LPLC2 [FBbt_00111763]

LPLC2

ID: FBbt_00111763

Lobula plate-lobula columnar neuron whose cell body lies in the dorsal area of the lateral cell body rind (Wu et al., 2016). It has a distinct dendritic arbor in each lobula plate layer, extending outwards from the main fiber in the direction of motion detection for the layer (Klapoetke et al., 2017). This arrangement allows it to detect looming (expansion) stimuli (Klapoetke et al., 2017). In the lobula, it has its main dendritic arbors in layers 4 and 5B, with minor processes in layer 5A, and presynaptic sites in layer 4 (Wu et al., 2016; Tanaka and Clark, 2022). Its arbors span approximately 25 lobula optic columns, overlapping with other LPLC2 cells (Wu et al., 2016). It projects to an optic glomerulus of the PVLP, anterior to LPLC1 and dorsal to LC4 (Wu et al., 2016). Its activity elicits a jump escape response (Wu et al., 2016; Klapoetke et al., 2017). There are approximately 80 of these cells per optic lobe (Wu et al., 2016) and they are cholinergic (Davis et al., 2020).

Pre- versus postsynaptic innervation assessed with a presynaptic marker (synaptotagmin-HA driver) (Wu et al., 2016).