SMP454 [FBbt_20003316]

Adult descending neuron of the SMP454 group, with its soma in the brain, dorsal to the superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral superior medial protocerebrum, the ipsilateral inferior clamp, the contralateral superior medial protocerebrum, the ipsilateral superior posterior slope, the ipsilateral superior clamp, the ipsilateral inferior bridge, the ipsilateral flange and the ipsilateral gorget (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the contralateral superior medial protocerebrum, the ipsilateral superior medial protocerebrum, the contralateral flange, the gnathal ganglia, the prow, the saddle, the contralateral superior clamp, the contralateral superior lateral protocerebrum, the contralateral posterior lateral protocerebrum and the ipsilateral flange (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
SMP454 SMP454 SMP454 SMP454

SMP454

ID: FBbt_20003316

Adult Cholinergic Nervous system primary neuron

Adult descending neuron of the SMP454 group, with its soma in the brain, dorsal to the superior medial protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral superior medial protocerebrum, the ipsilateral inferior clamp, the contralateral superior medial protocerebrum, the ipsilateral superior posterior slope, the ipsilateral superior clamp, the ipsilateral inferior bridge, the ipsilateral flange and the ipsilateral gorget (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the contralateral superior medial protocerebrum, the ipsilateral superior medial protocerebrum, the contralateral flange, the gnathal ganglia, the prow, the saddle, the contralateral superior clamp, the contralateral superior lateral protocerebrum, the contralateral posterior lateral protocerebrum and the ipsilateral flange (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).

Uncharacterized putative cell type based on Hemibrain data (Scheffer et al., 2020) and updated using FlyWire (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024). Soma locations are based on the closest annotated neuropil region. Pre- or post-synapse locations are the fewest regions that collectively contain at least 80 percent of all pre- or post-synapses of these neurons in FlyWire. Neurotransmitter predictions are from Eckstein et al. (2024). Other annotations are based on annotations in FlyWire and are available in the supplemental material of Schlegel et al. (2024).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
DNpe053 related synonym doi_10_1038_s41586-025-08746-0
DNpe053 exact synonym Bates et al., 2025
DNpe053 exact synonym Berg et al., 2025
SMP454 exact synonym Scheffer et al., 2020
DNpe053 exact synonym Schlegel et al., 2024
DNpe053 exact synonym Nern et al., 2025
DNpe053 related synonym

List all available images of SMP454 (12 total)

Thumbnail Name Tags
DNpe053(SMP454)_L (MaleCNS:10286) Nervous_system, primary_neuron, Adult, Cholinergic
DNpe053(SMP454)_L (MaleCNS:10286) Nervous_system, primary_neuron, Adult, Cholinergic
DNpe053(SMP454)_R (MaleCNS:20418) Nervous_system, primary_neuron, Adult, Cholinergic
DNpe053(SMP454)_R (MaleCNS:20418) Nervous_system, primary_neuron, Adult, Cholinergic
SMP454_R Nervous_system, primary_neuron, Adult, Cholinergic

View all 12 results in VFB →

Downstream connectivity classes for SMP454 (637 total)

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Upstream connectivity classes for SMP454 (490 total)

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