MeLo2 [FBbt_20007251]

Adult unilateral optic-lobe-intrinsic neuron with its soma lateral to the accessory medulla (Schlegel et al., 2024; Dorkenwald et al., 2024). It bifurcates near the soma, sending one branch to the medulla and one to the lobula, without passing through the optic chiasm (Nern et al., 2025). It receives input in medulla layers M1-4 in around 10-20 columns and has mixed terminals in a few columns of lobula layers 4 and 5A (Nern et al., 2025). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024; Nern et al., 2025). There are approximately 60 of these cells per hemisphere (Nern et al., 2025).
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MeLo2

ID: FBbt_20007251

Adult Cholinergic Nervous system Visual system

Adult unilateral optic-lobe-intrinsic neuron with its soma lateral to the accessory medulla (Schlegel et al., 2024; Dorkenwald et al., 2024). It bifurcates near the soma, sending one branch to the medulla and one to the lobula, without passing through the optic chiasm (Nern et al., 2025). It receives input in medulla layers M1-4 in around 10-20 columns and has mixed terminals in a few columns of lobula layers 4 and 5A (Nern et al., 2025). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024; Nern et al., 2025). There are approximately 60 of these cells per hemisphere (Nern et al., 2025).

Cell type from Schlegel et al. (2024), based on FlyWire v783 (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024), identified at light level by Nern et al. (2025). Soma location is based on the closest annotated neuropil region in FlyWire.

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
MLt3 exact synonym Schlegel et al., 2024
CB3836 exact synonym Schlegel et al., 2024
MLt3 exact synonym Nern et al., 2025
MLt3 exact synonym Bates et al., 2025
MeLo2 exact synonym Nern et al., 2025
MeLo2 exact synonym Berg et al., 2025
adult CB3836 neuron exact synonym

List all available images of MeLo2 (347 total)

Thumbnail Name Tags
MeLo2_L (MaleCNS:26745) Nervous_system, Adult, Visual_system, Cholinergic
MeLo2_L (MaleCNS:533059) Nervous_system, Visual_system, Adult, Cholinergic
MeLo2_L (MaleCNS:575913) Nervous_system, Visual_system, Adult, Cholinergic
MeLo2_R (MaleCNS:28921) Nervous_system, Visual_system, Adult, Cholinergic
MeLo2_R (MaleCNS:35134) Nervous_system, Visual_system, Adult, Cholinergic

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Downstream connectivity classes for MeLo2 (262 total)

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Upstream connectivity classes for MeLo2 (219 total)

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