lamina intrinsic neuron [FBbt_00003746]

Intrinsic neuron of the lamina with arborizations spanning the proximal and distal lamina, whose cell body lies proximal to the lamina (Fischbach and Dittrich, 1989; Meinertzhagen and Sorra, 2001). It has extensive arborizations and forms a substantial number of presynaptic terminals with columnar neuron T1 and epithelial glia (Rivera-Alba et al., 2011). It receives strong input from each of photoreceptors R1-R6, and from lamina wide-field cells (Rivera-Alba et al., 2011). It is a glutamatergic neuron (Davis et al., 2020). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for Lai (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (-/36), R2 (1/39), R3 (-/39), R4 (2/37), R5 (2/35), R6 (-/40), L1 (1/-), L2 (1/-), L3 (10/-), L4 (4/2), L5 (4/-), Lai (1), T1 (54/1), C2 (1/5), C3 (1/9), Lawf (-/24) and epithelial glia (87/-) (Rivera-Alba et al., 2011).

Open lamina intrinsic neuron in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00003746",
            "symbol": "Lai",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Glutamatergic",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00003746",
            "label": "lamina intrinsic neuron"
        },
        "description": [
            "Intrinsic neuron of the lamina with arborizations spanning the proximal and distal lamina, whose cell body lies proximal to the lamina (Fischbach and Dittrich, 1989; Meinertzhagen and Sorra, 2001). It has extensive arborizations and forms a substantial number of presynaptic terminals with columnar neuron T1 and epithelial glia (Rivera-Alba et al., 2011). It receives strong input from each of photoreceptors R1-R6, and from lamina wide-field cells (Rivera-Alba et al., 2011). It is a glutamatergic neuron (Davis et al., 2020)."
        ],
        "comment": [
            "Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. The number of synaptic connections for Lai (presynaptic/postsynaptic) in a single lamina cartridge with each cell type was the following: R1 (-/36), R2 (1/39), R3 (-/39), R4 (2/37), R5 (2/35), R6 (-/40), L1 (1/-), L2 (1/-), L3 (10/-), L4 (4/2), L5 (4/-), Lai (1), T1 (54/1), C2 (1/5), C3 (1/9), Lawf (-/24) and epithelial glia (87/-) (Rivera-Alba et al., 2011)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00058208",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Glutamatergic",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00058208",
            "label": "adult glutamatergic neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00003702",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00003702",
            "label": "adult optic lobe neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00003745",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00003745",
            "label": "lamina tangential neuron"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003708",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_domain"
                ],
                "short_form": "FBbt_00003708",
                "label": "lamina"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013009",
                "label": "sends_synaptic_output_to_cell",
                "type": "sends_synaptic_output_to_cell"
            },
            "object": {
                "symbol": "T1",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003727",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00003727",
                "label": "columnar neuron T1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013009",
                "label": "sends_synaptic_output_to_cell",
                "type": "sends_synaptic_output_to_cell"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00100513",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Glial_cell",
                    "Nervous_system"
                ],
                "short_form": "FBbt_00100513",
                "label": "adult lamina epithelial glial cell"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003708",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_domain"
                ],
                "short_form": "FBbt_00003708",
                "label": "lamina"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "R4",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00004219",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Nervous_system",
                    "Neuron",
                    "Sensory_neuron"
                ],
                "short_form": "FBbt_00004219",
                "label": "photoreceptor cell R4"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "R2",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00004215",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Nervous_system",
                    "Neuron",
                    "Sensory_neuron"
                ],
                "short_form": "FBbt_00004215",
                "label": "photoreceptor cell R2"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "R6",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00004223",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Nervous_system",
                    "Neuron",
                    "Sensory_neuron"
                ],
                "short_form": "FBbt_00004223",
                "label": "photoreceptor cell R6"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "R5",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00004221",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Nervous_system",
                    "Neuron",
                    "Sensory_neuron"
                ],
                "short_form": "FBbt_00004221",
                "label": "photoreceptor cell R5"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "R1",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00004213",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Nervous_system",
                    "Neuron",
                    "Sensory_neuron"
                ],
                "short_form": "FBbt_00004213",
                "label": "photoreceptor cell R1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "Lawf1",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003741",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Class",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00003741",
                "label": "lamina wide-field 1 neuron"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "R3",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00004217",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Nervous_system",
                    "Neuron",
                    "Sensory_neuron"
                ],
                "short_form": "FBbt_00004217",
                "label": "photoreceptor cell R3"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002100",
                "label": "has soma location",
                "type": "has_soma_location"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00100206",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system"
                ],
                "short_form": "FBbt_00100206",
                "label": "cell body rind of adult lamina"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "amacrine cell",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0049410",
                    "types": [
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                    ],
                    "short_form": "FBrf0049410",
                    "label": "Fischbach and Dittrich, 1989, Cell Tissue Res. 258(3): 441--475"
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "Am",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0159582",
                    "types": [
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                    ],
                    "short_form": "FBrf0159582",
                    "label": "Meinertzhagen and Sorra, 2001, Prog. Brain Res. 131: 53--69"
                },
                "FlyBase": "",
                "PubMed": "11420968",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "Lai",
                "type": ""
            },
            "pub": {
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    ],
    "def_pubs": [
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                "types": [
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                ],
                "short_form": "FBrf0216925",
                "label": "Rivera-Alba et al., 2011, Curr. Biol. 21(23): 2000--2005"
            },
            "FlyBase": "",
            "PubMed": "22119527",
            "DOI": "10.1016/j.cub.2011.10.022"
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                ],
                "short_form": "FBrf0244935",
                "label": "Davis et al., 2020, eLife 9: e50901"
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            "FlyBase": "FBrf0244935",
            "PubMed": "31939737",
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}