LoVC1 [FBbt_20001289]

LoVC1

ID: FBbt_20001289

Adult glutamatergic visual centrifugal neuron with its soma in the brain, ventral-lateral to the anterior optic tubercle (Dorkenwald et al., 2024; Schlegel et al., 2024; Schretter et al., 2025). It extends to the contralateral hemisphere then bifurcates, with a branch looping round ventrally back to the ipsilateral hemisphere and producing roughly symmetrical arbors in the central brain (Schretter et al., 2025). The other branch innervates the contralateral anterior optic tubercle and lobula, where it has most of its presynapses (Schretter et al., 2025). It extends multiple branches into the proximal lobula, where it innervates more than 50 columns of layers 5 and 6 (Nern et al., 2025). Its inputs are mainly in the central brain, including the superior medial and intermediate protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It is predicted to be a primary neuron (Dorkenwald et al., 2024; Schlegel et al., 2024). There is one of these cells per hemisphere (Dorkenwald et al., 2024; Schlegel et al., 2024; Schretter et al., 2025).

Cell type based on Hemibrain data (Scheffer et al., 2020), updated using FlyWire (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024) and identified at light level by Schretter et al. (2025). Soma location is based on the closest annotated neuropil region and pre- or post-synapse locations are the fewest regions that collectively contain at least 80 percent of all pre- or post-synapses of these neurons in FlyWire.