Malpighian tubule Type I cell [FBbt_00005796]
Morphologically distinct cell type found throughout the Malpighian tubules. It is a large epithelial cell joined by septate junctions to other Type I cells, with apical microvilli and infolding of the basal membrane. There are small differences between Type I cells in different tubule segments: in the initial segment, the cells have few microvilli and are relatively narrow compared with the larger, flatter cells of the main segment. Type I cells originate from division of the ectodermal Malpighian tubules primordial cells that are found in the junction between the hindgut and midgut. Type I cell proliferation is complete by late stage 13 of embryogenesis. In the mature tubules there are on average 484 Type I cells. These cells are involved in primary urine production via the secretion of K+ into the lumen by a vacuolar-type H+ ATPase transporter and K+/H+ exchanger (Davies et al., 1996; Linton and O’Donnell, 1999).
Note
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VFB Term Json
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"label": "Malpighian tubule Type I cell"
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"description": [
"Morphologically distinct cell type found throughout the Malpighian tubules. It is a large epithelial cell joined by septate junctions to other Type I cells, with apical microvilli and infolding of the basal membrane. There are small differences between Type I cells in different tubule segments: in the initial segment, the cells have few microvilli and are relatively narrow compared with the larger, flatter cells of the main segment. Type I cells originate from division of the ectodermal Malpighian tubules primordial cells that are found in the junction between the hindgut and midgut. Type I cell proliferation is complete by late stage 13 of embryogenesis. In the mature tubules there are on average 484 Type I cells."
],
"comment": [
"These cells are involved in primary urine production via the secretion of K+ into the lumen by a vacuolar-type H+ ATPase transporter and K+/H+ exchanger (Davies et al., 1996; Linton and O'Donnell, 1999)."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
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