PLP221 [FBbt_20001721]

Adult brain-intrinsic neuron of the PLP221 group, with its soma in the brain, posterior to the inferior posterior slope (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral posterior lateral protocerebrum and the ipsilateral wedge (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the contralateral lateral accessory lobe, the contralateral crepine and the ipsilateral posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
PLP221 PLP221 PLP221 PLP221

PLP221

ID: FBbt_20001721

Adult Cholinergic Nervous system primary neuron

Adult brain-intrinsic neuron of the PLP221 group, with its soma in the brain, posterior to the inferior posterior slope (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral posterior lateral protocerebrum and the ipsilateral wedge (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the contralateral lateral accessory lobe, the contralateral crepine and the ipsilateral posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).

Uncharacterized putative cell type based on Hemibrain data (Scheffer et al., 2020) and updated using FlyWire (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024). Soma locations are based on the closest annotated neuropil region. Pre- or post-synapse locations are the fewest regions that collectively contain at least 80 percent of all pre- or post-synapses of these neurons in FlyWire. Neurotransmitter predictions are from Eckstein et al. (2024). Other annotations are based on annotations in FlyWire and are available in the supplemental material of Schlegel et al. (2024).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
PLP221 exact synonym Bates et al., 2025
PLP221 exact synonym Scheffer et al., 2020
PLP221 exact synonym Schlegel et al., 2024
PLP221 exact synonym Berg et al., 2025
PLP221 exact synonym

List all available images of PLP221 (7 total)

Thumbnail Name Tags
PLP221_L (MaleCNS:79269) Nervous_system, primary_neuron, Adult, Cholinergic
PLP221_R (MaleCNS:19717) Nervous_system, primary_neuron, Adult, Cholinergic
PLP221_R Nervous_system, primary_neuron, Adult, Cholinergic
PLP221_R Nervous_system, primary_neuron, Adult, Cholinergic
PLP221_R Nervous_system, primary_neuron, Adult, Cholinergic

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Downstream connectivity classes for PLP221 (128 total)

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Upstream connectivity classes for PLP221 (82 total)

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