transcription preinitiation complex assembly [GO_0070897]

The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC). The PIC engages the RNA polymerase on its DNA template strand and sparks polymerization of the first few RNA nucleotides.

Tags:

Class
GO

transcription preinitiation complex assembly

ID: GO_0070897

Class

The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC). The PIC engages the RNA polymerase on its DNA template strand and sparks polymerization of the first few RNA nucleotides.

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Classification

protein-DNA complex assembly

Relationships

is part of: DNA-templated transcription initiation

Alternative Names

Synonym	Scope	Reference
bacterial-type RNA polymerase transcriptional preinitiation complex formation	narrow synonym
bacterial-type RNA polymerase transcription PIC formation	narrow synonym
bacterial-type RNA polymerase preinitiation complex assembly	narrow synonym
transcription PIC formation	broad synonym	mah
transcription PIC biosynthesis	broad synonym	mah
transcriptional preinitiation complex formation	broad synonym	mah
DNA-templated transcriptional preinitiation complex assembly	exact synonym
DNA-dependent transcriptional preinitiation complex assembly	exact synonym	txnOH

References

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