MeVPMe12 [FBbt_20004523]

Adult interneuron with its soma ventral to the protocerebral bridge (Schlegel et al., 2024; Dorkenwald et al., 2024). In the ipsilateral optic lobe, its main arborization domain is the layer M3-M4 border, where it has postsynapses and a smaller number of presynapses, spanning around 150 columns (Nern et al., 2025). It has additional presynapses in layers M1 and M6-M7 in around 30 columns each (Nern et al., 2025). In the contralateral optic lobe, it is mainly presynaptic in around 100 columns of medulla layer M1 (Nern et al., 2025). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024; Nern et al., 2025). There are approximately two of these cells per hemisphere (Nern et al., 2025).
MeVPMe12 MeVPMe12 MeVPMe12 MeVPMe12

MeVPMe12

ID: FBbt_20004523

Adult Cholinergic Nervous system Visual system

Adult interneuron with its soma ventral to the protocerebral bridge (Schlegel et al., 2024; Dorkenwald et al., 2024). In the ipsilateral optic lobe, its main arborization domain is the layer M3-M4 border, where it has postsynapses and a smaller number of presynapses, spanning around 150 columns (Nern et al., 2025). It has additional presynapses in layers M1 and M6-M7 in around 30 columns each (Nern et al., 2025). In the contralateral optic lobe, it is mainly presynaptic in around 100 columns of medulla layer M1 (Nern et al., 2025). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024; Nern et al., 2025). There are approximately two of these cells per hemisphere (Nern et al., 2025).

Cell type from Schlegel et al. (2024), based on FlyWire v783 (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024), identified at light level by Nern et al. (2025). Soma location is based on the closest annotated neuropil region in FlyWire. All FlyWire cells have some synapses in the PVLP, so this does not seem to be an intrinsic neuron.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
MeVPMe12 exact synonym Berg et al., 2025
MeMe_e11 exact synonym Bates et al., 2025
adult MeMe_e11 neuron exact synonym
MeMe_e11 exact synonym Schlegel et al., 2024
MeVPMe12 exact synonym Nern et al., 2025
CB0816 exact synonym

List all available images of MeVPMe12 (17 total)

Thumbnail Name Tags
MeVPMe12_L (MaleCNS:10443) Nervous_system, Visual_system, Adult, Cholinergic
MeVPMe12_L (MaleCNS:10451) Nervous_system, Visual_system, Adult, Cholinergic
MeVPMe12_R (MaleCNS:10358) Nervous_system, Adult, Visual_system, Cholinergic
MeVPMe12_R (MaleCNS:10358) Nervous_system, Adult, Visual_system, Cholinergic
MeVPMe12_R (MaleCNS:515278) Nervous_system, Visual_system, Adult, Cholinergic

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Downstream connectivity classes for MeVPMe12 (163 total)

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Upstream connectivity classes for MeVPMe12 (157 total)

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