develops from the DL2 (CP3) neuroblast in the embryo and develops into a PPL103 (MB-MV1) cell during metamorphosis (Saumweber et al., 2018; Truman et al., 2023).
larval mushroom body dopaminergic neuron f1 [FBbt_00110339]
Larval dopaminergic neuron of the DL1 cluster that projects to the region beneath the dorsal tips (V2) of both vertical lobes (Selcho et al., 2009). It has postsynaptic sites in the anterior and posterior superior medial protocerebrum and the centroposterior lateral compartment (clamp) (Saumweber et al., 2018). It is activated downstream of mechanosensory chordotonal neurons and class IV multidendritic neurons and it receives direct input from FBNs, FFNs, FB2N-12 and FB2N-18 (Eschbach et al., 2020). It develops from the CP3 (DL2) neuroblast and develops into an adult PPL1 SMP neuron during metamorphosis (Saumweber et al., 2018; Truman et al., 2023).
larval mushroom body dopaminergic neuron g1 [FBbt_00110340]
Larval dopaminergic neuron of the DL1 cluster that mainly projects to the contralateral mushroom body, to the ventral region (V1) of the vertical lobe, posterior to the lateral appendix (Selcho et al., 2009). Ipsilateral arborizations are present in the dorsomedial and parts of the basomedial protocerebrum. It also innervates a small region of the protocerebrum basal to the mushroom body lobes in both hemispheres (Selcho et al., 2009). Its postsynaptic terminals are mainly found in the superior medial protocerebrum and crepine and its presynapses are mainly found in the lower vertical lobe (V1) of the mushroom body and in the centroanterior compartment (lateral accessory lobe) and centroposterior intermediate compartment (posterior inferior protocerebrum) (Saumweber et al., 2018). It is activated downstream of mechanosensory chordotonal neurons, class IV multidendritic neurons and basin neurons and it receives direct input from FAN-10, FAN-11 and FB2N-12 (Eschbach et al., 2020). It develops from the CP3 (DL2) neuroblast and develops into an adult PPL1 02 neuron during metamorphosis (Saumweber et al., 2018; Truman et al., 2023).
larval mushroom body input neuron c1 [FBbt_00047963]
Larval neuron with postsynaptic terminals in the anterior and posterior superior medial protocerebrum (dorsoanterior and dorsoposterior compartments) and presynaptic terminals in the mushroom body lower pedunculus (spur region) (Saumweber et al., 2018). It develops from the CP3 (DL2) neuroblast late in embryogenesis and becomes a PPL101 (MB-MP1) neuron during metamorphosis (Saumweber et al., 2018; Truman et al., 2023).
larval mushroom body input neuron e2 [FBbt_00110338]
Larval dopaminergic neuron of the DL1 cluster that projects to the dorsal tips (V3 segment) of both vertical lobes of the mushroom body (Selcho et al., 2009). It has postsynaptic sites in the anterior and posterior superior medial protocerebrum (Saumweber et al., 2018). It receives input from FBNs, FFNs, FB2N-12 and FB2N-19 (Eschbach et al., 2020). It develops from the CP3 (DL2) neuroblast (Saumweber et al., 2018; Truman et al., 2023).
larval mushroom body octopaminergic/tyraminergic neuron e1 [FBbt_00047973]
Larval neuron with its soma posterior to the vertical lobe, presynapses in the dorsal tip (V3 segment) of the ipsilateral vertical lobe of the mushroom body and postsynaptic sites in the anterior and posterior superior medial protocerebrum (Saumweber et al., 2018). This neuron is tyraminergic (Eichler et al., 2017). It receives input from FBNs, FB2Ns and FFNs (Eschbach et al., 2020). It develops from the CP3 (DL2) neuroblast and develops into an adult PPL1 SMP-gamma neuron during metamorphosis (Saumweber et al., 2018; Truman et al., 2023).
larval mushroom body output neuron a1 [FBbt_00047965]
Larval odd neuron with its soma just posterior to the mushroom body (Mohamed et al., 2023). It receives input in the ipsilateral calyx, predominantly from Kenyon cells (Saumweber et al., 2018; Mohamed et al., 2023), and has presynaptic terminals in the regions surrounding the ipsilateral and contralateral medial lobes (Mohamed et al., 2023). It is synapsed to MBIN-e1 and FAN-8 (Eschbach et al., 2020). It is involved in odor-based learning (Mohamed et al., 2023) and its activity inhibits turning behavior (Eschbach et al., 2021). It develops from neuroblast CP3 (DL2) and becomes adult MBON29 during metamorphosis (Saumweber et al., 2018; Truman et al., 2023).
larval mushroom body output neuron a2 [FBbt_00047966]
Larval odd neuron with its soma just posterior to the mushroom body (Mohamed et al., 2023). It receives input in the ipsilateral calyx, predominantly from Kenyon cells (Saumweber et al., 2018; Mohamed et al., 2023), and has presynaptic terminals in the regions surrounding the ipsilateral and contralateral medial lobes (Mohamed et al., 2023). It is involved in odor-based learning (Mohamed et al., 2023) and its activity promotes turning behavior (Eschbach et al., 2021). It develops from neuroblast CP3 (DL2) and becomes adult MBON22 during metamorphosis (Saumweber et al., 2018; Truman et al., 2023).
larval mushroom body output neuron b3 [FBbt_00047962]
Larval neuron that has postsynaptic terminals in the intermediate region of the mushroom body pedunculus and presynaptic terminals in the centroposterior lateral and intermediate compartments (clamp) and the centroposterior medial compartment (posterior inferior protocerebrum) (Saumweber et al., 2018). It is synapsed to MBIN-e1 (Eschbach et al., 2020). It develops from neuroblast CP3 (DL2) (Saumweber et al., 2018; Truman et al., 2023).
larval mushroom body output neuron e1 [FBbt_00047972]
Larval neuron that has presynapses in the dorsoposterior compartment (posterior superior medial protocerebrum) and dorsoanterior compartment (anterior superior medial protocerebrum) and postsynapses in the mushroom body vertical lobe tip region (V3) (Saumweber et al., 2018). It is cholinergic (Eichler et al., 2017). It outputs onto FBN-4, FBN-10, FBN-12, FBN-13, FBN-17, FAN-4, FAN-7 and FAN-11 (Eschbach et al., 2020). Its activity inhibits turning behavior (Eschbach et al., 2021). It develops from the CP3 (DL2) neuroblast (Saumweber et al., 2018; Truman et al., 2023).
LHPV5a1 [FBbt_00049407]
Adult lateral horn output neuron of the PV5a1 group that fasciculates with the PV5 primary neurite tract (Frechter et al., 2019; Dolan et al., 2019) There are approximately 7-11 of these neurons per hemisphere and they are cholinergic (Dolan et al., 2019; Bates et al., 2020; Schlegel et al., 2021). They are secondary neurons that are part of the CP3 (DL2) dorsal hemilineage (Bates et al., 2020; Schlegel et al., 2021).
LHPV5a2 [FBbt_00049408]
Adult lateral horn output neuron of the PV5a2 group that fasciculates with the PV5 primary neurite tract (Frechter et al., 2019). There are four of these cells per hemisphere and they are secondary neurons that are part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). They are cholinergic (Schlegel et al., 2021).
LHPV5a3 [FBbt_00049409]
Adult lateral horn output neuron of the PV5a3 group that fasciculates with the PV5 primary neurite tract (Frechter et al., 2019; Dolan et al., 2019). These cells are secondary neurons that are part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). There are approximately 4-5 of these neurons per hemisphere and they are cholinergic (Dolan et al., 2019; Schlegel et al., 2021).
LHPV5a4 [FBbt_00051512]
Adult lateral horn output neuron of the PV5a4 group that fasciculates with the PV5 primary neurite tract and is part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). There are two of these cells per hemisphere and they are cholinergic (Schlegel et al., 2021).
LHPV5a5 [FBbt_00049695]
Adult lateral horn output neuron of the PV5a5 group that fasciculates with the PV5 primary neurite tract (Bates et al., 2020). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Bates et al., 2020). There are two of these cells per hemisphere and they are cholinergic (Bates et al., 2020; Schlegel et al., 2021).
LHPV5b1 [FBbt_00049410]
Adult lateral horn output neuron of the PV5b1 group that fasciculates with the PV5 primary neurite tract (Frechter et al., 2019; Dolan et al., 2019). It belongs to the DL2 (CP3) dorsal hemilineage (Schlegel et al., 2021). There are approximately seven of these neurons per hemisphere and they are cholinergic (Dolan et al., 2019; Schlegel et al., 2021).
LHPV5b2 [FBbt_00049411]
Adult lateral horn output neuron of the PV5b2 group that fasciculates with the PV5 primary neurite tract (Frechter et al., 2019; Dolan et al., 2019). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). There are approximately 5-7 of these neurons per hemisphere and they are cholinergic (Dolan et al., 2019; Schlegel et al., 2021).
LHPV5b3 [FBbt_00049412]
Adult lateral horn output neuron of the PV5b3 group that fasciculates with the PV5 primary neurite tract (Frechter et al., 2019; Dolan et al., 2019). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). There are 4-5 of these neurons per hemisphere and they are cholinergic (Dolan et al., 2019; Schlegel et al., 2021).
LHPV5b4 [FBbt_00051513]
Adult lateral horn output neuron of the PV5b4 group that fasciculates with the PV5 primary neurite tract (Schlegel et al., 2021). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). There are approximately three of these neurons per hemisphere and they are cholinergic (Schlegel et al., 2021).
LHPV5b5 [FBbt_00051514]
Adult lateral horn output neuron of the PV5b5 group that fasciculates with the PV5 primary neurite tract (Schlegel et al., 2021). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). There are approximately 1-2 of these neurons per hemisphere and they are cholinergic (Schlegel et al., 2021).
LHPV5b6 [FBbt_00051515]
Adult lateral horn output neuron of the PV5b6 group that fasciculates with the PV5 primary neurite tract (Schlegel et al., 2021). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). There are approximately 4-5 of these neurons per hemisphere and they are cholinergic (Schlegel et al., 2021).
LHPV5c3 [FBbt_00049415]
Adult lateral horn output neuron of the PV5c3 group that fasciculates with the PV5 primary neurite tract (Frechter et al., 2019). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). There are 1-3 of these cells per hemisphere and they are cholinergic (Bates et al., 2020; Schlegel et al., 2021).
LHPV5d1 [FBbt_00049416]
Adult lateral horn output neuron of the PV5d1 group that fasciculates with the PV5 primary neurite tract (Frechter et al., 2019). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Bates et al., 2020). There are approximately six of these cells per hemisphere and they are cholinergic (Bates et al., 2020; Schlegel et al., 2021).
LHPV5d2 [FBbt_00051517]
Adult lateral horn output neuron of the PV5d2 group that fasciculates with the PV5 primary neurite tract (Schlegel et al., 2021). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). There is one of these cells per hemisphere and it is cholinergic (Schlegel et al., 2021).
LHPV5d3 [FBbt_00049696]
Adult lateral horn output neuron of the PV5d3 group that fasciculates with the PV5 primary neurite tract (Bates et al., 2020). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Bates et al., 2020). There is one of these cells per hemisphere and it is cholinergic (Bates et al., 2020; Schlegel et al., 2021).
LHPV5f1 [FBbt_00051520]
Adult lateral horn output neuron of the PV5f1 group that fasciculates with the PV5 primary neurite tract (Schlegel et al., 2021). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Schlegel et al., 2021). There is one of these neurons per hemisphere and it is cholinergic (Schlegel et al., 2021).
LHPV5g1 [FBbt_00049417]
Adult lateral horn output neuron of the PV5g1 group that fasciculates with the PV5 primary neurite tract (Dolan et al., 2019). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Bates et al., 2020). It is cholinergic (Dolan et al., 2019; Bates et al., 2020).
LHPV5g2 [FBbt_00049418]
Adult lateral horn output neuron of the PV5g2 group that fasciculates with the PV5 primary neurite tract (Dolan et al., 2019). It is a secondary neuron that is part of the CP3 (DL2) dorsal hemilineage (Bates et al., 2020). There are four of these cells per hemisphere and they are cholinergic (Dolan et al., 2019; Bates et al., 2020; Schlegel et al., 2021).
MBON22 [FBbt_00100240]
A neuron whose cell body is located on the posteriorlateral protocerebrum, ventrolateral to the calyx of the adult brain. The cell body fiber projects to and arborizes with the pedunculus where it bifurcates, with one branch turning posteriorly to extensively arborize in the calyx with a few fibers extending into the lateral horn. The other branch projects anteriorly through the pedunculus, turns medially and runs below the medial lobe. The fiber then turns dorsally and bifurcates, forming terminals in the crepine in both hemispheres. There is one of these cells per hemisphere (Aso et al., 2014; Li et al., 2020). It is involved in retrieval of reward and punishment memory (Ichinose et al., 2021). It develops from the larval MBON-a2 (Truman et al., 2023).
MBON29 [FBbt_00049849]
Atypical mushroom body output neuron whose dendrites arborize in the gamma lobe slices 4 and 5, similar to MBON21 (Li et al., 2020). It also has dendritic arborization outside of the mushroom body, predominantly in the crepine (in both hemispheres) and the superior medial protocerebrum, with some postsynaptic sites in the contralateral gamma lobe (Li et al., 2020). Its presynaptic terminals are mainly found contralaterally, in the crepine and superior medial protocerebrum (Li et al., 2020). There is 1 neuron of this type in each hemisphere (Li et al., 2020). It develops from the larval MBON-a1 (Truman et al., 2023).
PPL101 [FBbt_00100243]
A neuron whose cell body is located on the inferior neuropils, lateral to the mushroom body calyx (Tanaka et al., 2008), in the dopaminergic PPL1 cluster (Aso et al., 2014). It develops from a larval mushroom body input neuron of the CP3 (DL2) lineage (Truman et al., 2023). The cell body fiber runs anteriormedially and diverges above the ellipsoid body (Tanaka et al., 2008). Its dendrite forms four main arbors, in the superior intermediate protocerebrum, superior medial protocerebrum, dorsal crepine and ventral crepine (Otto et al., 2020). Another fiber turns ventromedially and projects to the opposite hemisphere (Tanaka et al., 2008; Li et al., 2020). A third fiber (axonal) turns ventrolaterally, runs in front of the anterior surface of the gamma lobe and then below the gamma lobe, and arborizes in the spur of the gamma lobe (slice 1) and inner core of the pedunculus (Tanaka et al., 2008; Li et al., 2020; Otto et al., 2020). The contralateral fiber innervates the same mushroom body regions (Li et al., 2020). There are 1-2 neurons of this type per hemisphere (Aso et al., 2014; Li et al., 2020; Otto et al., 2020; Truman et al., 2023). It is involved in food odor attraction (Sayin et al., 2019).
PPL102 [FBbt_00111025]
A dopaminergic neuron of the PPL1 cluster that has sparse terminals in the gamma lobe slice 1 (Aso et al., 2014; Li et al., 2020). It crosses the midline and has a broader arborization in the contralateral hemisphere (Truman et al., 2023). There is one neuron of this type in each hemisphere (Aso et al., 2014; Li et al., 2020). It develops from a larval DAN-g1 neuron (Truman et al., 2023).
PPL103 [FBbt_00100241]
A neuron whose cell body is located in the inferior neuropils, lateral to the mushroom body calyx (Tanaka et al., 2008), in the dopaminergic PPL1 cluster (Aso et al., 2014). The cell body fiber projects towards the anterior of the inferior neuropils and on the way there it bifurcates with one branch turning ventrally and terminating in the ventral complex (Tanaka et al., 2008). The second branch further branches in the crepine close to the beta lobe (Tanaka et al., 2008), with dendritic arborization (Aso et al., 2020). One fiber runs medially to the opposite hemisphere (Tanaka et al., 2008). Another turns ventrolaterally and arborizes in the basal segments of the gamma lobe (slice 2) and alpha’ lobe (slice 1) (Tanaka et al., 2008; Li et al., 2020). The contralateral fiber innervates the same mushroom body regions (Li et al., 2020). The final branch arborizes in the superior medial protocerebrum (Tanaka et al., 2008), with dendritic arborization (Aso et al., 2014). There is one neuron of this type in each hemisphere (Aso et al., 2014; Li et al., 2020) and it develops from the larval DAN-d1 (Truman et al., 2023). It is involved in aversive learning and forgetting (Berry et al., 2018).
PPL104 [FBbt_00110321]
PPL1 neuron whose main axon innervates the tip of the mushroom body alpha’ lobe (segment 3) (Mao and Davis, 2009; Aso et al., 2014; Li et al., 2020). A fiber also crosses the midline to innervate the contralateral alpha’ lobe tip (Mao and Davis, 2009; Li et al., 2020). Most of its dendritic arborizations are found in the superior intermediate and lateral protocerebrum, with a smaller amount in the superior medial protocerebrum and lateral horn (Aso et al., 2014). There is one neuron of this type in each hemisphere (Aso et al., 2014; Li et al., 2020) and it develops from the CP3 (DL2) neuroblast during larval development (Ren et al., 2016).
PPL105 [FBbt_00100236]
A dopaminergic neuron of the PPL1 cluster that has its cell body in the superior neuropils lateral to the calyx (Tanaka et al., 2008; Aso et al., 2014). The cell body fiber projects anterior-medially and forms dendritic branches in the superior neuropils posterior to the vertical lobes (Tanaka et al., 2008; Aso et al., 2014). One of these branches projects to the opposite hemisphere and others project to the vertical lobe and form extensive arborizations in the middle segment of both the alpha and alpha’ lobes (slice 2) (Tanaka et al., 2008; Aso et al., 2014). The contralateral branch innervates the same mushroom body regions (Li et al., 2020), There is one neuron of this type in each hemisphere (Aso et al., 2014; Li et al., 2020) and it develops from the CP3 (DL2) neuroblast during larval development (Ren et al., 2016). It plays an important role in retrieval of alcohol-associated memory (Scaplen et al., 2020).
PPL106 [FBbt_00110320]
PPL1 cluster dopaminergic neuron with axonal projections to the tip of the mushroom body alpha lobe (segment 3) (Mao and Davis, 2009; Aso et al., 2014) in both hemispheres (Li et al., 2020). Most of its dendritic arborizations are found in the superior medial and lateral protocerebrum, with a smaller amount in the superior intermediate protocerebrum and lateral horn (Aso et al., 2014). There is one neuron of this type in each hemisphere (Aso et al., 2014; Li et al., 2020) and it develops from the first intermediate neuronal progenitor the CP3 (DL2) neuroblast to be born during larval development (Wang et al., 2014; Ren et al., 2016).
SMP neuron of the dopaminergic PPL1 cluster [FBbt_00048269]
Bilateral MB-SV neuron that has terminals in the superior medial protocerebrum, in addition to the area surrounding the vertical lobe (Xie et al., 2018). It develops from a larval DAN-f1 neuron (Truman et al., 2023).
SMP-gamma neuron of the dopaminergic PPL1 cluster [FBbt_00048251]
Unilateral MB-SV neuron that has terminals in the mushroom body gamma lobe and the superior medial protocerebrum, in addition to the area surrounding the vertical lobe (Xie et al., 2018). It develops from the larval OAN-e1 cell (Truman et al., 2023).