MeVPOL1 [FBbt_20004334]

Adult interneuron with its soma ventral to the lateral horn (Schlegel et al., 2024; Dorkenwald et al., 2024). In the ipsilateral optic lobe, it receives input mainly in layers M4 and M8, from around 300 columns each (Nern et al., 2025). In the contralateral optic lobe, it projects to the vicinity of the inner optic chiasm, then innervates medulla layers M8 and M10, lobula layers 2-3 and lobula plate layer 1, where it is mainly presynaptic in around 50 columns of each (Nern et al., 2025). It does not have substantial synapsing outside of the optic lobes (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024; Nern et al., 2025). There is one of these cells per hemisphere (Nern et al., 2025).
MeVPOL1 MeVPOL1 MeVPOL1 MeVPOL1

MeVPOL1

ID: FBbt_20004334

Adult Cholinergic Nervous system Visual system

Adult interneuron with its soma ventral to the lateral horn (Schlegel et al., 2024; Dorkenwald et al., 2024). In the ipsilateral optic lobe, it receives input mainly in layers M4 and M8, from around 300 columns each (Nern et al., 2025). In the contralateral optic lobe, it projects to the vicinity of the inner optic chiasm, then innervates medulla layers M8 and M10, lobula layers 2-3 and lobula plate layer 1, where it is mainly presynaptic in around 50 columns of each (Nern et al., 2025). It does not have substantial synapsing outside of the optic lobes (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024; Nern et al., 2025). There is one of these cells per hemisphere (Nern et al., 2025).

Cell type from Schlegel et al. (2024), based on FlyWire v783 (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024), identified at light level by Nern et al. (2025). Soma location is based on the closest annotated neuropil region in FlyWire.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
MeMe_e13 exact synonym Schlegel et al., 2024
MeVPOL1 exact synonym Berg et al., 2025
MeVPOL1 exact synonym Nern et al., 2025
adult MeMe_e13 neuron exact synonym
MeMe_e13 exact synonym Bates et al., 2025
CB0592 exact synonym

List all available images of MeVPOL1 (7 total)

Thumbnail Name Tags
ME.LO.1 Nervous_system, Visual_system, Adult, Cholinergic
ME.LO.1 Nervous_system, Visual_system, Adult, Cholinergic
MeVPOL1_L (MaleCNS:10060) Nervous_system, Adult, Visual_system, Cholinergic
MeVPOL1_R (MaleCNS:10330) Nervous_system, Adult, Visual_system, Cholinergic
MeVPOL1_R (MaleCNS:10330) Nervous_system, Adult, Visual_system, Cholinergic

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Downstream connectivity classes for MeVPOL1 (267 total)

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Upstream connectivity classes for MeVPOL1 (169 total)

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