neuroblast NB5-4 [FBbt_00001416]

Neuroblast NB5-4 most frequently delaminates at S4 in an intermediate column. In the third instar larva, the lineage originated by this neuroblast is located at the ventro-lateral region of the neuromere. Using DiI with antibody labelling, Schmidt et al., (1997) propose NB5-4 produces 5-9 thoracic neurons or 3-4 abdominal motorneurons with ipsilateral targets. Schmid et al., (1999), also use DiI with en-GFP, but find 2-3 large cells that match descriptions of CCAP/CAP+ neurosecretory cells, along with abdomen-specific interneurons. Also, Schmid et al., (1999) state that NB5-4 delaminates during S5, whilst Schmidt et al., (1997) find that delamination occurs over the period of S3/4 to S5, most frequently at S4, and as such we have chosen to define NB5-4 as a stage 4 neuroblast. According to Lacin and Truman (2016), this neuroblast resumes proliferation in the larva and generates postembryonic lineage 22. However, according to Birkholz et al. (2015) it generates lineage 20 or 22.
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Open neuroblast NB5-4 in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/FBbt_00001416",
            "symbol": "",
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            "short_form": "FBbt_00001416",
            "label": "neuroblast NB5-4"
        },
        "description": [
            "Neuroblast NB5-4 most frequently delaminates at S4 in an intermediate column. In the third instar larva, the lineage originated by this neuroblast is located at the ventro-lateral region of the neuromere."
        ],
        "comment": [
            "Using DiI with antibody labelling, Schmidt et al., (1997) propose NB5-4 produces 5-9 thoracic neurons or 3-4 abdominal motorneurons with ipsilateral targets. Schmid et al., (1999), also use DiI with en-GFP, but find 2-3 large cells that match descriptions of CCAP/CAP+ neurosecretory cells, along with abdomen-specific interneurons. Also, Schmid et al., (1999) state that NB5-4 delaminates during S5, whilst Schmidt et al., (1997) find that delamination occurs over the period of S3/4 to S5, most frequently at S4, and as such we have chosen to define NB5-4 as a stage 4 neuroblast. According to Lacin and Truman (2016), this neuroblast resumes proliferation in the larva and generates postembryonic lineage 22. However, according to Birkholz et al. (2015) it generates lineage 20 or 22."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
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            "short_form": "FBbt_00005147",
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            "short_form": "FBbt_00001409",
            "label": "stage 4 neuroblast"
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