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Gene Ontology (GO)

The Gene Ontology (GO) provides a framework and set of concepts for describing the functions of gene products from all organisms.

Open in the Ontology Lookup Service (OLS)

1 - ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose [GO_0004135]

Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.

Open ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004135",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004135",
            "label": "((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose"
        },
        "description": [
            "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0090599",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0090599",
            "label": "alpha-glucosidase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "amylo-1,6-glucosidase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "dextrin-1,6-glucosidase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

2 - (1->3)-beta-D-glucan binding [GO_0001872]

Binding to a (1->3)-beta-D-glucan.

Open (1->3)-beta-D-glucan binding in VFB

Term Information

  • ID: GO_0001872
  • Name: (1->3)-beta-D-glucan binding
  • Definition: Binding to a (1->3)-beta-D-glucan.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0001872",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0001872",
            "unique_facets": [
                "Class"
            ],
            "label": "(1->3)-beta-D-glucan binding"
        },
        "description": [
            "Binding to a (1->3)-beta-D-glucan."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0030247",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0030247",
            "unique_facets": [
                "Class"
            ],
            "label": "polysaccharide binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1,3-beta-D-glucan binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "callose binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "zymosan binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

3 - (1->3)-beta-D-glucan immune receptor activity [GO_0001874]

Combining with (1->3)-beta-D-glucans to initiate an innate immune response.

Open (1->3)-beta-D-glucan immune receptor activity in VFB

Term Information

  • ID: GO_0001874
  • Name: (1->3)-beta-D-glucan immune receptor activity
  • Definition: Combining with (1->3)-beta-D-glucans to initiate an innate immune response.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0001874",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0001874",
            "unique_facets": [
                "Class"
            ],
            "label": "(1->3)-beta-D-glucan immune receptor activity"
        },
        "description": [
            "Combining with (1->3)-beta-D-glucans to initiate an innate immune response."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "08f7a30",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0001873",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0001873",
            "unique_facets": [
                "Class"
            ],
            "label": "polysaccharide immune receptor activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000051",
                "label": "has part",
                "type": "has_part"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0001872",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0001872",
                "unique_facets": [
                    "Class"
                ],
                "label": "(1->3)-beta-D-glucan binding"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "(1->3)-beta-D-glucan receptor activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1,3-beta-D-glucan receptor activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "beta-1,3-D-glucan receptor activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "(1,3)-beta-D-glucan receptor activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "zymosan receptor activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

4 - (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) [GO_0004001]

Catalysis of the reaction: ATP + adenosine = ADP + AMP.

Open (2’-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004001",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004001",
            "label": "(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK)"
        },
        "description": [
            "Catalysis of the reaction: ATP + adenosine = ADP + AMP."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019206",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0019206",
            "label": "nucleoside kinase activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016773",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016773",
            "label": "phosphotransferase activity, alcohol group as acceptor"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0006167",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0006167",
                "label": "AMP biosynthetic process"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adenosine 5-phosphotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ATP:adenosine 5'-phosphotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

5 - (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity [GO_0019171]

Catalysis of the reaction: a (3R)-hydroxyacyl-[acyl-carrier-protein] = a (2E)-enoyl-[acyl-carrier-protein] + H2O.

Open **(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity** in VFB

Term Information

  • ID: GO_0019171
  • Name: (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
  • Definition: Catalysis of the reaction: a (3R)-hydroxyacyl-[acyl-carrier-protein] = a (2E)-enoyl-[acyl-carrier-protein] + H2O.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0019171",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0019171",
            "unique_facets": [
                "Class"
            ],
            "label": "(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"
        },
        "description": [
            "Catalysis of the reaction: a (3R)-hydroxyacyl-[acyl-carrier-protein] = a (2E)-enoyl-[acyl-carrier-protein] + H2O."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016836",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016836",
            "unique_facets": [
                "Class"
            ],
            "label": "hydro-lyase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-hydroxyacyl-ACP dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-hydroxyacyl-[acyl-carrier protein] dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "(3R)-3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

6 - (d)ADP + ADP <=> (d)AMP + ATP (AK1) [GO_0004017]

Catalysis of the reaction: ATP + AMP = 2 ADP.

Open (d)ADP + ADP <=> (d)AMP + ATP (AK1) in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004017",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004017",
            "label": "(d)ADP + ADP <=> (d)AMP + ATP (AK1)"
        },
        "description": [
            "Catalysis of the reaction: ATP + AMP = 2 ADP."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0050145",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0050145",
            "label": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "myokinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

7 - (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) [GO_0050145]

Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate.

Open (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0050145",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0050145",
            "label": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)"
        },
        "description": [
            "Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016776",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016776",
            "label": "phosphotransferase activity, phosphate group as acceptor"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019205",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0019205",
            "label": "nucleobase-containing compound kinase activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0046940",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0046940",
                "label": "nucleoside monophosphate phosphorylation"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "nucleotide kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "nucleoside-phosphate kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "NMP-kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

8 - (d)GMP + ATP <=> (d)GDP + ADP (GUK1) [GO_0004385]

Catalysis of the reaction: ATP + GMP = ADP + GDP.

Open (d)GMP + ATP <=> (d)GDP + ADP (GUK1) in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004385",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004385",
            "label": "(d)GMP + ATP <=> (d)GDP + ADP (GUK1)"
        },
        "description": [
            "Catalysis of the reaction: ATP + GMP = ADP + GDP."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0050145",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0050145",
            "label": "(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1)"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0046037",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0046037",
                "label": "GMP metabolic process"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0046710",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0046710",
                "label": "GDP metabolic process"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "membrane-associated guanylate kinase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

9 - (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) [GO_0004550]

Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.

Open (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004550",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004550",
            "label": "(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3)"
        },
        "description": [
            "Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016776",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016776",
            "label": "phosphotransferase activity, phosphate group as acceptor"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019205",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0019205",
            "label": "nucleobase-containing compound kinase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "nucleoside-diphosphate kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "nucleotide phosphate kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

10 - (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity [GO_0070626]

Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.

Open (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity in VFB

Term Information

  • ID: GO_0070626
  • Name: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity
  • Definition: Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0070626",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0070626",
            "unique_facets": [
                "Class"
            ],
            "label": "(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"
        },
        "description": [
            "Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016842",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016842",
            "unique_facets": [
                "Class"
            ],
            "label": "amidine-lyase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "SAICAR-lyase (fumarate forming) activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

11 - (S)-2-hydroxy-acid oxidase activity [GO_0003973]

Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.

Open (S)-2-hydroxy-acid oxidase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003973",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003973",
            "label": "(S)-2-hydroxy-acid oxidase activity"
        },
        "description": [
            "Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016899",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016899",
            "label": "oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "glycolate oxidase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "medium-chain-(S)-2-hydroxy-acid oxidase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "L-2-hydroxy acid oxidase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "L-alpha-hydroxy acid oxidase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "hydroxyacid oxidase A",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "very-long-chain-(S)-2-hydroxy-acid oxidase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "hydroxy-acid oxidase B activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

12 - [acyl-carrier-protein] S-malonyltransferase activity [GO_0004314]

Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein].

Open **[acyl-carrier-protein] S-malonyltransferase activity** in VFB

Term Information

  • ID: GO_0004314
  • Name: [acyl-carrier-protein] S-malonyltransferase activity
  • Definition: Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein].
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004314",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004314",
            "unique_facets": [
                "Class"
            ],
            "label": "[acyl-carrier-protein] S-malonyltransferase activity"
        },
        "description": [
            "Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein]."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016419",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016419",
            "unique_facets": [
                "Class"
            ],
            "label": "S-malonyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "[acyl-carrier protein] S-malonyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ACP S-malonyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "malonyl-CoA:AcpM transacylase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

13 - [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [GO_0008467]

Catalysis of the reaction: 3’-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3’,5’-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.

Open [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008467",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008467",
            "label": "[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity"
        },
        "description": [
            "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0034483",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0034483",
            "label": "heparan sulfate sulfotransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "heparin-glucosamine 3-O-sulphotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "heparin-glucosamine 3-O-sulfotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

14 - [heparan sulfate]-glucosamine N-sulfotransferase activity [GO_0015016]

Catalysis of the reaction: 3’-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3’,5’-bisphosphate + [heparan sulfate]-N-sulfoglucosamine. Note that this activity includes EC:2.8.2.12 (deleted from EC).

Open [heparan sulfate]-glucosamine N-sulfotransferase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0015016",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015016",
            "label": "[heparan sulfate]-glucosamine N-sulfotransferase activity"
        },
        "description": [
            "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine."
        ],
        "comment": [
            "Note that this activity includes EC:2.8.2.12 (deleted from EC)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0034483",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0034483",
            "label": "heparan sulfate sulfotransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "heparin N-deacetylase/N-sulfotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "heparitin N-sulfotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "desulfoheparin sulfotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "heparin N-deacetylase/N-sulphotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "heparitin N-sulphotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "[heparan sulphate]-glucosamine N-sulphotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "heparitin sulfotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "heparin-glucosamine N-sulfotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "N-desulfoheparin sulfotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

15 - [pyruvate dehydrogenase (lipoamide)] phosphatase activity [GO_0004741]

Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate.

Open **[pyruvate dehydrogenase (lipoamide)] phosphatase activity** in VFB

Term Information

  • ID: GO_0004741
  • Name: [pyruvate dehydrogenase (lipoamide)] phosphatase activity
  • Definition: Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004741",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004741",
            "unique_facets": [
                "Class"
            ],
            "label": "[pyruvate dehydrogenase (lipoamide)] phosphatase activity"
        },
        "description": [
            "Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004721",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004721",
            "unique_facets": [
                "Class"
            ],
            "label": "Dephosphorylation of phospho-Cdh1"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "pyruvate dehydrogenase (lipoamide) phosphatase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic catalyst activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "unique_facets": [
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "pyruvate dehydrogenase phosphatase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

16 - 1-acyl LPE is acylated to PE by LPEAT [GO_0003841]

Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.

Open 1-acyl LPE is acylated to PE by LPEAT in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003841",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003841",
            "label": "1-acyl LPE is acylated to PE by LPEAT"
        },
        "description": [
            "Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0042171",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0042171",
            "label": "lysophosphatidic acid acyltransferase activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016411",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016411",
            "label": "2-MAG and DAG are transacylated to TAG by PNPLA2/3"
        }
    ],
    "relationships": [],
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    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1-acyl-sn-glycerol-3-phosphate acyltransferase activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "lysophosphatidate acyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

17 - 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C [GO_0004622]

Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

Open 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C in VFB

VFB Term Json

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    "term": {
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            "iri": "http://purl.obolibrary.org/obo/GO_0004622",
            "symbol": "",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0004622",
            "label": "1-acyl LPE is hydrolyzed to GPETA by PLA2G4C"
        },
        "description": [
            "Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0052689",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0052689",
            "label": "CES1trimer hydrolyses ACEI pro-drugs to ACEIs"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004620",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004620",
            "label": "DDHD1,2 hydrolyse PA"
        }
    ],
    "relationships": [],
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    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "lecitholipase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

18 - 1-acylglycerophosphocholine O-acyltransferase activity [GO_0047184]

Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.

Open 1-acylglycerophosphocholine O-acyltransferase activity in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0047184",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0047184",
            "label": "1-acylglycerophosphocholine O-acyltransferase activity"
        },
        "description": [
            "Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008374",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008374",
            "label": "HHAT palmitoylates Hh N-terminal fragment"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acyl coenzyme A-monoacylphosphatidylcholine acyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

19 - 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate [GO_0008609]

Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.

Open 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate in VFB

Term Information

  • ID: GO_0008609
  • Name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate
  • Definition: Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008609",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008609",
            "unique_facets": [
                "Class"
            ],
            "label": "1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate"
        },
        "description": [
            "Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016765",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016765",
            "unique_facets": [
                "Class"
            ],
            "label": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "alkyldihydroxyacetone phosphate synthetase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

20 - 1-phosphatidylinositol 4-kinase activator activity [GO_0098744]

Binds to and increases the activity of 1-phosphatidylinositol 4-kinase.

Open 1-phosphatidylinositol 4-kinase activator activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0098744",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0098744",
            "label": "1-phosphatidylinositol 4-kinase activator activity"
        },
        "description": [
            "Binds to and increases the activity of 1-phosphatidylinositol 4-kinase."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140677",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140677",
            "label": "molecular function activator activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019207",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0019207",
            "label": "kinase regulator activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002211",
                "label": "regulates",
                "type": "regulates"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0004430",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0004430",
                "label": "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane"
            }
        }
    ],
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    "def_pubs": [
        {
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

21 - 1-phosphatidylinositol binding [GO_0005545]

Binding to a phosphatidylinositol, a glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.

Open 1-phosphatidylinositol binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0005545",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005545",
            "label": "1-phosphatidylinositol binding"
        },
        "description": [
            "Binding to a phosphatidylinositol, a glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0035091",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0035091",
            "label": "phosphatidylinositol binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
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    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

22 - 1-phosphatidylinositol-3-kinase regulator activity [GO_0046935]

Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity. See also the molecular function term ‘1-phosphatidylinositol-3-kinase activity ; GO:0016303’.

Open 1-phosphatidylinositol-3-kinase regulator activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0046935",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0046935",
            "label": "1-phosphatidylinositol-3-kinase regulator activity"
        },
        "description": [
            "Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity."
        ],
        "comment": [
            "See also the molecular function term '1-phosphatidylinositol-3-kinase activity ; GO:0016303'."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0035014",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0035014",
            "label": "phosphatidylinositol 3-kinase regulator activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002211",
                "label": "regulates",
                "type": "regulates"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0016303",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0016303",
                "label": "PI3K-containing complexes phosphorylate PIP2 to PIP3"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1-phosphatidylinositol 3-kinase regulator activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "phosphatidylinositol 3-kinase, class I, regulator activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

23 - 1-phosphatidylinositol-5-kinase activity [GO_0052810]

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H+.

Open 1-phosphatidylinositol-5-kinase activity in VFB

Term Information

  • ID: GO_0052810
  • Name: 1-phosphatidylinositol-5-kinase activity
  • Definition: Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H+.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0052810",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0052810",
            "unique_facets": [
                "Class"
            ],
            "label": "1-phosphatidylinositol-5-kinase activity"
        },
        "description": [
            "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0052742",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0052742",
            "unique_facets": [
                "Class"
            ],
            "label": "phosphatidylinositol kinase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1-phosphatidylinositol 5-kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
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                    "unique_facets": [
                        "pub"
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                    "label": ""
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                "PubMed": "",
                "DOI": ""
            }
        }
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            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

24 - 1-phosphatidylinositol-5-phosphate 4-kinase activity [GO_0016309]

Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

Open 1-phosphatidylinositol-5-phosphate 4-kinase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016309",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016309",
            "label": "1-phosphatidylinositol-5-phosphate 4-kinase activity"
        },
        "description": [
            "Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016307",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016307",
            "label": "phosphatidylinositol phosphate kinase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "1-phosphatidylinositol-5-phosphate kinase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "PIP4K",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "type II PIP kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

25 - 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol [GO_0000829]

Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.

Open 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0000829",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0000829",
            "label": "1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol"
        },
        "description": [
            "Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016776",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016776",
            "label": "phosphotransferase activity, phosphate group as acceptor"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016301",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016301",
            "label": "FN3KRP phosphorylates PsiAm, RibAm"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

26 - 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] [GO_0004144]

Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.

Open 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004144",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004144",
            "label": "1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]"
        },
        "description": [
            "Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016411",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016411",
            "label": "2-MAG and DAG are transacylated to TAG by PNPLA2/3"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "diacylglycerol acyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

27 - 1,4-alpha-glucan branching enzyme activity [GO_0003844]

Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.

Open 1,4-alpha-glucan branching enzyme activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003844",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003844",
            "label": "1,4-alpha-glucan branching enzyme activity"
        },
        "description": [
            "Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016758",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016758",
            "label": "hexosyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1,4-glucan-6-(1,4-glucano)-transferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "amylo-(1,4 to 1,6)transglucosidase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

28 - 1,4-alpha-oligoglucan phosphorylase activity [GO_0004645]

Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.

Open 1,4-alpha-oligoglucan phosphorylase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004645",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004645",
            "label": "1,4-alpha-oligoglucan phosphorylase activity"
        },
        "description": [
            "Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016758",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016758",
            "label": "hexosyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "muscle phosphorylase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

29 - 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol [GO_0052842]

Catalysis of the reaction: inositol diphosphate pentakisphosphate + H2O = inositol hexakisphosphate + phosphate.

Open 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0052842",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0052842",
            "label": "1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol"
        },
        "description": [
            "Catalysis of the reaction: inositol diphosphate pentakisphosphate + H2O = inositol hexakisphosphate + phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016462",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016462",
            "label": "pyrophosphatase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

30 - 14-3-3 protein binding [GO_0071889]

Binding to a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.

Open 14-3-3 protein binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0071889",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0071889",
            "label": "14-3-3 protein binding"
        },
        "description": [
            "Binding to a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0005515",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005515",
            "label": "protein binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

31 - 17-beta-hydroxysteroid dehydrogenase (NAD+) activity [GO_0044594]

Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+.

Open 17-beta-hydroxysteroid dehydrogenase (NAD+) activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0044594",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0044594",
            "label": "17-beta-hydroxysteroid dehydrogenase (NAD+) activity"
        },
        "description": [
            "Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004303",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004303",
            "label": "HSD17B2 oxidises estradiol (E2) to estrone (E1)"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

32 - 17-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO_0072582]

Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+.

Open 17-beta-hydroxysteroid dehydrogenase (NADP+) activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0072582",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0072582",
            "label": "17-beta-hydroxysteroid dehydrogenase (NADP+) activity"
        },
        "description": [
            "Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004303",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004303",
            "label": "HSD17B2 oxidises estradiol (E2) to estrone (E1)"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

33 - 17-beta-ketosteroid reductase activity [GO_0072555]

Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+.

Open 17-beta-ketosteroid reductase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0072555",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0072555",
            "label": "17-beta-ketosteroid reductase activity"
        },
        "description": [
            "Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0033764",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0033764",
            "label": "steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

34 - 2 H2O2 => O2 + 2 H2O [GO_0004096]

Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.

Open 2 H2O2 => O2 + 2 H2O in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004096",
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            "types": [
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                "Class"
            ],
            "short_form": "GO_0004096",
            "label": "2 H2O2 => O2 + 2 H2O"
        },
        "description": [
            "Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004601",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004601",
            "label": "peroxidase activity"
        }
    ],
    "relationships": [],
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    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "bacterial catalase-peroxidase activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
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                "DOI": ""
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        },
        {
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                "label": "catalase reaction",
                "type": ""
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "haem catalase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "heme catalase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "manganese catalase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

35 - 2 iron, 2 sulfur cluster binding [GO_0051537]

Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.

Open 2 iron, 2 sulfur cluster binding in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0051537",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0051537",
            "label": "2 iron, 2 sulfur cluster binding"
        },
        "description": [
            "Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0051536",
            "types": [
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                "Class"
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            "short_form": "GO_0051536",
            "label": "iron-sulfur cluster binding"
        }
    ],
    "relationships": [],
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        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2 Fe 2 S cluster binding",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
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                "scope": "has_exact_synonym",
                "label": "2 iron, 2 sulphur cluster binding",
                "type": ""
            },
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "iron-sulfur cluster 2Fe-2S binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "iron-sulphur cluster 2Fe-2S binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "diiron disulfide cluster binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
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                "PubMed": "",
                "DOI": ""
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        },
        {
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                "scope": "has_exact_synonym",
                "label": "2Fe-2S cluster binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "diiron disulphide cluster binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
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                    "pub"
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

36 - 2-(3-amino-3-carboxypropyl)histidine synthase activity [GO_0090560]

Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2].

Open 2-(3-amino-3-carboxypropyl)histidine synthase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0090560",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0090560",
            "label": "2-(3-amino-3-carboxypropyl)histidine synthase activity"
        },
        "description": [
            "Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2]."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016765",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016765",
            "label": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

37 - 2-hydroxy-3-methylhexadecanoyl-CoA lyase activity [GO_0106360]

Catalysis of the reaction: 2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.

Open 2-hydroxy-3-methylhexadecanoyl-CoA lyase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0106360",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0106360",
            "label": "2-hydroxy-3-methylhexadecanoyl-CoA lyase activity"
        },
        "description": [
            "Catalysis of the reaction: 2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0106359",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0106359",
            "label": "2-hydroxyacyl-CoA lyase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

38 - 2-hydroxyacyl-CoA lyase activity [GO_0106359]

Catalysis of the reaction: A 2-hydroxyacyl-CoA = formyl-CoA + a propanol.

Open 2-hydroxyacyl-CoA lyase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0106359",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0106359",
            "label": "2-hydroxyacyl-CoA lyase activity"
        },
        "description": [
            "Catalysis of the reaction: A 2-hydroxyacyl-CoA = formyl-CoA + a propanol."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016832",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016832",
            "label": "aldehyde-lyase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

39 - 2-hydroxyglutarate dehydrogenase activity [GO_0047545]

Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.

Open 2-hydroxyglutarate dehydrogenase activity in VFB

Term Information

  • ID: GO_0047545
  • Name: 2-hydroxyglutarate dehydrogenase activity
  • Definition: Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0047545",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0047545",
            "unique_facets": [
                "Class"
            ],
            "label": "2-hydroxyglutarate dehydrogenase activity"
        },
        "description": [
            "Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016614",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016614",
            "unique_facets": [
                "Class"
            ],
            "label": "Fgd1 reactivates F420"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "alpha-hydroxyglutarate dehydrogenase (NAD+ specific)",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

40 - 2-hydroxyglutarate dehydrogenase activity, forward reaction [GO_0061758]

Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor.

Open 2-hydroxyglutarate dehydrogenase activity, forward reaction in VFB

Term Information

  • ID: GO_0061758
  • Name: 2-hydroxyglutarate dehydrogenase activity, forward reaction
  • Definition: Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0061758",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0061758",
            "unique_facets": [
                "Class"
            ],
            "label": "2-hydroxyglutarate dehydrogenase activity, forward reaction"
        },
        "description": [
            "Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "08f7a30",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0047545",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0047545",
            "unique_facets": [
                "Class"
            ],
            "label": "2-hydroxyglutarate dehydrogenase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
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    "def_pubs": [
        {
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                "symbol": "",
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                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

41 - 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA [GO_0016830]

Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.

Open 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016830",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016830",
            "label": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA"
        },
        "description": [
            "Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016829",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016829",
            "label": "TYW1:FMN:4Fe-4S  transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe)"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "other carbon-carbon lyase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

42 - 2-iminobutanoate deaminase activity [GO_0120242]

Catalysis of the reaction: 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+).

Open 2-iminobutanoate deaminase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0120242",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0120242",
            "label": "2-iminobutanoate deaminase activity"
        },
        "description": [
            "Catalysis of the reaction: 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0120241",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0120241",
            "label": "2-iminobutanoate/2-iminopropanoate deaminase"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

43 - 2-iminobutanoate/2-iminopropanoate deaminase [GO_0120241]

Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5’-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5’-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates (from EC:3.5.99.10).

Open 2-iminobutanoate/2-iminopropanoate deaminase in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0120241",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0120241",
            "label": "2-iminobutanoate/2-iminopropanoate deaminase"
        },
        "description": [
            "Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17."
        ],
        "comment": [
            "This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates (from EC:3.5.99.10)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019239",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0019239",
            "label": "HRSP12 deaminates 2AA to 2OBUTA"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016810",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016810",
            "label": "NAAA hydrolyses NAEs to FAs and ethanolamine"
        }
    ],
    "relationships": [],
    "xrefs": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "imine intermediate deaminase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "2-iminobutanoate deaminase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
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                "DOI": ""
            }
        }
    ],
    "def_pubs": []
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44 - 2-LTR formation due to circularization of viral DNA [GO_0003909]

Catalysis of the formation of a phosphodiester bond between the 3’-hydroxyl group at the end of one DNA chain and the 5’-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.

Open 2-LTR formation due to circularization of viral DNA in VFB

Term Information

  • ID: GO_0003909
  • Name: 2-LTR formation due to circularization of viral DNA
  • Definition: Catalysis of the formation of a phosphodiester bond between the 3’-hydroxyl group at the end of one DNA chain and the 5’-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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        "core": {
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            "symbol": "",
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                "has_subClass"
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            "short_form": "GO_0003909",
            "unique_facets": [
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            ],
            "label": "2-LTR formation due to circularization of viral DNA"
        },
        "description": [
            "Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+."
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        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140097",
            "types": [
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                "Class",
                "has_subClass"
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            "short_form": "GO_0140097",
            "unique_facets": [
                "Class"
            ],
            "label": "catalytic activity, acting on DNA"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016886",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016886",
            "unique_facets": [
                "Class"
            ],
            "label": "ligase activity, forming phosphoric ester bonds"
        }
    ],
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                    "pub"
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                "label": ""
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            "FlyBase": "",
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            "DOI": ""
        }
    ]
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45 - 2-MAG and DAG are transacylated to TAG by PNPLA2/3 [GO_0016411]

Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule.

Open 2-MAG and DAG are transacylated to TAG by PNPLA2/3 in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016411",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016411",
            "label": "2-MAG and DAG are transacylated to TAG by PNPLA2/3"
        },
        "description": [
            "Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008374",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008374",
            "label": "HHAT palmitoylates Hh N-terminal fragment"
        }
    ],
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                "symbol": "",
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
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46 - 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] [GO_0051990]

Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.

Open 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0051990",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0051990",
            "label": "2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1]"
        },
        "description": [
            "Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016614",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016614",
            "label": "Fgd1 reactivates F420"
        }
    ],
    "relationships": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "D-2-hydroxyglutarate dehydrogenase activity",
                "type": ""
            },
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
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        }
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
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            "DOI": ""
        }
    ]
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47 - 2-oxoglutarate-dependent dioxygenase activity [GO_0016706]

Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.

Open 2-oxoglutarate-dependent dioxygenase activity in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016706",
            "symbol": "",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0016706",
            "label": "2-oxoglutarate-dependent dioxygenase activity"
        },
        "description": [
            "Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016705",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016705",
            "label": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0051213",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0051213",
            "label": "dioxygenase activity"
        }
    ],
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        {
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                "scope": "has_exact_synonym",
                "label": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",
                "type": ""
            },
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                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2-oxoglutarate dioxygenase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
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        }
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
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            "DOI": ""
        }
    ]
}

48 - 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate [GO_0004619]

Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate.

Open 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004619",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004619",
            "label": "2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate"
        },
        "description": [
            "Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016868",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016868",
            "label": "intramolecular transferase activity, phosphotransferases"
        }
    ],
    "relationships": [],
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        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "PGM",
                "type": ""
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "GriP mutase",
                "type": ""
            },
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                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

49 - 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O [GO_0004634]

Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.

Open 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004634",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004634",
            "label": "2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O"
        },
        "description": [
            "Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016836",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016836",
            "label": "hydro-lyase activity"
        }
    ],
    "relationships": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2-phospho-D-glycerate-hydrolase activity",
                "type": ""
            },
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                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "nervous-system specific enolase",
                "type": ""
            },
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
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                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

50 - 2'-deoxyribonucleotide biosynthetic process [GO_0009265]

The chemical reactions and pathways resulting in the formation of a 2’-deoxyribonucleotide, a compound consisting of 2’-deoxyribonucleoside (a base linked to a 2’-deoxyribose sugar) esterified with a phosphate group at either the 3’ or 5’-hydroxyl group of the sugar.

Open 2’-deoxyribonucleotide biosynthetic process in VFB

Term Information

  • ID: GO_0009265
  • Name: 2’-deoxyribonucleotide biosynthetic process
  • Definition: The chemical reactions and pathways resulting in the formation of a 2’-deoxyribonucleotide, a compound consisting of 2’-deoxyribonucleoside (a base linked to a 2’-deoxyribose sugar) esterified with a phosphate group at either the 3’ or 5’-hydroxyl group of the sugar.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0009265",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0009265",
            "unique_facets": [
                "Class"
            ],
            "label": "2'-deoxyribonucleotide biosynthetic process"
        },
        "description": [
            "The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0046385",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0046385",
            "unique_facets": [
                "Class"
            ],
            "label": "deoxyribose phosphate biosynthetic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009394",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0009394",
            "unique_facets": [
                "Class"
            ],
            "label": "2'-deoxyribonucleotide metabolic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009263",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0009263",
            "unique_facets": [
                "Class"
            ],
            "label": "deoxyribonucleotide biosynthetic process"
        }
    ],
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    "pub_syn": [
        {
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                "label": "2'-deoxyribonucleotide biosynthesis",
                "type": ""
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        },
        {
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                "label": "2'-deoxyribonucleotide formation",
                "type": ""
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                    "label": ""
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                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2'-deoxyribonucleotide synthesis",
                "type": ""
            },
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                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
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                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2'-deoxyribonucleotide anabolism",
                "type": ""
            },
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        }
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51 - 2'-deoxyribonucleotide metabolic process [GO_0009394]

The chemical reactions and pathways involving a 2’-deoxyribonucleotide, a compound consisting of 2’-deoxyribonucleoside (a base linked to a 2’-deoxyribose sugar) esterified with a phosphate group at either the 3’ or 5’-hydroxyl group of the sugar.

Open 2’-deoxyribonucleotide metabolic process in VFB

Term Information

  • ID: GO_0009394
  • Name: 2’-deoxyribonucleotide metabolic process
  • Definition: The chemical reactions and pathways involving a 2’-deoxyribonucleotide, a compound consisting of 2’-deoxyribonucleoside (a base linked to a 2’-deoxyribose sugar) esterified with a phosphate group at either the 3’ or 5’-hydroxyl group of the sugar.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0009394",
            "symbol": "",
            "types": [
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                "Class"
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            "short_form": "GO_0009394",
            "unique_facets": [
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            ],
            "label": "2'-deoxyribonucleotide metabolic process"
        },
        "description": [
            "The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019692",
            "types": [
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                "Class"
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            "short_form": "GO_0019692",
            "unique_facets": [
                "Class"
            ],
            "label": "deoxyribose phosphate metabolic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009262",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0009262",
            "unique_facets": [
                "Class"
            ],
            "label": "deoxyribonucleotide metabolic process"
        }
    ],
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        {
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                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
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                "label": ""
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            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
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}

52 - 2',3'-cyclic GMP-AMP binding [GO_0061507]

Binding to 2’,3’ cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2’,5’ and 3’,5’ linkages.

Open 2’,3’-cyclic GMP-AMP binding in VFB

Term Information

  • ID: GO_0061507
  • Name: 2’,3’-cyclic GMP-AMP binding
  • Definition: Binding to 2’,3’ cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2’,5’ and 3’,5’ linkages.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0061507",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0061507",
            "unique_facets": [
                "Class"
            ],
            "label": "2',3'-cyclic GMP-AMP binding"
        },
        "description": [
            "Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0032559",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0032559",
            "unique_facets": [
                "Class"
            ],
            "label": "adenyl ribonucleotide binding"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140702",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0140702",
            "unique_facets": [
                "Class"
            ],
            "label": "cyclic GMP-AMP binding"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0032561",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0032561",
            "unique_facets": [
                "Class"
            ],
            "label": "guanyl ribonucleotide binding"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0043168",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0043168",
            "unique_facets": [
                "Class"
            ],
            "label": "anion binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2',5-3',5'-cyclic GMP-AMP binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
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                    "short_form": "Unattributed",
                    "unique_facets": [
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2',3'-cyclic GAMP binding",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
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                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "cyclic-GMP-AMP binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2',3'-cGAMP binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2',3' cyclic GAMP binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2',3' cGAMP binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

53 - 23S rRNA (adenine(1618)-N(6))-methyltransferase activity [GO_0052907]

Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.

Open 23S rRNA (adenine(1618)-N(6))-methyltransferase activity in VFB

Term Information

  • ID: GO_0052907
  • Name: 23S rRNA (adenine(1618)-N(6))-methyltransferase activity
  • Definition: Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0052907",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0052907",
            "unique_facets": [
                "Class"
            ],
            "label": "23S rRNA (adenine(1618)-N(6))-methyltransferase activity"
        },
        "description": [
            "Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008988",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0008988",
            "unique_facets": [
                "Class"
            ],
            "label": "rRNA (adenine-N6-)-methyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "rRNA large subunit methyltransferase F activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

54 - 2xENPP1 hydrolyzes FAD to FMN [GO_0004551]

Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides.

Open 2xENPP1 hydrolyzes FAD to FMN in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004551",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004551",
            "label": "2xENPP1 hydrolyzes FAD to FMN"
        },
        "description": [
            "Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016462",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016462",
            "label": "pyrophosphatase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "nucleotide diphosphatase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "nucleotide pyrophosphatase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "dinucleotide nucleotidohydrolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

55 - 2xPDKX:2xZn2+ phosphorylates PDX [GO_0008478]

Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5’-phosphate.

Open 2xPDKX:2xZn2+ phosphorylates PDX in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008478",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008478",
            "label": "2xPDKX:2xZn2+ phosphorylates PDX"
        },
        "description": [
            "Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016301",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016301",
            "label": "FN3KRP phosphorylates PsiAm, RibAm"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016773",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016773",
            "label": "phosphotransferase activity, alcohol group as acceptor"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ATP:pyridoxal 5'-phosphotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

56 - 2xPNPO:2xFMN oxidizes PXAP to PXLP [GO_0004733]

Catalysis of the reaction: pyridoxamine 5’-phosphate + H2O + O2 = pyridoxal 5’-phosphate + NH3 + hydrogen peroxide.

Open 2xPNPO:2xFMN oxidizes PXAP to PXLP in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004733",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004733",
            "label": "2xPNPO:2xFMN oxidizes PXAP to PXLP"
        },
        "description": [
            "Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016641",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016641",
            "label": "oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0042823",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0042823",
                "label": "pyridoxal phosphate biosynthetic process"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating)",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

57 - 2xPPCS ligates PPanK with Cys [GO_0004632]

Catalysis of the reaction: CTP + (R)-4’-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4’-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives.

Open 2xPPCS ligates PPanK with Cys in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004632",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004632",
            "label": "2xPPCS ligates PPanK with Cys"
        },
        "description": [
            "Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016881",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016881",
            "label": "acid-amino acid ligase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "phosphopantothenoylcysteine synthetase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "phosphopantothenate-cysteine ligase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "(R)-4'-phosphopantothenate:L-cysteine ligase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

58 - 2xTPK1:Mg2+ phosphorylates THMN [GO_0004788]

Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate.

Open 2xTPK1:Mg2+ phosphorylates THMN in VFB

Term Information

  • ID: GO_0004788
  • Name: 2xTPK1:Mg2+ phosphorylates THMN
  • Definition: Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004788",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004788",
            "unique_facets": [
                "Class"
            ],
            "label": "2xTPK1:Mg2+ phosphorylates THMN"
        },
        "description": [
            "Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016778",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016778",
            "unique_facets": [
                "Class"
            ],
            "label": "diphosphotransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "thiamine pyrophosphokinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "thiamin pyrophosphokinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "thiamin diphosphokinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "TPTase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

59 - 2xTRAP hydrolyzes FMN to RIB [GO_0003993]

Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.

Open 2xTRAP hydrolyzes FMN to RIB in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003993",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003993",
            "label": "2xTRAP hydrolyzes FMN to RIB"
        },
        "description": [
            "Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016791",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016791",
            "label": "phosphatase activity"
        }
    ],
    "relationships": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acid phosphohydrolase activity",
                "type": ""
            },
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                    "symbol": "",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

60 - 3 iron, 4 sulfur cluster binding [GO_0051538]

Binding to a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.

Open 3 iron, 4 sulfur cluster binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0051538",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0051538",
            "label": "3 iron, 4 sulfur cluster binding"
        },
        "description": [
            "Binding to a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0051536",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0051536",
            "label": "iron-sulfur cluster binding"
        }
    ],
    "relationships": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "iron-sulfur cluster 3Fe-4S binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
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                "scope": "has_exact_synonym",
                "label": "3Fe-4S cluster binding",
                "type": ""
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            "pub": {
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "iron-sulphur cluster 3Fe-4S binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3 iron, 4 sulphur cluster binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3 Fe 4 S cluster binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "triiron tetrasulfide cluster binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "triiron tetrasulphide cluster binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

61 - 3-dehydrosphinganine reductase activity [GO_0047560]

Catalysis of the reaction: NADP+ + sphinganine = 3-dehydrosphinganine + H+ + NADPH.

Open 3-dehydrosphinganine reductase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0047560",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0047560",
            "label": "3-dehydrosphinganine reductase activity"
        },
        "description": [
            "Catalysis of the reaction: NADP+ + sphinganine = 3-dehydrosphinganine + H+ + NADPH."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016616",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016616",
            "label": "RDH11 reduces RBP2:atRAL to RBP2:atROL"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "3-ketosphinganine reductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

62 - 3-demethoxyubiquinol 3-hydroxylase activity [GO_0008682]

Catalysis of the reaction: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = A + a 3-demethylubiquinol + H2O.

Open 3-demethoxyubiquinol 3-hydroxylase activity in VFB

Term Information

  • ID: GO_0008682
  • Name: 3-demethoxyubiquinol 3-hydroxylase activity
  • Definition: Catalysis of the reaction: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = A + a 3-demethylubiquinol + H2O.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008682",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008682",
            "unique_facets": [
                "Class"
            ],
            "label": "3-demethoxyubiquinol 3-hydroxylase activity"
        },
        "description": [
            "Catalysis of the reaction: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = A + a 3-demethylubiquinol + H2O."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004497",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004497",
            "unique_facets": [
                "Class"
            ],
            "label": "CYP4F8 19-hydroxylates PGH2"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016705",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016705",
            "unique_facets": [
                "Class"
            ],
            "label": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

63 - 3-hydroxyacyl-CoA dehydratase activity [GO_0018812]

Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA).

Open 3-hydroxyacyl-CoA dehydratase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0018812",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0018812",
            "label": "3-hydroxyacyl-CoA dehydratase activity"
        },
        "description": [
            "Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016836",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016836",
            "label": "hydro-lyase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

64 - 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA [GO_0003988]

Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.

Open 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003988",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003988",
            "label": "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA"
        },
        "description": [
            "Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016408",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016408",
            "label": "C-acyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "2-keto-acyl thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "label": ""
                },
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                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-ketothiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "2-methylacetoacetyl-CoA thiolase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "KAT",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "oxoacyl-coenzyme A thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acetyl-CoA acyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "beta-ketoadipyl coenzyme A thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acetoacetyl-CoA beta-ketothiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-ketoacyl-CoA thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "thiolase I",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "pro-3-ketoacyl-CoA thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ketoacyl-coenzyme A thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "beta-ketothiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-oxoacyl-coenzyme A thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "6-oxoacyl-CoA thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "long-chain 3-oxoacyl-CoA thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-ketoacyl coenzyme A thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-oxoacyl-CoA thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ketoacyl-CoA acyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-ketoacyl thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "beta-ketoacyl coenzyme A thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "beta-ketoacyl-CoA thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "beta-ketoadipyl-CoA thiolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

65 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity [GO_0003863]

Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2.

Open 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003863",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003863",
            "label": "3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity"
        },
        "description": [
            "Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016624",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016624",
            "label": "oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"
        }
    ],
    "relationships": [],
    "xrefs": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "alpha-ketoacid dehydrogenase activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

66 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [GO_0004315]

Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].

Open 3-oxoacyl-[acyl-carrier-protein] synthase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004315",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004315",
            "label": "3-oxoacyl-[acyl-carrier-protein] synthase activity"
        },
        "description": [
            "Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004312",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004312",
            "label": "acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "beta-ketoacyl-acyl-carrier-protein synthase II activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "label": ""
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-oxoacyl-ACP synthase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-oxoacyl-[acyl-carrier protein] synthase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ketoacyl-ACP synthase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "3-oxoacyl-acyl carrier protein synthase I activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

67 - 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity [GO_0010420]

Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+. Note that the polyprenyl sidechain substrate for this reaction has a different number of prenyl units in different organisms (for example, ubiquinone-6 in Saccharomyces, ubiquinone- 9 in rat and ubiquinone-10 in human), and thus the natural substrate for the enzymes from different organisms has a different number of prenyl units. However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units.

Open 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity in VFB

Term Information

  • ID: GO_0010420
  • Name: 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity
  • Definition: Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+.
  • Synonyms:
  • Type:
  • Comment: Note that the polyprenyl sidechain substrate for this reaction has a different number of prenyl units in different organisms (for example, ubiquinone-6 in Saccharomyces, ubiquinone- 9 in rat and ubiquinone-10 in human), and thus the natural substrate for the enzymes from different organisms has a different number of prenyl units. However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units.

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0010420",
            "symbol": "",
            "types": [
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                "has_subClass"
            ],
            "short_form": "GO_0010420",
            "unique_facets": [
                "Class"
            ],
            "label": "3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity"
        },
        "description": [
            "Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+."
        ],
        "comment": [
            "Note that the polyprenyl sidechain substrate for this reaction has a different number of prenyl units in different organisms (for example, ubiquinone-6 in Saccharomyces, ubiquinone- 9 in rat and ubiquinone-10 in human), and thus the natural substrate for the enzymes from different organisms has a different number of prenyl units. However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units."
        ]
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008757",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0008757",
            "unique_facets": [
                "Class"
            ],
            "label": "S-adenosylmethionine-dependent methyltransferase activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0006744",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0006744",
                "unique_facets": [
                    "Class"
                ],
                "label": "ubiquinone biosynthetic process"
            }
        }
    ],
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        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "polyprenyldihydroxybenzoate methyltransferase activity",
                "type": ""
            },
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                    ],
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                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

68 - 3,4-dihydroxyphenylacetaldehyde synthase activity [GO_0106425]

Catalysis of the reaction: L-dopa + O2 + H2O + H+ = 3,4-dihydroxyphenylacetaldehyde + CO2 + NH(4)+ + H2O2.

Open 3,4-dihydroxyphenylacetaldehyde synthase activity in VFB

Term Information

  • ID: GO_0106425
  • Name: 3,4-dihydroxyphenylacetaldehyde synthase activity
  • Definition: Catalysis of the reaction: L-dopa + O2 + H2O + H+ = 3,4-dihydroxyphenylacetaldehyde + CO2 + NH(4)+ + H2O2.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0106425",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0106425",
            "unique_facets": [
                "Class"
            ],
            "label": "3,4-dihydroxyphenylacetaldehyde synthase activity"
        },
        "description": [
            "Catalysis of the reaction: L-dopa + O2 + H2O + H+ = 3,4-dihydroxyphenylacetaldehyde + CO2 + NH(4)+ + H2O2."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016831",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016831",
            "unique_facets": [
                "Class"
            ],
            "label": "PXLP-K333-GADL1 decarboxylates CSA to HTAU"
        }
    ],
    "relationships": [],
    "xrefs": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "DHPAA synthase",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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            }
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                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

69 - 3'-5' DNA/RNA helicase activity [GO_0033679]

Unwinding of a DNA/RNA duplex in the 3’ to 5’ direction, driven by ATP hydrolysis.

Open 3’-5’ DNA/RNA helicase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0033679",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0033679",
            "label": "3'-5' DNA/RNA helicase activity"
        },
        "description": [
            "Unwinding of a DNA/RNA duplex in the 3' to 5' direction, driven by ATP hydrolysis."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0033677",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0033677",
            "label": "DNA/RNA helicase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATP-dependent 3' to 5' DNA/RNA helicase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATP-dependent 3'-5' DNA/RNA helicase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3' to 5' DNA/RNA helicase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
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                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                "symbol": "",
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
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        }
    ]
}

70 - 3'-5' exonuclease activity [GO_0008408]

Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3’ end.

Open 3’-5’ exonuclease activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008408",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008408",
            "label": "3'-5' exonuclease activity"
        },
        "description": [
            "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004527",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004527",
            "label": "exonuclease activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3'-5'-exonuclease activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

71 - 3'-5' RNA helicase activity [GO_0034458]

Unwinding of an RNA helix in the 3’ to 5’ direction, driven by ATP hydrolysis.

Open 3’-5’ RNA helicase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0034458",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0034458",
            "label": "3'-5' RNA helicase activity"
        },
        "description": [
            "Unwinding of an RNA helix in the 3' to 5' direction, driven by ATP hydrolysis."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0003724",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003724",
            "label": "Cap-bound mRNA is activated by helicases"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATP-dependent 3'-5' RNA helicase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATP-dependent 3' to 5' RNA helicase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3' to 5' RNA helicase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
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                "DOI": ""
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    "def_pubs": [
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

72 - 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing [GO_0044748]

Catalysis of the sequential cleavage of mononucleotides from a free 3’ terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA.

Open 3’-5’-exoribonuclease activity involved in mature miRNA 3’-end processing in VFB

Term Information

  • ID: GO_0044748
  • Name: 3’-5’-exoribonuclease activity involved in mature miRNA 3’-end processing
  • Definition: Catalysis of the sequential cleavage of mononucleotides from a free 3’ terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0044748",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0044748",
            "unique_facets": [
                "Class"
            ],
            "label": "3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing"
        },
        "description": [
            "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0000175",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0000175",
            "unique_facets": [
                "Class"
            ],
            "label": "nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0044747",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0044747",
                "unique_facets": [
                    "Class"
                ],
                "label": "pre-miRNA 3'-end processing"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "exonucleolytic trimming to generate 3' end of miRNA",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "types": [
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                    "label": ""
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                "PubMed": "",
                "DOI": ""
            }
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                "label": ""
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            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

73 - 3'-flap endonuclease activity [GO_0048257]

Catalysis of the cleavage of a 3’ flap structure in DNA, but not other DNA structures; processes the 3’ ends of Okazaki fragments in lagging strand DNA synthesis.

Open 3’-flap endonuclease activity in VFB

Term Information

  • ID: GO_0048257
  • Name: 3’-flap endonuclease activity
  • Definition: Catalysis of the cleavage of a 3’ flap structure in DNA, but not other DNA structures; processes the 3’ ends of Okazaki fragments in lagging strand DNA synthesis.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0048257",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0048257",
            "unique_facets": [
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            ],
            "label": "3'-flap endonuclease activity"
        },
        "description": [
            "Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016889",
            "types": [
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                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016889",
            "unique_facets": [
                "Class"
            ],
            "label": "DNA endonuclease activity, producing 3'-phosphomonoesters"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0048256",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0048256",
            "unique_facets": [
                "Class"
            ],
            "label": "flap endonuclease activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3' flap endonuclease activity",
                "type": ""
            },
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                    "short_form": "Unattributed",
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                    "label": ""
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                "PubMed": "",
                "DOI": ""
            }
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                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
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        }
    ]
}

74 - 3'-nucleotidase activity [GO_0008254]

Catalysis of the reaction: a 3’-ribonucleotide + H2O = a ribonucleoside + phosphate.

Open 3’-nucleotidase activity in VFB

Term Information

  • ID: GO_0008254
  • Name: 3’-nucleotidase activity
  • Definition: Catalysis of the reaction: a 3’-ribonucleotide + H2O = a ribonucleoside + phosphate.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008254",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008254",
            "unique_facets": [
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            ],
            "label": "3'-nucleotidase activity"
        },
        "description": [
            "Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008252",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0008252",
            "unique_facets": [
                "Class"
            ],
            "label": "nucleotidase activity"
        }
    ],
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                "scope": "has_exact_synonym",
                "label": "3' nucleotidase activity",
                "type": ""
            },
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                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "3'-ribonucleotidase activity",
                "type": ""
            },
            "pub": {
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                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
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                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

75 - 3'-phospho-5'-adenylyl sulfate transmembrane transport [GO_1902559]

The process in which 3’-phospho-5’-adenylyl sulfate is transported across a membrane.

Open 3’-phospho-5’-adenylyl sulfate transmembrane transport in VFB

Term Information

  • ID: GO_1902559
  • Name: 3’-phospho-5’-adenylyl sulfate transmembrane transport
  • Definition: The process in which 3’-phospho-5’-adenylyl sulfate is transported across a membrane.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_1902559",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1902559",
            "unique_facets": [
                "Class"
            ],
            "label": "3'-phospho-5'-adenylyl sulfate transmembrane transport"
        },
        "description": [
            "The process in which 3'-phospho-5'-adenylyl sulfate is transported across a membrane."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0046963",
            "types": [
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                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0046963",
            "unique_facets": [
                "Class"
            ],
            "label": "3'-phosphoadenosine 5'-phosphosulfate transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_1901679",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_1901679",
            "unique_facets": [
                "Class"
            ],
            "label": "nucleotide transmembrane transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0072530",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0072530",
            "unique_facets": [
                "Class"
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            "label": "purine-containing compound transmembrane transport"
        }
    ],
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        {
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                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

76 - 3'-phosphoadenosine 5'-phosphosulfate transport [GO_0046963]

The directed movement of 3’-phosphoadenosine 5’-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5’-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Open 3’-phosphoadenosine 5’-phosphosulfate transport in VFB

Term Information

  • ID: GO_0046963
  • Name: 3’-phosphoadenosine 5’-phosphosulfate transport
  • Definition: The directed movement of 3’-phosphoadenosine 5’-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5’-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0046963",
            "symbol": "",
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                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0046963",
            "unique_facets": [
                "Class"
            ],
            "label": "3'-phosphoadenosine 5'-phosphosulfate transport"
        },
        "description": [
            "The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0072348",
            "types": [
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                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0072348",
            "unique_facets": [
                "Class"
            ],
            "label": "sulfur compound transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0051503",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0051503",
            "unique_facets": [
                "Class"
            ],
            "label": "adenine nucleotide transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015868",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0015868",
            "unique_facets": [
                "Class"
            ],
            "label": "purine ribonucleotide transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015711",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0015711",
            "unique_facets": [
                "Class"
            ],
            "label": "organic anion transport"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3'-phosphoadenosine 5'-phosphosulphate transport",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
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                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
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                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adenosine 3'-phosphate 5'-phosphosulfate transport",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "PAPS transport",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "unique_facets": [
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                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
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            }
        }
    ],
    "def_pubs": [
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                "short_form": "Unattributed",
                "unique_facets": [
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                "label": ""
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    ]
}

77 - 3'-tRNA processing endoribonuclease activity [GO_0042781]

Catalysis of the endonucleolytic cleavage of RNA, removing extra 3’ nucleotides from tRNA precursor, generating 3’ termini of tRNAs. A 3’-hydroxy group is left at the tRNA terminus and a 5’-phosphoryl group is left at the trailer molecule.

Open 3’-tRNA processing endoribonuclease activity in VFB

Term Information

  • ID: GO_0042781
  • Name: 3’-tRNA processing endoribonuclease activity
  • Definition: Catalysis of the endonucleolytic cleavage of RNA, removing extra 3’ nucleotides from tRNA precursor, generating 3’ termini of tRNAs. A 3’-hydroxy group is left at the tRNA terminus and a 5’-phosphoryl group is left at the trailer molecule.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
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            "short_form": "GO_0042781",
            "unique_facets": [
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            ],
            "label": "3'-tRNA processing endoribonuclease activity"
        },
        "description": [
            "Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140101",
            "types": [
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                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0140101",
            "unique_facets": [
                "Class"
            ],
            "label": "catalytic activity, acting on a tRNA"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016891",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016891",
            "unique_facets": [
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            ],
            "label": "RNA endonuclease activity, producing 5'-phosphomonoesters"
        }
    ],
    "relationships": [
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                "iri": "http://purl.obolibrary.org/obo/GO_0042780",
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                    "has_subClass"
                ],
                "short_form": "GO_0042780",
                "unique_facets": [
                    "Class"
                ],
                "label": "tRNA 3'-end processing"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "RNase Z activity",
                "type": ""
            },
            "pub": {
                "core": {
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        },
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                "label": "tRNA 3' endonuclease activity",
                "type": ""
            },
            "pub": {
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                    "short_form": "Unattributed",
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                    "label": ""
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                "FlyBase": "",
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                "DOI": ""
            }
        },
        {
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                "label": "3' tRNA processing endoribonuclease activity",
                "type": ""
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            "pub": {
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                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
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        },
        {
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                "label": "3' tRNase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "unique_facets": [
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                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "ribonuclease Z activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
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                    "label": ""
                },
                "FlyBase": "",
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                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "tRNA 3 endonuclease activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
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                    "label": ""
                },
                "FlyBase": "",
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            }
        }
    ],
    "def_pubs": []
}

78 - 3'-tyrosyl-DNA phosphodiesterase activity [GO_0017005]

Catalysis of the hydrolysis of 3’-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA. See also the molecular function term ‘DNA topoisomerase type I activity ; GO:0003917’.

Open 3’-tyrosyl-DNA phosphodiesterase activity in VFB

Term Information

  • ID: GO_0017005
  • Name: 3’-tyrosyl-DNA phosphodiesterase activity
  • Definition: Catalysis of the hydrolysis of 3’-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.
  • Synonyms:
  • Type:
  • Comment: See also the molecular function term ‘DNA topoisomerase type I activity ; GO:0003917’.

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0017005",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0017005",
            "unique_facets": [
                "Class"
            ],
            "label": "3'-tyrosyl-DNA phosphodiesterase activity"
        },
        "description": [
            "Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA."
        ],
        "comment": [
            "See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'."
        ]
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0070259",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0070259",
            "unique_facets": [
                "Class"
            ],
            "label": "tyrosyl-DNA phosphodiesterase activity"
        }
    ],
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                "unique_facets": [
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                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

79 - 3',2'-cyclic GMP-AMP binding [GO_0140704]

Binding to 3’,2’ cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3’,5’ and 2’,5’ linkages.

Open 3’,2’-cyclic GMP-AMP binding in VFB

Term Information

  • ID: GO_0140704
  • Name: 3’,2’-cyclic GMP-AMP binding
  • Definition: Binding to 3’,2’ cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3’,5’ and 2’,5’ linkages.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0140704",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140704",
            "unique_facets": [
                "Class"
            ],
            "label": "3',2'-cyclic GMP-AMP binding"
        },
        "description": [
            "Binding to 3',2' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 2',5' linkages."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0043168",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0043168",
            "unique_facets": [
                "Class"
            ],
            "label": "anion binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3',2'-cyclic GAMP binding",
                "type": ""
            },
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                    "symbol": "",
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                "DOI": ""
            }
        },
        {
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                "label": "3',2'-cGAMP binding",
                "type": ""
            },
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                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3',2' cyclic-GMP-AMP binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "unique_facets": [
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                    "label": ""
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                "PubMed": "",
                "DOI": ""
            }
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                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

80 - 3',2'-cyclic GMP-AMP synthase activity [GO_0140700]

Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3’-5’)A-P(2’-5’) (cyclic 3’,2’ GAMP).

Open 3’,2’-cyclic GMP-AMP synthase activity in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0140700",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140700",
            "label": "3',2'-cyclic GMP-AMP synthase activity"
        },
        "description": [
            "Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(2'-5') (cyclic 3',2' GAMP)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140699",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140699",
            "label": "cyclic GMP-AMP synthase activity"
        }
    ],
    "relationships": [],
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    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3',2' cyclic-GMP-AMP synthase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "DOI": ""
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        },
        {
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                "scope": "has_exact_synonym",
                "label": "3',2'-cyclic GAMP synthase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
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                "DOI": ""
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                "short_form": "Unattributed",
                "label": ""
            },
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        }
    ]
}

81 - 4 iron, 4 sulfur cluster binding [GO_0051539]

Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.

Open 4 iron, 4 sulfur cluster binding in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0051539",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0051539",
            "label": "4 iron, 4 sulfur cluster binding"
        },
        "description": [
            "Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0051536",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0051536",
            "label": "iron-sulfur cluster binding"
        }
    ],
    "relationships": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "4 iron, 4 sulphur cluster binding",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "tetrairon tetrasulphide cluster binding",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "4 Fe 4 S cluster binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "4Fe-4S cluster binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "iron-sulfur cluster 4Fe-4S binding",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
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                "scope": "has_exact_synonym",
                "label": "iron-sulphur cluster 4Fe-4S binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "tetrairon tetrasulfide cluster binding",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                "symbol": "",
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                    "pub"
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
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    ]
}

82 - 4-hydroxybenzoate decaprenyltransferase activity [GO_0002083]

Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.

Open 4-hydroxybenzoate decaprenyltransferase activity in VFB

Term Information

  • ID: GO_0002083
  • Name: 4-hydroxybenzoate decaprenyltransferase activity
  • Definition: Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0002083",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0002083",
            "unique_facets": [
                "Class"
            ],
            "label": "4-hydroxybenzoate decaprenyltransferase activity"
        },
        "description": [
            "Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0002094",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0002094",
            "unique_facets": [
                "Class"
            ],
            "label": "polyprenyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

83 - 4-hydroxyphenylpyruvate dioxygenase activity [GO_0003868]

Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2.

Open 4-hydroxyphenylpyruvate dioxygenase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003868",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003868",
            "label": "4-hydroxyphenylpyruvate dioxygenase activity"
        },
        "description": [
            "Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016702",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016702",
            "label": "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating)",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

84 - 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol [GO_0000253]

Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H+. Note that zymosterol is cholesta-8,24-dien-3-ol.

Open 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0000253",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0000253",
            "label": "4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol"
        },
        "description": [
            "Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H+."
        ],
        "comment": [
            "Note that zymosterol is cholesta-8,24-dien-3-ol."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016616",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016616",
            "label": "RDH11 reduces RBP2:atRAL to RBP2:atROL"
        }
    ],
    "relationships": [],
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        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-keto-steroid reductase activity",
                "type": ""
            },
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                    "symbol": "",
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        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "3beta-hydroxy-steroid:NADP+ 3-oxidoreductase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "DOI": ""
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        }
    ],
    "def_pubs": []
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85 - 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol [GO_0000254]

Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H+ + 3 O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O. Note that zymosterol is cholesta-8,24-dien-3-ol.

Open 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0000254",
            "symbol": "",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0000254",
            "label": "4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol"
        },
        "description": [
            "Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H+ + 3 O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O."
        ],
        "comment": [
            "Note that zymosterol is cholesta-8,24-dien-3-ol."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016716",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016716",
            "label": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen"
        }
    ],
    "relationships": [],
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    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "methylsterol hydroxylase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

86 - 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O [GO_0008124]

Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.

Open 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008124",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008124",
            "label": "4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O"
        },
        "description": [
            "Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016836",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016836",
            "label": "hydro-lyase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "4a-hydroxytetrahydrobiopterin dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "pterin-4a-carbinolamine dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "pterin-4-alpha-carbinolamine dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "pterin-4alpha-carbinolamine dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

87 - 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane [GO_0005548]

Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.

Open 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0005548",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005548",
            "label": "4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane"
        },
        "description": [
            "Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0005319",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005319",
            "label": "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0015914",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0015914",
                "label": "phospholipid transport"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

88 - 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HpEPE to 18(R)-RvE2 [GO_0003959]

Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.

Open 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HpEPE to 18(R)-RvE2 in VFB

Term Information

  • ID: GO_0003959
  • Name: 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HpEPE to 18(R)-RvE2
  • Definition: Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003959",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003959",
            "unique_facets": [
                "Class"
            ],
            "label": "5-HEDH dehydrogenates 5(S)-Hp-18(R)-HpEPE to 18(R)-RvE2"
        },
        "description": [
            "Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016651",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016651",
            "unique_facets": [
                "Class"
            ],
            "label": "RNLS:FAD oxidises dh-beta-NAD to NAD+"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "NADPH-dehydrogenase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

89 - 5-hydroxy-L-tryptophan decarboxylase activity [GO_0036467]

Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin.

Open 5-hydroxy-L-tryptophan decarboxylase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0036467",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0036467",
            "label": "5-hydroxy-L-tryptophan decarboxylase activity"
        },
        "description": [
            "Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004058",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004058",
            "label": "aromatic-L-amino-acid decarboxylase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

90 - 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi [GO_0004637]

Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H+ + phosphate.

Open 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004637",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004637",
            "label": "5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi"
        },
        "description": [
            "Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H+ + phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016879",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016879",
            "label": "ligase activity, forming carbon-nitrogen bonds"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "phosphoribosylglycineamide synthetase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

91 - 5,10-methylenetetrahydrofolate-dependent methyltransferase activity [GO_0042083]

Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.

Open 5,10-methylenetetrahydrofolate-dependent methyltransferase activity in VFB

Term Information

  • ID: GO_0042083
  • Name: 5,10-methylenetetrahydrofolate-dependent methyltransferase activity
  • Definition: Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0042083",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0042083",
            "unique_facets": [
                "Class"
            ],
            "label": "5,10-methylenetetrahydrofolate-dependent methyltransferase activity"
        },
        "description": [
            "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008168",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008168",
            "unique_facets": [
                "Class"
            ],
            "label": "COMT transfers Met to DOPAC to form HVA"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

92 - 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate [GO_0004157]

Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate.

Open 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004157",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004157",
            "label": "5,6-dihydrothymine + H2O => beta-ureidoisobutyrate"
        },
        "description": [
            "Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016812",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016812",
            "label": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "hydantoinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

93 - 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity [GO_0140933]

Catalysis of the reaction: a 5’-end (N7-methyl 5’-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5’-end phospho-ribonucleoside in mRNA + N7-methyl-GDP + H+.

Open **5’-(N(7)-methylguanosine 5’-triphospho)-[mRNA] hydrolase activity** in VFB

Term Information

  • ID: GO_0140933
  • Name: 5’-(N(7)-methylguanosine 5’-triphospho)-[mRNA] hydrolase activity
  • Definition: Catalysis of the reaction: a 5’-end (N7-methyl 5’-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5’-end phospho-ribonucleoside in mRNA + N7-methyl-GDP + H+.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0140933",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140933",
            "unique_facets": [
                "Class"
            ],
            "label": "5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"
        },
        "description": [
            "Catalysis of the reaction: a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + N7-methyl-GDP + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140818",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140818",
            "unique_facets": [
                "Class"
            ],
            "label": "mRNA 5'-phosphatase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "m(7)GpppN-mRNA hydrolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

94 - 5'-3' exodeoxyribonuclease activity [GO_0035312]

Catalysis of the sequential cleavage of mononucleotides from a free 5’ terminus of a DNA molecule.

Open 5’-3’ exodeoxyribonuclease activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0035312",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0035312",
            "label": "5'-3' exodeoxyribonuclease activity"
        },
        "description": [
            "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016895",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016895",
            "label": "exodeoxyribonuclease activity, producing 5'-phosphomonoesters"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008409",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008409",
            "label": "EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

95 - 5'-3' exoribonuclease activity [GO_0004534]

Catalysis of the sequential cleavage of mononucleotides from a free 5’ terminus of an RNA molecule.

Open 5’-3’ exoribonuclease activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004534",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004534",
            "label": "5'-3' exoribonuclease activity"
        },
        "description": [
            "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008409",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008409",
            "label": "EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016896",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016896",
            "label": "exoribonuclease activity, producing 5'-phosphomonoesters"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

96 - 5'-3' RNA polymerase activity [GO_0034062]

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3’-end.

Open 5’-3’ RNA polymerase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0034062",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0034062",
            "label": "5'-3' RNA polymerase activity"
        },
        "description": [
            "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0097747",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0097747",
            "label": "RNA polymerase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "RNA polymerase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "C RNA formation factors",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

97 - 5'-deoxynucleotidase activity [GO_0002953]

Catalysis of the reaction:a 2’-deoxyribonucleoside 5’-monophosphate + H20=a 2’-deoxyribonucleoside + phosphate.

Open 5’-deoxynucleotidase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0002953",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0002953",
            "label": "5'-deoxynucleotidase activity"
        },
        "description": [
            "Catalysis of the reaction:a 2'-deoxyribonucleoside 5'-monophosphate + H20=a 2'-deoxyribonucleoside + phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016791",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016791",
            "label": "phosphatase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

98 - 5'-nucleotidase activity [GO_0008253]

Catalysis of the reaction: a 5’-ribonucleotide + H2O = a ribonucleoside + phosphate.

Open 5’-nucleotidase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008253",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008253",
            "label": "5'-nucleotidase activity"
        },
        "description": [
            "Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008252",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008252",
            "label": "nucleotidase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "5' nucleotidase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "thimidine monophosphate nucleotidase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

99 - 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol [GO_0004033]

Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+.

Open 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004033",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004033",
            "label": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol"
        },
        "description": [
            "Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016616",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016616",
            "label": "RDH11 reduces RBP2:atRAL to RBP2:atROL"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aldo-keto reductase (NADP+) activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aldo-keto reductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "alcohol dehydrogenase (NADP+) activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

100 - 5S rDNA binding [GO_0080084]

Binding to a 5S rDNA sequence, encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists.

Open 5S rDNA binding in VFB

Term Information

  • ID: GO_0080084
  • Name: 5S rDNA binding
  • Definition: Binding to a 5S rDNA sequence, encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0080084",
            "symbol": "",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0080084",
            "unique_facets": [
                "Class"
            ],
            "label": "5S rDNA binding"
        },
        "description": [
            "Binding to a 5S rDNA sequence, encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0000182",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0000182",
            "unique_facets": [
                "Class"
            ],
            "label": "rDNA binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

101 - 5S rRNA binding [GO_0008097]

Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome.

Open 5S rRNA binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008097",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008097",
            "label": "5S rRNA binding"
        },
        "description": [
            "Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019843",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0019843",
            "label": "rRNA binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

102 - 5S rRNA primary transcript binding [GO_0008098]

Binding to an unprocessed 5S ribosomal RNA transcript.

Open 5S rRNA primary transcript binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008098",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008098",
            "label": "5S rRNA primary transcript binding"
        },
        "description": [
            "Binding to an unprocessed 5S ribosomal RNA transcript."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008097",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008097",
            "label": "5S rRNA binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

103 - 6-phosphofructokinase activity [GO_0003872]

Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.

Open 6-phosphofructokinase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003872",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003872",
            "label": "6-phosphofructokinase activity"
        },
        "description": [
            "Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008443",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008443",
            "label": "phosphofructokinase activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0061615",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0061615",
                "label": "glycolytic process through fructose-6-phosphate"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "6-phosphofructokinase reduction",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "nucleotide triphosphate-dependent phosphofructokinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

104 - 6,7-dihydropteridine reductase activity [GO_0004155]

Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine. Note that this function was formerly EC:1.6.99.7.

Open 6,7-dihydropteridine reductase activity in VFB

Term Information

  • ID: GO_0004155
  • Name: 6,7-dihydropteridine reductase activity
  • Definition: Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine.
  • Synonyms:
  • Type:
  • Comment: Note that this function was formerly EC:1.6.99.7.

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004155",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004155",
            "unique_facets": [
                "Class"
            ],
            "label": "6,7-dihydropteridine reductase activity"
        },
        "description": [
            "Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine."
        ],
        "comment": [
            "Note that this function was formerly EC:1.6.99.7."
        ]
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016646",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016646",
            "unique_facets": [
                "Class"
            ],
            "label": "oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dihydropteridine reductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "dihydropteridine reduction",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "DHPR activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

105 - 7-beta-hydroxysteroid dehydrogenase (NADP+) activity [GO_0047022]

Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid.

Open 7-beta-hydroxysteroid dehydrogenase (NADP+) activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0047022",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0047022",
            "label": "7-beta-hydroxysteroid dehydrogenase (NADP+) activity"
        },
        "description": [
            "Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0033764",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0033764",
            "label": "steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "7beta-hydroxysteroid:NADP+ 7-oxidoreductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

106 - 7-methylguanosine cap hypermethylation [GO_0036261]

Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2’ position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.

Open 7-methylguanosine cap hypermethylation in VFB

Term Information

  • ID: GO_0036261
  • Name: 7-methylguanosine cap hypermethylation
  • Definition: Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2’ position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0036261",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0036261",
            "unique_facets": [
                "Class"
            ],
            "label": "7-methylguanosine cap hypermethylation"
        },
        "description": [
            "Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0036260",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0036260",
            "unique_facets": [
                "Class"
            ],
            "label": "RNA capping"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0001510",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0001510",
            "unique_facets": [
                "Class"
            ],
            "label": "RNA methylation"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "snoRNA capping",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

107 - 7-methylguanosine mRNA capping [GO_0006370]

Addition of the 7-methylguanosine cap to the 5’ end of a nascent messenger RNA transcript.

Open 7-methylguanosine mRNA capping in VFB

Term Information

  • ID: GO_0006370
  • Name: 7-methylguanosine mRNA capping
  • Definition: Addition of the 7-methylguanosine cap to the 5’ end of a nascent messenger RNA transcript.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0006370",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0006370",
            "unique_facets": [
                "Class"
            ],
            "label": "7-methylguanosine mRNA capping"
        },
        "description": [
            "Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009452",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0009452",
            "unique_facets": [
                "Class"
            ],
            "label": "7-methylguanosine RNA capping"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0006397",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0006397",
            "unique_facets": [
                "Class"
            ],
            "label": "mRNA processing"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "5'-end mRNA processing",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "5'-end processing",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "5' mRNA capping",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "5' end capping",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
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                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        }
    ],
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
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                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
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108 - 7-methylguanosine RNA capping [GO_0009452]

The sequence of enzymatic reactions by which the 5’ cap structure, an inverted 7-methylguanosine linked via a 5’-5’ triphosphate bridge (m7G(5’)ppp(5’)X) to the first transcribed residue, is added to a nascent transcript.

Open 7-methylguanosine RNA capping in VFB

Term Information

  • ID: GO_0009452
  • Name: 7-methylguanosine RNA capping
  • Definition: The sequence of enzymatic reactions by which the 5’ cap structure, an inverted 7-methylguanosine linked via a 5’-5’ triphosphate bridge (m7G(5’)ppp(5’)X) to the first transcribed residue, is added to a nascent transcript.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0009452",
            "symbol": "",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0009452",
            "unique_facets": [
                "Class"
            ],
            "label": "7-methylguanosine RNA capping"
        },
        "description": [
            "The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0036260",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0036260",
            "unique_facets": [
                "Class"
            ],
            "label": "RNA capping"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

109 - 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one [GO_0003854]

Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H+.

Open 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one in VFB

Term Information

  • ID: GO_0003854
  • Name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one
  • Definition: Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H+.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003854",
            "symbol": "",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0003854",
            "unique_facets": [
                "Class"
            ],
            "label": "7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one"
        },
        "description": [
            "Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "08f7a30",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0033764",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0033764",
            "unique_facets": [
                "Class"
            ],
            "label": "steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3-beta-hydroxy-D5-steroid dehydrogenase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "3beta-hydroxy steroid dehydrogenase/isomerase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

110 - 7S RNA binding [GO_0008312]

Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP).

Open 7S RNA binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008312",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008312",
            "label": "7S RNA binding"
        },
        "description": [
            "Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0003723",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003723",
            "label": "Exportin-5 recognizes 3' overhang of pre-miRNA"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

111 - 7SK snRNA binding [GO_0097322]

Binding to a 7SK small nuclear RNA (7SK snRNA).

Open 7SK snRNA binding in VFB

Term Information

  • ID: GO_0097322
  • Name: 7SK snRNA binding
  • Definition: Binding to a 7SK small nuclear RNA (7SK snRNA).
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0097322",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0097322",
            "unique_facets": [
                "Class"
            ],
            "label": "7SK snRNA binding"
        },
        "description": [
            "Binding to a 7SK small nuclear RNA (7SK snRNA)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0017069",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0017069",
            "unique_facets": [
                "Class"
            ],
            "label": "snRNA binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "7SK small nuclear RNA binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

112 - 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity [GO_0034039]

Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1’ glycosidic bond between the oxidized purine and the deoxyribose sugar.

Open 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity in VFB

Term Information

  • ID: GO_0034039
  • Name: 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
  • Definition: Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1’ glycosidic bond between the oxidized purine and the deoxyribose sugar.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0034039",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0034039",
            "unique_facets": [
                "Class"
            ],
            "label": "8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"
        },
        "description": [
            "Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008534",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0008534",
            "unique_facets": [
                "Class"
            ],
            "label": "Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "8-oxoG DNA N-glycosylase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

113 - A-type (transient outward) potassium channel activity [GO_0005250]

Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential.

Open A-type (transient outward) potassium channel activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0005250",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005250",
            "label": "A-type (transient outward) potassium channel activity"
        },
        "description": [
            "Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015271",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015271",
            "label": "outward rectifier potassium channel activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

114 - abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine [GO_0004000]

Catalysis of the reaction: adenosine + H2O = inosine + NH3.

Open abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004000",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004000",
            "label": "abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine"
        },
        "description": [
            "Catalysis of the reaction: adenosine + H2O = inosine + NH3."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016814",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016814",
            "label": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019239",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0019239",
            "label": "HRSP12 deaminates 2AA to 2OBUTA"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adenosine deaminase reaction",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "adenosine aminohydrolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

115 - ABC-type 3',5'-cyclic GMP transmembrane transporter activity [GO_1905948]

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3’,5’-cyclic GMP(in) = ADP + phosphate + 3’,5’-cyclic GMP(out).

Open ABC-type 3’,5’-cyclic GMP transmembrane transporter activity in VFB

Term Information

  • ID: GO_1905948
  • Name: ABC-type 3’,5’-cyclic GMP transmembrane transporter activity
  • Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3’,5’-cyclic GMP(in) = ADP + phosphate + 3’,5’-cyclic GMP(out).
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_1905948",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1905948",
            "unique_facets": [
                "Class"
            ],
            "label": "ABC-type 3',5'-cyclic GMP transmembrane transporter activity"
        },
        "description": [
            "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3',5'-cyclic GMP(in) = ADP + phosphate + 3',5'-cyclic GMP(out)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0001409",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0001409",
            "unique_facets": [
                "Class"
            ],
            "label": "guanine nucleotide transmembrane transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140359",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0140359",
            "unique_facets": [
                "Class"
            ],
            "label": "ABCC4 accumulation of dense granule contents"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008514",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0008514",
            "unique_facets": [
                "Class"
            ],
            "label": "Growing HA is extruded from the cell by ABCC5"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0005346",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0005346",
            "unique_facets": [
                "Class"
            ],
            "label": "purine ribonucleotide transmembrane transporter activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATP-dependent 3',5'-cyclic GMP transmembrane transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "3',5'-cyclic GMP transmembrane-transporting ATPase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATPase-coupled cGMP transmembrane transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
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                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
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                "scope": "has_related_synonym",
                "label": "ATPase-coupled 3',5'-cyclic GMP transmembrane transporter activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "short_form": "Unattributed",
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                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

116 - ABC-type fatty-acyl-CoA transporter activity [GO_0015607]

Catalysis of the reaction ATP + H2O + fatty acyl CoA(Side 1) <=> ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it.

Open ABC-type fatty-acyl-CoA transporter activity in VFB

VFB Term Json

{
    "term": {
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            "iri": "http://purl.obolibrary.org/obo/GO_0015607",
            "symbol": "",
            "types": [
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                "Class"
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            "short_form": "GO_0015607",
            "label": "ABC-type fatty-acyl-CoA transporter activity"
        },
        "description": [
            "Catalysis of the reaction ATP + H2O + fatty acyl CoA(Side 1) <=> ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0042887",
            "types": [
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                "Class"
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            "short_form": "GO_0042887",
            "label": "amide transmembrane transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_1901682",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1901682",
            "label": "sulfur compound transmembrane transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0071077",
            "types": [
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                "Class"
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            "short_form": "GO_0071077",
            "label": "adenosine 3',5'-bisphosphate transmembrane transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0034040",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0034040",
            "label": "ATPase-coupled lipid transmembrane transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140359",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140359",
            "label": "ABC-type transporter activity"
        }
    ],
    "relationships": [
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                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0015916",
                "types": [
                    "Entity",
                    "Class"
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                "short_form": "GO_0015916",
                "label": "fatty-acyl-CoA transport"
            }
        }
    ],
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    "pub_syn": [
        {
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                "scope": "has_broad_synonym",
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                "type": ""
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                    "label": ""
                },
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                "DOI": ""
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        },
        {
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                "type": ""
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                    "label": ""
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                "PubMed": "",
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            }
        },
        {
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                "scope": "has_exact_synonym",
                "label": "ABC-type fatty-acyl-CoA transporter",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
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        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "fatty acyl CoA transporter activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "short_form": "Unattributed",
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                },
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                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

117 - ABC-type guanine transporter activity [GO_0008558]

Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in).

Open ABC-type guanine transporter activity in VFB

Term Information

  • ID: GO_0008558
  • Name: ABC-type guanine transporter activity
  • Definition: Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in).
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008558",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008558",
            "unique_facets": [
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            "label": "ABC-type guanine transporter activity"
        },
        "description": [
            "Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140359",
            "types": [
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                "Class",
                "has_subClass"
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            "short_form": "GO_0140359",
            "unique_facets": [
                "Class"
            ],
            "label": "ABCC4 accumulation of dense granule contents"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015208",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0015208",
            "unique_facets": [
                "Class"
            ],
            "label": "guanine transmembrane transporter activity"
        }
    ],
    "relationships": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ATPase-coupled guanine transmembrane transporter activity",
                "type": ""
            },
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                "DOI": ""
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        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ATP-dependent guanine transmembrane transporter activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
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                    "label": ""
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        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "guanine ABC transporter",
                "type": ""
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                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "guanine-transporting ATPase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
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                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

118 - ABC-type polyamine transporter activity [GO_0015417]

Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in).

Open ABC-type polyamine transporter activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0015417",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015417",
            "label": "ABC-type polyamine transporter activity"
        },
        "description": [
            "Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140359",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140359",
            "label": "ABC-type transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015203",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015203",
            "label": "polyamine transmembrane transporter activity"
        }
    ],
    "relationships": [],
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    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "spermidine porter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
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                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "polyamine-importing ATPase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "polyamine porter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ATP-dependent polyamine transmembrane transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "spermidine-importing ATPase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ATPase-coupled polyamine transmembrane transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "ATPase-coupled spermidine transmembrane transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

119 - ABC-type transporter activity [GO_0140359]

Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.

Open ABC-type transporter activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0140359",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140359",
            "label": "ABC-type transporter activity"
        },
        "description": [
            "Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0042626",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0042626",
            "label": "PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12"
        }
    ],
    "relationships": [],
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        {
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                "label": "ATP binding cassette transporter",
                "type": ""
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                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ABC-type efflux permease activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATP-binding cassette (ABC) transporter activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ABC-type efflux porter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ABC-type transmembrane transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ABC transporter",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATP-binding cassette transporter",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ABC-type uptake permease activity",
                "type": ""
            },
            "pub": {
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                    "short_form": "Unattributed",
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                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

120 - ABC-type xenobiotic transporter activity [GO_0008559]

Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).

Open ABC-type xenobiotic transporter activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008559",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008559",
            "label": "ABC-type xenobiotic transporter activity"
        },
        "description": [
            "Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140359",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140359",
            "label": "ABC-type transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0042910",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0042910",
            "label": "xenobiotic transmembrane transporter activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "multidrug-resistance protein",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "multidrug resistance exporter",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "xenobiotic transmembrane transporting ATPase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATP-dependent xenobiotic transmembrane transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ATPase-coupled xenobiotic transmembrane transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "xenobiotic ABC transporter",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

121 - ABC7, mABC1 and mABC2 mediate heme transport [GO_0015439]

Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out).

Open ABC7, mABC1 and mABC2 mediate heme transport in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0015439",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015439",
            "label": "ABC7, mABC1 and mABC2 mediate heme transport"
        },
        "description": [
            "Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140359",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140359",
            "label": "ABC-type transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015232",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015232",
            "label": "SLC46A1 transports FeHM, heme from extracellular region to cytosol"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0035351",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0035351",
                "label": "heme transmembrane transport"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ATPase-coupled heme transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "protoheme IX ABC transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATP-dependent heme transmembrane transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "heme-transporting ATPase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "haem-transporting ATPase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ATPase-coupled heme transmembrane transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
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                "scope": "has_narrow_synonym",
                "label": "heme ABC transporter",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

122 - ABCC4 accumulation of dense granule contents [GO_0015662]

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.

Open ABCC4 accumulation of dense granule contents in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0015662",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015662",
            "label": "ABCC4 accumulation of dense granule contents"
        },
        "description": [
            "Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140358",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140358",
            "label": "P-type transmembrane transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0022853",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0022853",
            "label": "active ion transmembrane transporter activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "P-type ATPase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ion transmembrane transporter activity, phosphorylative mechanism",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

123 - AcCho is hydrolyzed to Cho and acetate by ACHE [GO_0003990]

Catalysis of the reaction: acetylcholine + H2O = choline + acetate.

Open AcCho is hydrolyzed to Cho and acetate by ACHE in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003990",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003990",
            "label": "AcCho is hydrolyzed to Cho and acetate by ACHE"
        },
        "description": [
            "Catalysis of the reaction: acetylcholine + H2O = choline + acetate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004104",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004104",
            "label": "cholinesterase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acetylcholine acetylhydrolase activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

124 - ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) [GO_0070573]

Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

Open ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0070573",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0070573",
            "label": "ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7)"
        },
        "description": [
            "Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008235",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008235",
            "label": "metalloexopeptidase activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016805",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016805",
            "label": "dipeptidase activity"
        }
    ],
    "relationships": [],
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    "def_pubs": [
        {
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

125 - ACE2 hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) [GO_0004181]

Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

Open ACE2 hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004181",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004181",
            "label": "ACE2 hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7)"
        },
        "description": [
            "Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008235",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008235",
            "label": "metalloexopeptidase activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004180",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004180",
            "label": "CNDP2:2Mn2+ dimer hydrolyses CysGly"
        }
    ],
    "relationships": [],
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

126 - acetaldehyde dehydrogenase (acetylating) activity [GO_0008774]

Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+.

Open acetaldehyde dehydrogenase (acetylating) activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008774",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008774",
            "label": "acetaldehyde dehydrogenase (acetylating) activity"
        },
        "description": [
            "Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016620",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016620",
            "label": "MscR reduces nitrosomycothiol to ammonia"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acylating acetaldehyde dehydrogenase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

127 - acetate CoA-transferase activity [GO_0008775]

Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.

Open acetate CoA-transferase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008775",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008775",
            "label": "acetate CoA-transferase activity"
        },
        "description": [
            "Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008410",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008410",
            "label": "CoA-transferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acetyl-CoA:acetoacetate CoA transferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

128 - acetate ester transmembrane transporter activity [GO_1901375]

Enables the transfer of an acetate ester from one side of a membrane to the other.

Open acetate ester transmembrane transporter activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_1901375",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1901375",
            "label": "acetate ester transmembrane transporter activity"
        },
        "description": [
            "Enables the transfer of an acetate ester from one side of a membrane to the other."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0022857",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0022857",
            "label": "An unknown carrier transports mitochondrial glyoxylate to the cytosol"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_1901374",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_1901374",
                "label": "acetate ester transport"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

129 - acetate ester transport [GO_1901374]

The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Open acetate ester transport in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_1901374",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1901374",
            "label": "acetate ester transport"
        },
        "description": [
            "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0071702",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0071702",
            "label": "organic substance transport"
        }
    ],
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

130 - acetate transmembrane transport [GO_0035433]

The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid. Note that this term is not intended for use in annotating lateral movement within membranes.

Open acetate transmembrane transport in VFB

Term Information

  • ID: GO_0035433
  • Name: acetate transmembrane transport
  • Definition: The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid.
  • Synonyms:
  • Type:
  • Comment: Note that this term is not intended for use in annotating lateral movement within membranes.

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0035433",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0035433",
            "unique_facets": [
                "Class"
            ],
            "label": "acetate transmembrane transport"
        },
        "description": [
            "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid."
        ],
        "comment": [
            "Note that this term is not intended for use in annotating lateral movement within membranes."
        ]
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_1905039",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_1905039",
            "unique_facets": [
                "Class"
            ],
            "label": "carboxylic acid transmembrane transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0006846",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0006846",
            "unique_facets": [
                "Class"
            ],
            "label": "acetate transport"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acetate membrane transport",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "short_form": "Unattributed",
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                        "pub"
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                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        }
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    "def_pubs": [
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
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                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

131 - acetate transmembrane transporter activity [GO_0015123]

Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.

Open acetate transmembrane transporter activity in VFB

Term Information

  • ID: GO_0015123
  • Name: acetate transmembrane transporter activity
  • Definition: Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0015123",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015123",
            "unique_facets": [
                "Class"
            ],
            "label": "acetate transmembrane transporter activity"
        },
        "description": [
            "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008028",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0008028",
            "unique_facets": [
                "Class"
            ],
            "label": "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_1901702",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_1901702",
            "unique_facets": [
                "Class"
            ],
            "label": "salt transmembrane transporter activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0035433",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0035433",
                "unique_facets": [
                    "Class"
                ],
                "label": "acetate transmembrane transport"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

132 - acetate transport [GO_0006846]

The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Open acetate transport in VFB

Term Information

  • ID: GO_0006846
  • Name: acetate transport
  • Definition: The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0006846",
            "symbol": "",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0006846",
            "unique_facets": [
                "Class"
            ],
            "label": "acetate transport"
        },
        "description": [
            "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0071705",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0071705",
            "unique_facets": [
                "Class"
            ],
            "label": "nitrogen compound transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015718",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0015718",
            "unique_facets": [
                "Class"
            ],
            "label": "monocarboxylic acid transport"
        }
    ],
    "relationships": [],
    "xrefs": [],
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    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

133 - acetate-CoA ligase activity [GO_0003987]

Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.

Open acetate-CoA ligase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003987",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003987",
            "label": "acetate-CoA ligase activity"
        },
        "description": [
            "Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016878",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016878",
            "label": "acid-thiol ligase activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016405",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016405",
            "label": "CoA-ligase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acetate to acetyl-CoA",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acetyl activating enzyme",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

134 - acetoacetyl-CoA reductase activity [GO_0018454]

Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.

Open acetoacetyl-CoA reductase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0018454",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0018454",
            "label": "acetoacetyl-CoA reductase activity"
        },
        "description": [
            "Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016616",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016616",
            "label": "RDH11 reduces RBP2:atRAL to RBP2:atROL"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "NADPH:acetoacetyl-CoA reductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

135 - acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH [GO_0004421]

Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H2O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H+. Note that this function was formerly EC:4.1.3.5.

Open acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004421",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004421",
            "label": "acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH"
        },
        "description": [
            "Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H2O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H+."
        ],
        "comment": [
            "Note that this function was formerly EC:4.1.3.5."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0046912",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0046912",
            "label": "acyltransferase activity, acyl groups converted into alkyl on transfer"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "3-hydroxy-3-methylglutaryl CoA synthetase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

136 - acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O [GO_0004312]

Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.

Open acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004312",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004312",
            "label": "acetyl-CoA + 7 malonyl-CoA + 14 NADHP + 14 H+ => palmitate + 7 CO2 + 14 NADP+ + 8 CoASH + 6 H2O"
        },
        "description": [
            "Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016747",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0016747",
            "label": "acyltransferase activity, transferring groups other than amino-acyl groups"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "fatty-acid synthase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

137 - Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA [GO_0004108]

Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group. Note that this function was formerly EC:4.1.3.7.

Open Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004108",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004108",
            "label": "Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA"
        },
        "description": [
            "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group."
        ],
        "comment": [
            "Note that this function was formerly EC:4.1.3.7."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0036440",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0036440",
            "label": "citrate synthase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "citric-condensing enzyme activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

138 - acetyl-CoA binding [GO_1905502]

Binding to acetyl-CoA, an acyl-CoA having acetyl as its S-acetyl component.

Open acetyl-CoA binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_1905502",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1905502",
            "label": "acetyl-CoA binding"
        },
        "description": [
            "Binding to acetyl-CoA, an acyl-CoA having acetyl as its S-acetyl component."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0043168",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0043168",
            "label": "anion binding"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0120227",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0120227",
            "label": "acyl-CoA binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acetyl-coenzyme A binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
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                "types": [
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

139 - acetyl-CoA C-acetyltransferase activity [GO_0003985]

Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA.

Open acetyl-CoA C-acetyltransferase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003985",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003985",
            "label": "acetyl-CoA C-acetyltransferase activity"
        },
        "description": [
            "Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016453",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016453",
            "label": "C-acetyltransferase activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0003988",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003988",
            "label": "3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "3-oxothiolase activity",
                "type": ""
            },
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                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

140 - acetylation-dependent protein binding [GO_0140033]

Binding to a protein upon acetylation of the target protein. This term should only be used when the binding is shown to require acetylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of acetylation. It may be that the acetylation causes a conformational change that allows binding of the protein to another region; this type of acetylation-dependent protein binding is valid for annotation to this term.

Open acetylation-dependent protein binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0140033",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140033",
            "label": "acetylation-dependent protein binding"
        },
        "description": [
            "Binding to a protein upon acetylation of the target protein."
        ],
        "comment": [
            "This term should only be used when the binding is shown to require acetylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of acetylation. It may be that the acetylation causes a conformational change that allows binding of the protein to another region; this type of acetylation-dependent protein binding is valid for annotation to this term."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140030",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140030",
            "label": "modification-dependent protein binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
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        {
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                "types": [
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

141 - acetylcholine binding [GO_0042166]

Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.

Open acetylcholine binding in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0042166",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0042166",
            "label": "acetylcholine binding"
        },
        "description": [
            "Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0043169",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0043169",
            "label": "cation binding"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0042165",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0042165",
            "label": "neurotransmitter binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
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        {
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

142 - acetylcholine receptor activator activity [GO_0030549]

Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased.

Open acetylcholine receptor activator activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0030549",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0030549",
            "label": "acetylcholine receptor activator activity"
        },
        "description": [
            "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0030546",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0030546",
            "label": "signaling receptor activator activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0030548",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0030548",
            "label": "acetylcholine receptor regulator activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002213",
                "label": "positively regulates",
                "type": "positively_regulates"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0015464",
                "types": [
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                    "Class"
                ],
                "short_form": "GO_0015464",
                "label": "acetylcholine receptor activity"
            }
        }
    ],
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                "symbol": "",
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

143 - acetylcholine receptor activity [GO_0015464]

Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. For nicotinic acetylcholine receptors that act as ion channels, instead use ‘acetylcholine-gated cation channel activity ; GO:0022848’.

Open acetylcholine receptor activity in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0015464",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015464",
            "label": "acetylcholine receptor activity"
        },
        "description": [
            "Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."
        ],
        "comment": [
            "For nicotinic acetylcholine receptors that act as ion channels, instead use 'acetylcholine-gated cation channel activity ; GO:0022848'."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0098960",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0098960",
            "label": "postsynaptic neurotransmitter receptor activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004888",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004888",
            "label": "Sphingomyelinase is activated by the NGF:p75NTR complex"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0007271",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0007271",
                "label": "synaptic transmission, cholinergic"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000051",
                "label": "has part",
                "type": "has_part"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0042166",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0042166",
                "label": "acetylcholine binding"
            }
        }
    ],
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                "types": [
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

144 - acetylcholine receptor binding [GO_0033130]

Binding to an acetylcholine receptor.

Open acetylcholine receptor binding in VFB

Term Information

  • ID: GO_0033130
  • Name: acetylcholine receptor binding
  • Definition: Binding to an acetylcholine receptor.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0033130",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0033130",
            "unique_facets": [
                "Class"
            ],
            "label": "acetylcholine receptor binding"
        },
        "description": [
            "Binding to an acetylcholine receptor."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0005102",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005102",
            "unique_facets": [
                "Class"
            ],
            "label": "signaling receptor binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

145 - acetylcholine receptor inhibitor activity [GO_0030550]

Binds to and stops, prevents or reduces the activity of an acetylcholine receptor.

Open acetylcholine receptor inhibitor activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0030550",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0030550",
            "label": "acetylcholine receptor inhibitor activity"
        },
        "description": [
            "Binds to and stops, prevents or reduces the activity of an acetylcholine receptor."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0030547",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0030547",
            "label": "signaling receptor inhibitor activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0030548",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0030548",
            "label": "acetylcholine receptor regulator activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002212",
                "label": "negatively regulates",
                "type": "negatively_regulates"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0015464",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0015464",
                "label": "acetylcholine receptor activity"
            }
        }
    ],
    "xrefs": [],
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    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

146 - acetylcholine receptor regulator activity [GO_0030548]

Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.

Open acetylcholine receptor regulator activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0030548",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0030548",
            "label": "acetylcholine receptor regulator activity"
        },
        "description": [
            "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0099602",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0099602",
            "label": "neurotransmitter receptor regulator activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002211",
                "label": "regulates",
                "type": "regulates"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0015464",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0015464",
                "label": "acetylcholine receptor activity"
            }
        }
    ],
    "xrefs": [],
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

147 - acetylcholine receptor signaling pathway [GO_0095500]

The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.

Open acetylcholine receptor signaling pathway in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0095500",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0095500",
            "label": "acetylcholine receptor signaling pathway"
        },
        "description": [
            "The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0098926",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0098926",
            "label": "postsynaptic signal transduction"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_1905145",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_1905145",
                "label": "cellular response to acetylcholine"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acetylcholine receptor signalling pathway",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

148 - acetylcholine secretion [GO_0061526]

The regulated release of acetylcholine by a cell.

Open acetylcholine secretion in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0061526",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0061526",
            "label": "acetylcholine secretion"
        },
        "description": [
            "The regulated release of acetylcholine by a cell."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0023061",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0023061",
            "label": "signal release"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015870",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015870",
            "label": "acetylcholine transport"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

149 - acetylcholine secretion, neurotransmission [GO_0014055]

The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).

Open acetylcholine secretion, neurotransmission in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0014055",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0014055",
            "label": "acetylcholine secretion, neurotransmission"
        },
        "description": [
            "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0007269",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0007269",
            "label": "neurotransmitter secretion"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0061526",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0061526",
            "label": "acetylcholine secretion"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0007271",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0007271",
                "label": "synaptic transmission, cholinergic"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
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                "short_form": "Unattributed",
                "label": ""
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            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
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150 - acetylcholine transport [GO_0015870]

The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.

Open acetylcholine transport in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0015870",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015870",
            "label": "acetylcholine transport"
        },
        "description": [
            "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0071705",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0071705",
            "label": "nitrogen compound transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015695",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015695",
            "label": "organic cation transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_1901374",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1901374",
            "label": "acetate ester transport"
        }
    ],
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

151 - acetylcholine-gated cation-selective channel activity [GO_0022848]

Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.

Open acetylcholine-gated cation-selective channel activity in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0022848",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0022848",
            "label": "acetylcholine-gated cation-selective channel activity"
        },
        "description": [
            "Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0099094",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0099094",
            "label": "ligand-gated cation channel activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_1904315",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1904315",
            "label": "transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0005231",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005231",
            "label": "Ca2+ influx into the post-synaptic cell"
        }
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                "label": "acetylcholine-activated cation-selective channel activity",
                "type": ""
            },
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "nicotinergic acetylcholine receptor activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acetylcholine-gated cation channel activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "nAChR",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ionotropic acetylcholine receptor activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                "symbol": "",
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

152 - acetylesterase activity [GO_0008126]

Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate.

Open acetylesterase activity in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008126",
            "symbol": "",
            "types": [
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                "Class"
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            "short_form": "GO_0008126",
            "label": "acetylesterase activity"
        },
        "description": [
            "Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0034338",
            "types": [
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            "short_form": "GO_0034338",
            "label": "short-chain carboxylesterase activity"
        }
    ],
    "relationships": [],
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        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "p-nitrophenyl acetate esterase",
                "type": ""
            },
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

153 - acetylpyruvate hydrolase activity [GO_0018773]

Catalysis of the reaction: acetylpyruvate + H2O = acetate + H+ + pyruvate.

Open acetylpyruvate hydrolase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0018773",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0018773",
            "label": "acetylpyruvate hydrolase activity"
        },
        "description": [
            "Catalysis of the reaction: acetylpyruvate + H2O = acetate + H+ + pyruvate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016823",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016823",
            "label": "hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "2,4-dioxopentanoate acetylhydrolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

154 - acetyltransferase activator activity [GO_0010698]

Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule.

Open acetyltransferase activator activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0010698",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0010698",
            "label": "acetyltransferase activator activity"
        },
        "description": [
            "Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008047",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008047",
            "label": "enzyme activator activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002213",
                "label": "positively regulates",
                "type": "positively_regulates"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0016407",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0016407",
                "label": "KAT5 acetylates ATM at DNA DSBs"
            }
        }
    ],
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

155 - acid secretion [GO_0046717]

The controlled release of acid by a cell or a tissue.

Open acid secretion in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0046717",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0046717",
            "label": "acid secretion"
        },
        "description": [
            "The controlled release of acid by a cell or a tissue."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0046903",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0046903",
            "label": "secretion"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
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                "types": [
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

156 - acid sphingomyelin phosphodiesterase activity [GO_0061750]

Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in an acidic environment.

Open acid sphingomyelin phosphodiesterase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0061750",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0061750",
            "label": "acid sphingomyelin phosphodiesterase activity"
        },
        "description": [
            "Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in an acidic environment."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004767",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004767",
            "label": "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acid SMase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

157 - acid-amino acid ligase activity [GO_0016881]

Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

Open acid-amino acid ligase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016881",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016881",
            "label": "acid-amino acid ligase activity"
        },
        "description": [
            "Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016879",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016879",
            "label": "ligase activity, forming carbon-nitrogen bonds"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "peptide synthase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

158 - acid-ammonia (or amide) ligase activity [GO_0016880]

Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

Open acid-ammonia (or amide) ligase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016880",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016880",
            "label": "acid-ammonia (or amide) ligase activity"
        },
        "description": [
            "Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016879",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016879",
            "label": "ligase activity, forming carbon-nitrogen bonds"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "amide synthase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
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            }
        }
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

159 - acid-sensing ion channel activity [GO_0044736]

Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex.

Open acid-sensing ion channel activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0044736",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0044736",
            "label": "acid-sensing ion channel activity"
        },
        "description": [
            "Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015280",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015280",
            "label": "SCNN channels transport extracellular Na+ to cytosol"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ASIC activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
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                "PubMed": "",
                "DOI": ""
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    "def_pubs": [
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

160 - acid-thiol ligase activity [GO_0016878]

Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

Open acid-thiol ligase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016878",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016878",
            "label": "acid-thiol ligase activity"
        },
        "description": [
            "Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016877",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016877",
            "label": "ligase activity, forming carbon-sulfur bonds"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

161 - acidic amino acid transmembrane transporter activity [GO_0015172]

Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3.

Open acidic amino acid transmembrane transporter activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0015172",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015172",
            "label": "acidic amino acid transmembrane transporter activity"
        },
        "description": [
            "Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015171",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015171",
            "label": "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol"
        }
    ],
    "relationships": [
        {
            "relation": {
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                "label": "is part of",
                "type": "part_of"
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            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0015800",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0015800",
                "label": "acidic amino acid transport"
            }
        }
    ],
    "xrefs": [],
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                "label": "acidic amino acid transporter activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
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                    "short_form": "Unattributed",
                    "label": ""
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                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

162 - acidic amino acid transport [GO_0015800]

The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Open acidic amino acid transport in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0015800",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015800",
            "label": "acidic amino acid transport"
        },
        "description": [
            "The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0006865",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0006865",
            "label": "amino acid transport"
        }
    ],
    "relationships": [],
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                    "pub"
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

163 - Acidification of Tf:TfR1 containing endosome [GO_0015078]

Enables the transfer of a proton from one side of a membrane to the other.

Open Acidification of Tf:TfR1 containing endosome in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0015078",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015078",
            "label": "Acidification of Tf:TfR1 containing endosome"
        },
        "description": [
            "Enables the transfer of a proton from one side of a membrane to the other."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0022890",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0022890",
            "label": "inorganic cation transmembrane transporter activity"
        }
    ],
    "relationships": [
        {
            "relation": {
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                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_1902600",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_1902600",
                "label": "proton transmembrane transport"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "hydrogen ion transmembrane transporter activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "proton transporter activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

164 - acinar cell differentiation [GO_0090425]

The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini.

Open acinar cell differentiation in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0090425",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0090425",
            "label": "acinar cell differentiation"
        },
        "description": [
            "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0002067",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0002067",
            "label": "glandular epithelial cell differentiation"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002315",
                "label": "results in acquisition of features of",
                "type": "results_in_acquisition_of_features_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/CL_0000622",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class"
                ],
                "short_form": "CL_0000622",
                "label": "acinar cell"
            }
        }
    ],
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

165 - acinar cell proliferation [GO_1990863]

The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus).

Open acinar cell proliferation in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_1990863",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1990863",
            "label": "acinar cell proliferation"
        },
        "description": [
            "The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0050673",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0050673",
            "label": "epithelial cell proliferation"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0012003",
                "label": "acts on population of",
                "type": "acts_on_population_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/CL_0000622",
                "types": [
                    "Entity",
                    "Anatomy",
                    "Class"
                ],
                "short_form": "CL_0000622",
                "label": "acinar cell"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acinic cell proliferation",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acinous cell proliferation",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
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                        "pub"
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

166 - acireductone dioxygenase [iron(II)-requiring] activity [GO_0010309]

Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 4-methylthio-2-oxobutanoate + formate + H+.

Open acireductone dioxygenase [iron(II)-requiring] activity in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0010309",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0010309",
            "label": "acireductone dioxygenase [iron(II)-requiring] activity"
        },
        "description": [
            "Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 4-methylthio-2-oxobutanoate + formate + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016702",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016702",
            "label": "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acireductone dioxygenase (Fe2+-requiring) activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ARD1",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "aci-reductone dioxygenase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "E-2'",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ARD'",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

167 - acireductone synthase activity [GO_0043874]

Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. This function is involved in the process of methionine salvage.

Open acireductone synthase activity in VFB

Term Information

  • ID: GO_0043874
  • Name: acireductone synthase activity
  • Definition: Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.
  • Synonyms:
  • Type:
  • Comment: This function is involved in the process of methionine salvage.

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0043874",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0043874",
            "unique_facets": [
                "Class"
            ],
            "label": "acireductone synthase activity"
        },
        "description": [
            "Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate."
        ],
        "comment": [
            "This function is involved in the process of methionine salvage."
        ]
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016791",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016791",
            "unique_facets": [
                "Class"
            ],
            "label": "phosphatase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "E-1 enolase-phosphatase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
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                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
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                "scope": "has_related_synonym",
                "label": "E-1",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

168 - ACP phosphopantetheine attachment site binding [GO_0044620]

Binding to the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP).

Open ACP phosphopantetheine attachment site binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0044620",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0044620",
            "label": "ACP phosphopantetheine attachment site binding"
        },
        "description": [
            "Binding to the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0051192",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0051192",
            "label": "prosthetic group binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

169 - Acrosin Cleavage [GO_0002020]

Binding to a protease or a peptidase.

Open Acrosin Cleavage in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0002020",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0002020",
            "label": "Acrosin Cleavage"
        },
        "description": [
            "Binding to a protease or a peptidase."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
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            "short_form": "GO_0019899",
            "label": "enzyme binding"
        }
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170 - ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA [GO_0031957]

Catalysis of the reaction: ATP + a very-long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22.

Open ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA in VFB

VFB Term Json

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            "short_form": "GO_0016405",
            "label": "CoA-ligase activity"
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            "short_form": "GO_0015645",
            "label": "fatty acid ligase activity"
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171 - ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell [GO_0090433]

Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA.

Open ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell in VFB

VFB Term Json

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    },
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            "iri": "http://purl.obolibrary.org/obo/GO_0004467",
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            "short_form": "GO_0004467",
            "label": "long-chain fatty acid-CoA ligase activity"
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172 - actin binding [GO_0003779]

Binding to monomeric or multimeric forms of actin, including actin filaments.

Open actin binding in VFB

VFB Term Json

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173 - actin cytoskeleton [GO_0015629]

The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.

Open actin cytoskeleton in VFB

VFB Term Json

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    ]
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174 - actin cytoskeleton organization [GO_0030036]

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.

Open actin cytoskeleton organization in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0007010",
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            "iri": "http://purl.obolibrary.org/obo/GO_0030029",
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            "short_form": "GO_0030029",
            "label": "actin filament-based process"
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175 - actin filament [GO_0005884]

A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.

Open actin filament in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0099513",
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            "label": "polymeric cytoskeletal fiber"
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176 - actin filament binding [GO_0051015]

Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.

Open actin filament binding in VFB

VFB Term Json

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        "description": [
            "Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits."
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            "iri": "http://purl.obolibrary.org/obo/GO_0003779",
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            "short_form": "GO_0003779",
            "label": "actin binding"
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            "iri": "http://purl.obolibrary.org/obo/GO_0044877",
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            "short_form": "GO_0044877",
            "label": "protein-containing complex binding"
        }
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177 - actin filament bundle [GO_0032432]

An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.

Open actin filament bundle in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0110165",
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            "short_form": "GO_0110165",
            "label": "cellular anatomical entity"
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                "label": "actin cytoskeleton"
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                "label": "actin filament"
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178 - actin filament bundle assembly [GO_0051017]

The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.

Open actin filament bundle assembly in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0022607",
            "types": [
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            "short_form": "GO_0022607",
            "label": "cellular component assembly"
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            "short_form": "GO_0061572",
            "label": "actin filament bundle organization"
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                "label": "actin filament bundle"
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        }
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    "def_pubs": []
}

179 - actin filament bundle organization [GO_0061572]

A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle.

Open actin filament bundle organization in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0061572",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
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            "short_form": "GO_0061572",
            "label": "actin filament bundle organization"
        },
        "description": [
            "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0007015",
            "types": [
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            "short_form": "GO_0007015",
            "label": "actin filament organization"
        }
    ],
    "relationships": [
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                "label": "results in organization of",
                "type": "results_in_organization_of"
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            "object": {
                "symbol": "",
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                "short_form": "GO_0032432",
                "label": "actin filament bundle"
            }
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180 - actin filament organization [GO_0007015]

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.

Open actin filament organization in VFB

VFB Term Json

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            "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking."
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            "label": "supramolecular fiber organization"
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        }
    ],
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}

181 - actin filament-based movement [GO_0030048]

Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.

Open actin filament-based movement in VFB

VFB Term Json

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                "label": ""
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182 - actin filament-based process [GO_0030029]

Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.

Open actin filament-based process in VFB

VFB Term Json

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        },
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009987",
            "types": [
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            "short_form": "GO_0009987",
            "label": "cellular process"
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                "type": ""
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183 - actin filament-based transport [GO_0099515]

The transport of organelles or other particles from one location in the cell to another along actin filaments.

Open actin filament-based transport in VFB

VFB Term Json

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            "short_form": "GO_0099515",
            "label": "actin filament-based transport"
        },
        "description": [
            "The transport of organelles or other particles from one location in the cell to another along actin filaments."
        ],
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    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0030705",
            "types": [
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            "short_form": "GO_0030705",
            "label": "cytoskeleton-dependent intracellular transport"
        }
    ],
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            },
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                "label": "actin filament"
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    ]
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184 - actin monomer binding [GO_0003785]

Binding to monomeric actin, also known as G-actin.

Open actin monomer binding in VFB

VFB Term Json

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            "label": "actin monomer binding"
        },
        "description": [
            "Binding to monomeric actin, also known as G-actin."
        ],
        "comment": []
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    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0003779",
            "types": [
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            "short_form": "GO_0003779",
            "label": "actin binding"
        }
    ],
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                "label": ""
            },
            "FlyBase": "",
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            "DOI": ""
        }
    ]
}

185 - actin-based cell projection [GO_0098858]

A cell projection supported by an assembly of actin filaments, and which lacks microtubules.

Open actin-based cell projection in VFB

VFB Term Json

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            "label": "actin-based cell projection"
        },
        "description": [
            "A cell projection supported by an assembly of actin filaments, and which lacks microtubules."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0120025",
            "types": [
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            "short_form": "GO_0120025",
            "label": "plasma membrane bounded cell projection"
        }
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    "relationships": [
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                "type": "has_part"
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                "label": "actin filament"
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                "label": ""
            },
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            "DOI": ""
        }
    ]
}

186 - actinin binding [GO_0042805]

Binding to actinin, any member of a family of proteins that crosslink F-actin.

Open actinin binding in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0042805",
            "symbol": "",
            "types": [
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            "short_form": "GO_0042805",
            "label": "actinin binding"
        },
        "description": [
            "Binding to actinin, any member of a family of proteins that crosslink F-actin."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008092",
            "types": [
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            "short_form": "GO_0008092",
            "label": "cytoskeletal protein binding"
        }
    ],
    "relationships": [],
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                "type": ""
            },
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        }
    ],
    "def_pubs": []
}

187 - action potential [GO_0001508]

A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities. Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so.

Open action potential in VFB

VFB Term Json

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            "short_form": "GO_0001508",
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        "description": [
            "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities."
        ],
        "comment": [
            "Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0042391",
            "types": [
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            "short_form": "GO_0042391",
            "label": "regulation of membrane potential"
        }
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    ]
}

188 - Activated Adenylyl cyclase synthesizes cyclic AMP [GO_0004016]

Catalysis of the reaction: ATP = 3’,5’-cyclic AMP + diphosphate.

Open Activated Adenylyl cyclase synthesizes cyclic AMP in VFB

VFB Term Json

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            "short_form": "GO_0004016",
            "label": "Activated Adenylyl cyclase synthesizes cyclic AMP"
        },
        "description": [
            "Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009975",
            "types": [
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            "short_form": "GO_0009975",
            "label": "cyclase activity"
        },
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016849",
            "types": [
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                "Class"
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            "short_form": "GO_0016849",
            "label": "phosphorus-oxygen lyase activity"
        }
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189 - Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. [GO_0004707]

Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.

Open Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. in VFB

VFB Term Json

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            "short_form": "GO_0004707",
            "label": "Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2."
        },
        "description": [
            "Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004674",
            "types": [
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            "short_form": "GO_0004674",
            "label": "Activation of NLK"
        }
    ],
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                "short_form": "GO_0000165",
                "label": "MAPK cascade"
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        }
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                "FlyBase": "",
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            }
        },
        {
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                "label": "mitogen activated kinase activity",
                "type": ""
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        },
        {
            "synonym": {
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                "DOI": ""
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        },
        {
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                "label": "ERK1",
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            "pub": {
                "core": {
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                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
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        },
        {
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                "label": "ERK2",
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                    "label": ""
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                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
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        },
        {
            "synonym": {
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                "label": "MAP kinase 2 activity",
                "type": ""
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                    "label": ""
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                "DOI": ""
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        },
        {
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                "type": ""
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            "pub": {
                "core": {
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                    "label": ""
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                "FlyBase": "",
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        },
        {
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                "scope": "has_narrow_synonym",
                "label": "SAP kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "stress-activated kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
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                    "iri": "http://flybase.org/reports/Unattributed",
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                    "label": ""
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                "DOI": ""
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        },
        {
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                "label": "MBP kinase I activity",
                "type": ""
            },
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    "def_pubs": []
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190 - Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 [GO_0004708]

Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.

Open Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 in VFB

VFB Term Json

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            "short_form": "GO_0004708",
            "label": "Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3"
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        "description": [
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        ],
        "comment": []
    },
    "query": "Get JSON for Class",
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004712",
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            "short_form": "GO_0004712",
            "label": "Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants"
        }
    ],
    "relationships": [
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                "iri": "http://purl.obolibrary.org/obo/GO_0000165",
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                "short_form": "GO_0000165",
                "label": "MAPK cascade"
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                "DOI": ""
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        },
        {
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            "pub": {
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        {
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        },
        {
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191 - Activated JNK phosphorylates c-JUN [GO_0004705]

Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors.

Open Activated JNK phosphorylates c-JUN in VFB

VFB Term Json

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            "short_form": "GO_0004705",
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        "description": [
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            "iri": "http://purl.obolibrary.org/obo/GO_0004707",
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            "short_form": "GO_0004707",
            "label": "Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2."
        }
    ],
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                "iri": "http://purl.obolibrary.org/obo/GO_0007254",
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                "short_form": "GO_0007254",
                "label": "JNK cascade"
            }
        }
    ],
    "xrefs": [],
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        },
        {
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        },
        {
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        }
    ],
    "def_pubs": []
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192 - Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants [GO_0004712]

Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.

Open Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants in VFB

VFB Term Json

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        "description": [
            "Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
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    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004672",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0004672",
            "label": "IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation"
        }
    ],
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        },
        {
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    ],
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193 - Activated type I receptor phosphorylates R-Smad1/5/8 directly [GO_0004675]

Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

Open Activated type I receptor phosphorylates R-Smad1/5/8 directly in VFB

VFB Term Json

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            "short_form": "GO_0004675",
            "label": "Activated type I receptor phosphorylates R-Smad1/5/8 directly"
        },
        "description": [
            "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019199",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0019199",
            "label": "JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004674",
            "types": [
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            "short_form": "GO_0004674",
            "label": "Activation of NLK"
        }
    ],
    "relationships": [
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                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0007178",
                "types": [
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                "short_form": "GO_0007178",
                "label": "transmembrane receptor protein serine/threonine kinase signaling pathway"
            }
        }
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                "type": ""
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194 - activation of cysteine-type endopeptidase activity involved in apoptotic process [GO_0006919]

Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process. This term should be used when the annotation refers to a process that occurs in a context of apoptotic cell death. To annotate gene products involved in activation of cysteine-type endopeptidases in other cellular process (e.g., cell cycle arrest) that do not necessarily develop into an apoptotic process, please use the more general parent term GO:0097202. Examples of ‘activation of cysteine-type endopeptidase activity involved in apoptotic process’ are cytochrome c and Apaf1. When cytochrome c is released from mitochondria and forms a complex with Apaf1, they form a scaffolding platform in which the pro-caspase 9 is bound (the ‘apoptosome’). The caspase is then cleaved and activated. Cytochrome c and Apaf1 are therefore involved in the conversion of the zymogen procaspase 9 to the active form of the caspase.

Open activation of cysteine-type endopeptidase activity involved in apoptotic process in VFB

VFB Term Json

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            "short_form": "GO_0006919",
            "label": "activation of cysteine-type endopeptidase activity involved in apoptotic process"
        },
        "description": [
            "Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process."
        ],
        "comment": [
            "This term should be used when the annotation refers to a process that occurs in a context of apoptotic cell death. To annotate gene products involved in activation of cysteine-type endopeptidases in other cellular process (e.g., cell cycle arrest) that do not necessarily develop into an apoptotic process, please use the more general parent term GO:0097202. Examples of 'activation of cysteine-type endopeptidase activity involved in apoptotic process' are cytochrome c and Apaf1. When cytochrome c is released from mitochondria and forms a complex with Apaf1, they form a scaffolding platform in which the pro-caspase 9 is bound (the 'apoptosome'). The caspase is then cleaved and activated. Cytochrome c and Apaf1 are therefore involved in the conversion of the zymogen procaspase 9 to the active form of the caspase."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
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            "iri": "http://purl.obolibrary.org/obo/GO_0043280",
            "types": [
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            "short_form": "GO_0043280",
            "label": "positive regulation of cysteine-type endopeptidase activity involved in apoptotic process"
        }
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    ],
    "def_pubs": []
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195 - Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors [GO_0015276]

Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

Open Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors in VFB

VFB Term Json

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                "Class"
            ],
            "short_form": "GO_0015276",
            "label": "Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors"
        },
        "description": [
            "Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0005216",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0005216",
            "label": "ion channel activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0022834",
            "types": [
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                "Class"
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            "short_form": "GO_0022834",
            "label": "ligand-gated channel activity"
        }
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            }
        }
    ],
    "def_pubs": []
}

196 - Activation of NLK [GO_0004674]

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

Open Activation of NLK in VFB

VFB Term Json

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            "types": [
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                "Class"
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            "short_form": "GO_0004674",
            "label": "Activation of NLK"
        },
        "description": [
            "Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004672",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004672",
            "label": "IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "protein threonine kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "serine-specific protein kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

197 - Activation of TWIK-related K+ channel (TREK) [GO_0005267]

Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.

Open Activation of TWIK-related K+ channel (TREK) in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0005267",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005267",
            "label": "Activation of TWIK-related K+ channel (TREK)"
        },
        "description": [
            "Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015079",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015079",
            "label": "potassium ion transmembrane transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0005261",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005261",
            "label": "STIM1 oligomerizes"
        }
    ],
    "relationships": [],
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    "pub_syn": [],
    "def_pubs": [
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                "types": [
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

198 - active ion transmembrane transporter activity [GO_0022853]

Enables the transfer of an ion from one side of a membrane to the other up the solute’s concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.

Open active ion transmembrane transporter activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0022853",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0022853",
            "label": "active ion transmembrane transporter activity"
        },
        "description": [
            "Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0022804",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0022804",
            "label": "active transmembrane transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015075",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015075",
            "label": "ion transmembrane transporter activity"
        }
    ],
    "relationships": [],
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                "types": [
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

199 - Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308 [GO_0010857]

Calcium-dependent catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the presence of calcium.

Open Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308 in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0010857",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0010857",
            "label": "Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308"
        },
        "description": [
            "Calcium-dependent catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP."
        ],
        "comment": [
            "This reaction requires the presence of calcium."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004672",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004672",
            "label": "IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation"
        }
    ],
    "relationships": [],
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    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

200 - Active PLCG1 hydrolyses PIP2 [GO_0004435]

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H+.

Open Active PLCG1 hydrolyses PIP2 in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004435",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004435",
            "label": "Active PLCG1 hydrolyses PIP2"
        },
        "description": [
            "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004629",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004629",
            "label": "PLC gamma 2-mediated PIP2 hydrolysis"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "phosphatidylinositol-4,5-bisphosphate hydrolysis",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity",
                "type": ""
            },
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
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                "scope": "has_related_synonym",
                "label": "PI-PLC activity",
                "type": ""
            },
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

201 - active transmembrane transporter activity [GO_0022804]

Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute’s concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.

Open active transmembrane transporter activity in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0022804",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0022804",
            "label": "active transmembrane transporter activity"
        },
        "description": [
            "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0022857",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0022857",
            "label": "An unknown carrier transports mitochondrial glyoxylate to the cytosol"
        }
    ],
    "relationships": [],
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    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "pump activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "active carrier activity",
                "type": ""
            },
            "pub": {
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                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "permease activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "carrier activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

202 - activin binding [GO_0048185]

Binding to activin, a dimer of inhibin-beta subunits.

Open activin binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0048185",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0048185",
            "label": "activin binding"
        },
        "description": [
            "Binding to activin, a dimer of inhibin-beta subunits."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0044877",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0044877",
            "label": "protein-containing complex binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

203 - activin receptor activity [GO_0017002]

Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta. Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand activin. For binding to other extracellular ligands, consider annotating to terms under ’transmembrane signaling receptor activity ; GO:0004888.

Open activin receptor activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0017002",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0017002",
            "label": "activin receptor activity"
        },
        "description": [
            "Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta."
        ],
        "comment": [
            "Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand activin. For binding to other extracellular ligands, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004675",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004675",
            "label": "Activated type I receptor phosphorylates R-Smad1/5/8 directly"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0032924",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0032924",
                "label": "activin receptor signaling pathway"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000051",
                "label": "has part",
                "type": "has_part"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0048185",
                "types": [
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                    "Class"
                ],
                "short_form": "GO_0048185",
                "label": "activin binding"
            }
        }
    ],
    "xrefs": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "activin-activated receptor activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
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                "PubMed": "",
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    ],
    "def_pubs": [
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

204 - activin receptor activity, type I [GO_0016361]

Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals.

Open activin receptor activity, type I in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016361",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016361",
            "label": "activin receptor activity, type I"
        },
        "description": [
            "Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0017002",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0017002",
            "label": "activin receptor activity"
        }
    ],
    "relationships": [],
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    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "type I activin receptor activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

205 - activin receptor activity, type II [GO_0016362]

Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.

Open activin receptor activity, type II in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016362",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016362",
            "label": "activin receptor activity, type II"
        },
        "description": [
            "Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0017002",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0017002",
            "label": "activin receptor activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "type II activin receptor activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
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            }
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

206 - activin receptor binding [GO_0070697]

Binding to an activin receptor.

Open activin receptor binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0070697",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0070697",
            "label": "activin receptor binding"
        },
        "description": [
            "Binding to an activin receptor."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0070696",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0070696",
            "label": "transmembrane receptor protein serine/threonine kinase binding"
        }
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207 - activin receptor signaling pathway [GO_0032924]

The series of molecular signals initiated by an extracellular ligand binding to an activin receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

Open activin receptor signaling pathway in VFB

VFB Term Json

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            "short_form": "GO_0032924",
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            "iri": "http://purl.obolibrary.org/obo/GO_0007178",
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            "short_form": "GO_0007178",
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208 - actomyosin [GO_0042641]

Any complex of actin, myosin, and accessory proteins.

Open actomyosin in VFB

VFB Term Json

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            "short_form": "GO_0110165",
            "label": "cellular anatomical entity"
        }
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                "iri": "http://purl.obolibrary.org/obo/GO_0015629",
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                "short_form": "GO_0015629",
                "label": "actin cytoskeleton"
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209 - actomyosin structure organization [GO_0031032]

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. Note that this term is a child of ‘actin cytoskeleton organization and biogenesis ; GO:0030036’ because the actin cytoskeleton is defined as actin filaments and associated proteins.

Open actomyosin structure organization in VFB

VFB Term Json

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            "short_form": "GO_0031032",
            "label": "actomyosin structure organization"
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            "Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins."
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    "parents": [
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0030036",
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            "label": "actin cytoskeleton organization"
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    "relationships": [
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                "label": "results in organization of",
                "type": "results_in_organization_of"
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            "object": {
                "symbol": "",
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        }
    ],
    "def_pubs": []
}

210 - acyl binding [GO_0000035]

Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.

Open acyl binding in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0005488",
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            "short_form": "GO_0005488",
            "label": "binding"
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                "type": "has_input"
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                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/CHEBI_22221",
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                "short_form": "CHEBI_22221",
                "label": "acyl group"
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    ]
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211 - acyl carnitine transmembrane transport [GO_1902616]

The process in which acyl carnitine is transported across a membrane.

Open acyl carnitine transmembrane transport in VFB

VFB Term Json

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            "short_form": "GO_1902616",
            "label": "acyl carnitine transmembrane transport"
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        "description": [
            "The process in which acyl carnitine is transported across a membrane."
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0055085",
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            "short_form": "GO_0055085",
            "label": "transmembrane transport"
        },
        {
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            "iri": "http://purl.obolibrary.org/obo/GO_0006844",
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            "short_form": "GO_0006844",
            "label": "acyl carnitine transport"
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    ]
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212 - acyl carnitine transmembrane transporter activity [GO_0015227]

Enables the transfer of acyl carnitine from one side of a membrane to the other. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.

Open acyl carnitine transmembrane transporter activity in VFB

VFB Term Json

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            "short_form": "GO_0015227",
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        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015651",
            "types": [
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            "short_form": "GO_0015651",
            "label": "quaternary ammonium group transmembrane transporter activity"
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                "label": "acyl carnitine transmembrane transport"
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213 - acyl carnitine transport [GO_0006844]

The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.

Open acyl carnitine transport in VFB

VFB Term Json

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            "short_form": "GO_0006844",
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        "description": [
            "The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane."
        ],
        "comment": []
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    "query": "Get JSON for Class",
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            "short_form": "GO_0015697",
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214 - acyl carrier activity [GO_0000036]

Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis.

Open acyl carrier activity in VFB

VFB Term Json

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            "symbol": "",
            "types": [
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            "short_form": "GO_0000036",
            "label": "acyl carrier activity"
        },
        "description": [
            "Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0044620",
            "types": [
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                "Class"
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            "short_form": "GO_0044620",
            "label": "ACP phosphopantetheine attachment site binding"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140414",
            "types": [
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            "short_form": "GO_0140414",
            "label": "phosphopantetheine-dependent carrier activity"
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                "iri": "http://purl.obolibrary.org/obo/GO_0006633",
                "types": [
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                "short_form": "GO_0006633",
                "label": "fatty acid biosynthetic process"
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        }
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    ]
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215 - acyl-CoA binding [GO_0120227]

Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid.

Open acyl-CoA binding in VFB

VFB Term Json

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            "short_form": "GO_0120227",
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        "description": [
            "Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid."
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        "comment": []
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    "query": "Get JSON for Class",
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            "iri": "http://purl.obolibrary.org/obo/GO_1901681",
            "types": [
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            "short_form": "GO_1901681",
            "label": "sulfur compound binding"
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            "iri": "http://purl.obolibrary.org/obo/GO_0032559",
            "types": [
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            "short_form": "GO_0032559",
            "label": "adenyl ribonucleotide binding"
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            "short_form": "GO_0033218",
            "label": "amide binding"
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            "pub": {
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
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    "def_pubs": [
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                "types": [
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                    "pub"
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

216 - acyl-CoA desaturase activity [GO_0016215]

Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O.

Open acyl-CoA desaturase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016215",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016215",
            "label": "acyl-CoA desaturase activity"
        },
        "description": [
            "Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016717",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016717",
            "label": "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "CoA desaturase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
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                "DOI": ""
            }
        }
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    "def_pubs": [
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

217 - acyl-CoA hydrolase activity [GO_0047617]

Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate.

Open acyl-CoA hydrolase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0047617",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0047617",
            "label": "acyl-CoA hydrolase activity"
        },
        "description": [
            "Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016289",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016289",
            "label": "CoA hydrolase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acyl-CoA thiolesterase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "acyl-CoA thioesterase I activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acyl-CoA thioesterase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "acyl-CoA thioesterase II activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

218 - acyl-CoA N-acyltransferase activity [GO_0019186]

Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule.

Open acyl-CoA N-acyltransferase activity in VFB

Term Information

  • ID: GO_0019186
  • Name: acyl-CoA N-acyltransferase activity
  • Definition: Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0019186",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0019186",
            "unique_facets": [
                "Class"
            ],
            "label": "acyl-CoA N-acyltransferase activity"
        },
        "description": [
            "Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016410",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016410",
            "unique_facets": [
                "Class"
            ],
            "label": "N-acyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
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                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

219 - acylglycerol biosynthetic process [GO_0046463]

The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.

Open acylglycerol biosynthetic process in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0046463",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0046463",
            "label": "acylglycerol biosynthetic process"
        },
        "description": [
            "The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0046460",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0046460",
            "label": "neutral lipid biosynthetic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0045017",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0045017",
            "label": "glycerolipid biosynthetic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0006639",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0006639",
            "label": "acylglycerol metabolic process"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acylglycerol synthesis",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acylglycerol formation",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acylglycerol anabolism",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acylglycerol biosynthesis",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
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                "symbol": "",
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

220 - acylglycerol kinase activity [GO_0047620]

Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate.

Open acylglycerol kinase activity in VFB

Term Information

  • ID: GO_0047620
  • Name: acylglycerol kinase activity
  • Definition: Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0047620",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0047620",
            "unique_facets": [
                "Class"
            ],
            "label": "acylglycerol kinase activity"
        },
        "description": [
            "Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016301",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016301",
            "unique_facets": [
                "Class"
            ],
            "label": "FN3KRP phosphorylates PsiAm, RibAm"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016773",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016773",
            "unique_facets": [
                "Class"
            ],
            "label": "phosphotransferase activity, alcohol group as acceptor"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "monoacylglycerol kinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

221 - acylglycerol metabolic process [GO_0006639]

The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.

Open acylglycerol metabolic process in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0006639",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0006639",
            "label": "acylglycerol metabolic process"
        },
        "description": [
            "The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0046486",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0046486",
            "label": "glycerolipid metabolic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0006638",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0006638",
            "label": "neutral lipid metabolic process"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acylglycerol metabolism",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "glyceride metabolic process",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "glyceride metabolism",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

222 - acylphosphatase activity [GO_0003998]

Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.

Open acylphosphatase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003998",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003998",
            "label": "acylphosphatase activity"
        },
        "description": [
            "Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016462",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016462",
            "label": "pyrophosphatase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acetic phosphatase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

223 - acyltransferase activity, acyl groups converted into alkyl on transfer [GO_0046912]

Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer.

Open acyltransferase activity, acyl groups converted into alkyl on transfer in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0046912",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0046912",
            "label": "acyltransferase activity, acyl groups converted into alkyl on transfer"
        },
        "description": [
            "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016746",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016746",
            "label": "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "acyltransferase, acyl groups converted into alkyl on transfer",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
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                "symbol": "",
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                "types": [
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

224 - acyltransferase activity, transferring groups other than amino-acyl groups [GO_0016747]

Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).

Open acyltransferase activity, transferring groups other than amino-acyl groups in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016747",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016747",
            "label": "acyltransferase activity, transferring groups other than amino-acyl groups"
        },
        "description": [
            "Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016746",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016746",
            "label": "Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "transferase activity, transferring acyl groups other than amino-acyl groups",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "transferase activity, transferring groups other than amino-acyl groups",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

225 - ADAM10:Zn2+:TSPANs cleaves APP(18-770) [GO_1902945]

Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process.

Open ADAM10:Zn2+:TSPANs cleaves APP(18-770) in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_1902945",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1902945",
            "label": "ADAM10:Zn2+:TSPANs cleaves APP(18-770)"
        },
        "description": [
            "Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004222",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004222",
            "label": "OMA1 hydrolyses OPA1"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0042987",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0042987",
                "label": "amyloid precursor protein catabolic process"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "metalloendoproteinase activity involved in amyloid precursor protein degradation",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

226 - ADAT1 deaminates adenosine-37 in tRNA(Ala) [GO_0008251]

Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule.

Open ADAT1 deaminates adenosine-37 in tRNA(Ala) in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008251",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008251",
            "label": "ADAT1 deaminates adenosine-37 in tRNA(Ala)"
        },
        "description": [
            "Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004000",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004000",
            "label": "abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "tRNA-adenosine deaminase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

227 - Addition of a third mannose to the N-glycan precursor by ALG2 [GO_0000009]

Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.

Open Addition of a third mannose to the N-glycan precursor by ALG2 in VFB

Term Information

  • ID: GO_0000009
  • Name: Addition of a third mannose to the N-glycan precursor by ALG2
  • Definition: Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0000009",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0000009",
            "unique_facets": [
                "Class"
            ],
            "label": "Addition of a third mannose to the N-glycan precursor by ALG2"
        },
        "description": [
            "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0000030",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0000030",
            "unique_facets": [
                "Class"
            ],
            "label": "mannosyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1,6-alpha-mannosyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

228 - Addition of GlcNAc to the glycan on the A arm [GO_0003827]

Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H+ + UDP.

Open Addition of GlcNAc to the glycan on the A arm in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003827",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003827",
            "label": "Addition of GlcNAc to the glycan on the A arm"
        },
        "description": [
            "Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H+ + UDP."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140103",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140103",
            "label": "catalytic activity, acting on a glycoprotein"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008375",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008375",
            "label": "POMGNT2 transfers GlcNAc to Man-DAG1"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "uridine diphosphoacetylglucosamine-alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

229 - Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein [GO_0008499]

Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP.

Open Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008499",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008499",
            "label": "Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein"
        },
        "description": [
            "Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0048531",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0048531",
            "label": "beta-1,3-galactosyltransferase activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0035250",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0035250",
            "label": "UDP-galactosyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "beta-1,3-GalTase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "beta3Gal-Ts activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

230 - Addition of isopentenyl pyrophosphate to DMAPP [GO_0004161]

Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate. Note that this is the first step in the formation of farnesyl diphosphate. The second step is ‘geranyltranstransferase activity ; GO:0004337’. Consider also annotating to the biological process term ‘farnesyl diphosphate biosynthetic process ; GO:0045337’.

Open Addition of isopentenyl pyrophosphate to DMAPP in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004161",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004161",
            "label": "Addition of isopentenyl pyrophosphate to DMAPP"
        },
        "description": [
            "Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate."
        ],
        "comment": [
            "Note that this is the first step in the formation of farnesyl diphosphate. The second step is 'geranyltranstransferase activity ; GO:0004337'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004659",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004659",
            "label": "prenyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "geranyl diphosphate synthase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dimethylallyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "trans-farnesyl pyrophosphate synthetase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

231 - Addition of N-acetyl-D-glucosamine to Dolichyl phosphate [GO_0003975]

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.

Open Addition of N-acetyl-D-glucosamine to Dolichyl phosphate in VFB

Term Information

  • ID: GO_0003975
  • Name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate
  • Definition: Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003975",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003975",
            "unique_facets": [
                "Class"
            ],
            "label": "Addition of N-acetyl-D-glucosamine to Dolichyl phosphate"
        },
        "description": [
            "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016780",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016780",
            "unique_facets": [
                "Class"
            ],
            "label": "phosphotransferase activity, for other substituted phosphate groups"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

232 - adenine binding [GO_0002055]

Binding to adenine, a purine base.

Open adenine binding in VFB

Term Information

  • ID: GO_0002055
  • Name: adenine binding
  • Definition: Binding to adenine, a purine base.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0002055",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0002055",
            "unique_facets": [
                "Class"
            ],
            "label": "adenine binding"
        },
        "description": [
            "Binding to adenine, a purine base."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0002060",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0002060",
            "unique_facets": [
                "Class"
            ],
            "label": "purine nucleobase binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "6-aminopurine binding",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

233 - adenine nucleotide transmembrane transporter activity [GO_0000295]

Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.

Open adenine nucleotide transmembrane transporter activity in VFB

VFB Term Json

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    "term": {
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            "symbol": "",
            "types": [
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                "Class"
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            "short_form": "GO_0000295",
            "label": "adenine nucleotide transmembrane transporter activity"
        },
        "description": [
            "Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015216",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015216",
            "label": "purine nucleotide transmembrane transporter activity"
        }
    ],
    "relationships": [
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                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0051503",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0051503",
                "label": "adenine nucleotide transport"
            }
        }
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                    "pub"
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

234 - adenine nucleotide transport [GO_0051503]

The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Open adenine nucleotide transport in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0051503",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0051503",
            "label": "adenine nucleotide transport"
        },
        "description": [
            "The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015865",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015865",
            "label": "purine nucleotide transport"
        }
    ],
    "relationships": [],
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                "iri": "http://flybase.org/reports/Unattributed",
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

235 - adenosine 3',5'-bisphosphate transmembrane transport [GO_0071106]

The process in which adenosine 3’,5’-bisphosphate is transported across a membrane. Note that this term is not intended for use in annotating lateral movement within membranes.

Open adenosine 3’,5’-bisphosphate transmembrane transport in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0071106",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0071106",
            "label": "adenosine 3',5'-bisphosphate transmembrane transport"
        },
        "description": [
            "The process in which adenosine 3',5'-bisphosphate is transported across a membrane."
        ],
        "comment": [
            "Note that this term is not intended for use in annotating lateral movement within membranes."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_1901679",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1901679",
            "label": "nucleotide transmembrane transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015868",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015868",
            "label": "purine ribonucleotide transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0051503",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0051503",
            "label": "adenine nucleotide transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0072530",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0072530",
            "label": "purine-containing compound transmembrane transport"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adenosine 3',5'-bisphosphate membrane transport",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

236 - adenosine 3',5'-bisphosphate transmembrane transporter activity [GO_0071077]

Enables the transfer of adenosine 3’,5’-bisphosphate from one side of a membrane to the other.

Open adenosine 3’,5’-bisphosphate transmembrane transporter activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0071077",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0071077",
            "label": "adenosine 3',5'-bisphosphate transmembrane transporter activity"
        },
        "description": [
            "Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0000295",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0000295",
            "label": "adenine nucleotide transmembrane transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0005346",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005346",
            "label": "purine ribonucleotide transmembrane transporter activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0071106",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0071106",
                "label": "adenosine 3',5'-bisphosphate transmembrane transport"
            }
        }
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

237 - adenosine 5'-monophosphoramidase activity [GO_0043530]

Catalysis of the reaction: adenosine 5’-monophosphoramidate + H2O = AMP + NH4+. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester.

Open adenosine 5’-monophosphoramidase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0043530",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0043530",
            "label": "adenosine 5'-monophosphoramidase activity"
        },
        "description": [
            "Catalysis of the reaction: adenosine 5'-monophosphoramidate + H2O = AMP + NH4+. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016811",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016811",
            "label": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adenosine 5'-monophosphoramidate hydrolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adenosine 5' monophosphoramidase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

238 - adenosine-phosphate deaminase activity [GO_0047623]

Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP. Consider instead annotating to one of the more specific terms: AMP deaminase activity ; GO:0003876, ADP deaminase activity ; GO:0047629, or ATP deaminase activity ; GO:0047692.

Open adenosine-phosphate deaminase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0047623",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0047623",
            "label": "adenosine-phosphate deaminase activity"
        },
        "description": [
            "Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP."
        ],
        "comment": [
            "Consider instead annotating to one of the more specific terms: AMP deaminase activity ; GO:0003876, ADP deaminase activity ; GO:0047629, or ATP deaminase activity ; GO:0047692."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016814",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016814",
            "label": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019239",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0019239",
            "label": "HRSP12 deaminates 2AA to 2OBUTA"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "adenosine (phosphate) deaminase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

239 - adenosylhomocysteinase activity [GO_0004013]

Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.

Open adenosylhomocysteinase activity in VFB

Term Information

  • ID: GO_0004013
  • Name: adenosylhomocysteinase activity
  • Definition: Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004013",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004013",
            "unique_facets": [
                "Class"
            ],
            "label": "adenosylhomocysteinase activity"
        },
        "description": [
            "Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0046508",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0046508",
            "unique_facets": [
                "Class"
            ],
            "label": "hydrolase activity, acting on carbon-sulfur bonds"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "S-adenosyl-L-homocysteine hydrolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "S-adenosylhomocysteinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "SAHase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "S-adenosylhomocysteine synthase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "adenosylhomocysteine hydrolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "S-adenosylhomocysteine hydrolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "AdoHcyase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

240 - adenosylmethionine decarboxylase activity [GO_0004014]

Catalysis of the reaction: S-adenosyl-L-methionine + H+ = S-adenosylmethioninamine + CO2.

Open adenosylmethionine decarboxylase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004014",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004014",
            "label": "adenosylmethionine decarboxylase activity"
        },
        "description": [
            "Catalysis of the reaction: S-adenosyl-L-methionine + H+ = S-adenosylmethioninamine + CO2."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016831",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016831",
            "label": "PXLP-K333-GADL1 decarboxylates CSA to HTAU"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adenosyl methionine decarboxylase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "S-adenosyl-L-methionine carboxy-lyase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

241 - adenyl nucleotide binding [GO_0030554]

Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate.

Open adenyl nucleotide binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0030554",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0030554",
            "label": "adenyl nucleotide binding"
        },
        "description": [
            "Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0017076",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0017076",
            "label": "purine nucleotide binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

242 - adenyl ribonucleotide binding [GO_0032559]

Binding to an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.

Open adenyl ribonucleotide binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0032559",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
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            "short_form": "GO_0032559",
            "label": "adenyl ribonucleotide binding"
        },
        "description": [
            "Binding to an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety."
        ],
        "comment": []
    },
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0032555",
            "types": [
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            "short_form": "GO_0032555",
            "label": "purine ribonucleotide binding"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0030554",
            "types": [
                "Entity",
                "Class"
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            "short_form": "GO_0030554",
            "label": "adenyl nucleotide binding"
        }
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243 - adenylate cyclase activator activity [GO_0010856]

Binds to and increases the activity of adenylate cyclase.

Open adenylate cyclase activator activity in VFB

VFB Term Json

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            "Binds to and increases the activity of adenylate cyclase."
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            "short_form": "GO_0010853",
            "label": "cyclase activator activity"
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0010854",
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            "short_form": "GO_0010854",
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            "DOI": ""
        }
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244 - adenylate cyclase binding [GO_0008179]

Binding to an adenylate cyclase.

Open adenylate cyclase binding in VFB

VFB Term Json

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            "Binding to an adenylate cyclase."
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0019899",
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            "short_form": "GO_0019899",
            "label": "enzyme binding"
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    ]
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245 - adenylate cyclase inhibiting G protein-coupled glutamate receptor activity [GO_0001640]

Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.

Open adenylate cyclase inhibiting G protein-coupled glutamate receptor activity in VFB

VFB Term Json

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246 - adenylate cyclase inhibitor activity [GO_0010855]

Binds to and decreases the activity adenylate cyclase.

Open adenylate cyclase inhibitor activity in VFB

VFB Term Json

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            "Binds to and decreases the activity adenylate cyclase."
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            "iri": "http://purl.obolibrary.org/obo/GO_0010852",
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}

247 - adenylate cyclase regulator activity [GO_0010854]

Binds to and modulates the activity of adenylate cyclase.

Open adenylate cyclase regulator activity in VFB

VFB Term Json

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    "term": {
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            "iri": "http://purl.obolibrary.org/obo/GO_0010854",
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        "description": [
            "Binds to and modulates the activity of adenylate cyclase."
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    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0010851",
            "types": [
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            "short_form": "GO_0010851",
            "label": "cyclase regulator activity"
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                "type": "regulates"
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                "types": [
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
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            "DOI": ""
        }
    ]
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248 - adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO_0007189]

A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling. This term can be used to annotate ligands, receptors and G-proteins that lead to activation of adenylate cyclase activity within a signaling pathway.

Open adenylate cyclase-activating G protein-coupled receptor signaling pathway in VFB

Term Information

  • ID: GO_0007189
  • Name: adenylate cyclase-activating G protein-coupled receptor signaling pathway
  • Definition: A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling.
  • Synonyms:
  • Type:
  • Comment: This term can be used to annotate ligands, receptors and G-proteins that lead to activation of adenylate cyclase activity within a signaling pathway.

VFB Term Json

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        },
        "description": [
            "A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling."
        ],
        "comment": [
            "This term can be used to annotate ligands, receptors and G-proteins that lead to activation of adenylate cyclase activity within a signaling pathway."
        ]
    },
    "query": "Get JSON for Class",
    "version": "08f7a30",
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0007188",
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            "short_form": "GO_0007188",
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            "label": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway"
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    ],
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                "label": "ADCY3:GNAL:GTP converts ATP to cAMP"
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        },
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        {
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    ],
    "def_pubs": []
}

249 - adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO_0007196]

An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor, and ending with the regulation of a downstream cellular process.

Open adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway in VFB

VFB Term Json

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            "label": "adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway"
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        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0007193",
            "types": [
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            "short_form": "GO_0007193",
            "label": "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway"
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            "iri": "http://purl.obolibrary.org/obo/GO_0007216",
            "types": [
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                "Class"
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            "short_form": "GO_0007216",
            "label": "G protein-coupled glutamate receptor signaling pathway"
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250 - adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO_0007193]

A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP). This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase inhibition.

Open adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway in VFB

VFB Term Json

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                "label": "negative regulation of cAMP-mediated signaling"
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251 - adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO_0007188]

A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of adenylyl cyclase activity and a subsequent change in the intracellular concentration of cyclic AMP (cAMP). This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase activity. For steps upstream of adenylate cyclase activity, consider instead annotating to ‘regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway ; GO:0010578.

Open adenylate cyclase-modulating G protein-coupled receptor signaling pathway in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0007186",
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            "short_form": "GO_0007186",
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                "label": "regulation of adenylate cyclase activity"
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                "label": "regulation of cAMP-mediated signaling"
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252 - adenylosuccinate synthase activity [GO_0004019]

Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H+ + phosphate.

Open adenylosuccinate synthase activity in VFB

VFB Term Json

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            "Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H+ + phosphate."
        ],
        "comment": []
    },
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            "short_form": "GO_0016879",
            "label": "ligase activity, forming carbon-nitrogen bonds"
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    ],
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253 - adenylyltransferase activity [GO_0070566]

Catalysis of the transfer of an adenylyl group to an acceptor.

Open adenylyltransferase activity in VFB

VFB Term Json

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            "short_form": "GO_0070566",
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            "Catalysis of the transfer of an adenylyl group to an acceptor."
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    "query": "Get JSON for Class",
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            "short_form": "GO_0016779",
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254 - ADH5 oxidises S-HMGSH to S-FGSH [GO_0051903]

Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.

Open ADH5 oxidises S-HMGSH to S-FGSH in VFB

VFB Term Json

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            "label": "RDH11 reduces RBP2:atRAL to RBP2:atROL"
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255 - adipokinetic hormone binding [GO_0097004]

Binding to an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.

Open adipokinetic hormone binding in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0017046",
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256 - adipokinetic hormone receptor activity [GO_0097003]

Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.

Open adipokinetic hormone receptor activity in VFB

VFB Term Json

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    },
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                "label": "AKH receptor activity",
                "type": ""
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257 - adipokinetic hormone receptor binding [GO_0097005]

Binding to an adipokinetic hormone receptor. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.

Open adipokinetic hormone receptor binding in VFB

VFB Term Json

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        ],
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    },
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0051428",
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            "short_form": "GO_0051428",
            "label": "peptide hormone receptor binding"
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                "short_form": "Unattributed",
                "label": ""
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            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

258 - adiponectin binding [GO_0055100]

Binding to adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism.

Open adiponectin binding in VFB

VFB Term Json

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            "short_form": "GO_0055100",
            "label": "adiponectin binding"
        },
        "description": [
            "Binding to adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
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            "iri": "http://purl.obolibrary.org/obo/GO_0042562",
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            "short_form": "GO_0042562",
            "label": "hormone binding"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0005515",
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            "short_form": "GO_0005515",
            "label": "protein binding"
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            "DOI": ""
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    ]
}

259 - adipose tissue development [GO_0060612]

The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.

Open adipose tissue development in VFB

VFB Term Json

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            "short_form": "GO_0060612",
            "label": "adipose tissue development"
        },
        "description": [
            "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0061448",
            "types": [
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                "Class"
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            "short_form": "GO_0061448",
            "label": "connective tissue development"
        }
    ],
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            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/UBERON_0001013",
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                "short_form": "UBERON_0001013",
                "label": "adipose tissue"
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                "short_form": "GO_0048513",
                "label": "animal organ development"
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                "FlyBase": "",
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            }
        }
    ],
    "def_pubs": []
}

260 - ADP binding [GO_0043531]

Binding to ADP, adenosine 5’-diphosphate.

Open ADP binding in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0043531",
            "symbol": "",
            "types": [
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            "short_form": "GO_0043531",
            "label": "ADP binding"
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        "description": [
            "Binding to ADP, adenosine 5'-diphosphate."
        ],
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    },
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    "version": "44725ae",
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        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0032559",
            "types": [
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                "Class"
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            "short_form": "GO_0032559",
            "label": "adenyl ribonucleotide binding"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0043168",
            "types": [
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                "Class"
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            "short_form": "GO_0043168",
            "label": "anion binding"
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                "label": "adenosine diphosphate binding",
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                "DOI": ""
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                "type": ""
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    ]
}

261 - ADP catabolic process [GO_0046032]

The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5’-diphosphate.

Open ADP catabolic process in VFB

Term Information

  • ID: GO_0046032
  • Name: ADP catabolic process
  • Definition: The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5’-diphosphate.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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        "description": [
            "The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009181",
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            "short_form": "GO_0009181",
            "unique_facets": [
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            "label": "purine ribonucleoside diphosphate catabolic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009154",
            "types": [
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                "Class",
                "has_subClass"
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            "short_form": "GO_0009154",
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            "label": "purine ribonucleotide catabolic process"
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            "short_form": "GO_0046031",
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262 - ADP metabolic process [GO_0046031]

The chemical reactions and pathways involving ADP, adenosine 5’-diphosphate.

Open ADP metabolic process in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0046031",
            "symbol": "",
            "types": [
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            "short_form": "GO_0046031",
            "label": "ADP metabolic process"
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        "description": [
            "The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009150",
            "types": [
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                "Class"
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            "short_form": "GO_0009150",
            "label": "purine ribonucleotide metabolic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009179",
            "types": [
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                "Class"
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            "short_form": "GO_0009179",
            "label": "purine ribonucleoside diphosphate metabolic process"
        }
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                "type": ""
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            "FlyBase": "",
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            "DOI": ""
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    ]
}

263 - ADP phosphatase activity [GO_0043262]

Catalysis of the reaction: ADP + H2O = AMP + phosphate.

Open ADP phosphatase activity in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0043262",
            "symbol": "",
            "types": [
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                "Class"
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            "short_form": "GO_0043262",
            "label": "ADP phosphatase activity"
        },
        "description": [
            "Catalysis of the reaction: ADP + H2O = AMP + phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0017110",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0017110",
            "label": "nucleoside diphosphate phosphatase activity"
        }
    ],
    "relationships": [],
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                "type": ""
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        },
        {
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                "label": "ATP diphosphohydrolase activity",
                "type": ""
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                    "label": ""
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                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
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        },
        {
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                "scope": "has_related_synonym",
                "label": "ATP-diphosphatase activity",
                "type": ""
            },
            "pub": {
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adenosine-diphosphatase activity",
                "type": ""
            },
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                    "label": ""
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                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
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        },
        {
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                "type": ""
            },
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                    "label": ""
                },
                "FlyBase": "",
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                "DOI": ""
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        },
        {
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        },
        {
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                "FlyBase": "",
                "PubMed": "",
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        }
    ],
    "def_pubs": []
}

264 - ADP transmembrane transporter activity [GO_0015217]

Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other.

Open ADP transmembrane transporter activity in VFB

VFB Term Json

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            "short_form": "GO_0015217",
            "label": "ADP transmembrane transporter activity"
        },
        "description": [
            "Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0000295",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0000295",
            "label": "adenine nucleotide transmembrane transporter activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008514",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008514",
            "label": "Growing HA is extruded from the cell by ABCC5"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0005346",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0005346",
            "label": "purine ribonucleotide transmembrane transporter activity"
        }
    ],
    "relationships": [
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            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0015866",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0015866",
                "label": "ADP transport"
            }
        }
    ],
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                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

265 - ADP transport [GO_0015866]

The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Open ADP transport in VFB

VFB Term Json

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    "term": {
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            "symbol": "",
            "types": [
                "Entity",
                "Class"
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            "short_form": "GO_0015866",
            "label": "ADP transport"
        },
        "description": [
            "The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0051503",
            "types": [
                "Entity",
                "Class"
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            "short_form": "GO_0051503",
            "label": "adenine nucleotide transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015711",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015711",
            "label": "organic anion transport"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015868",
            "types": [
                "Entity",
                "Class"
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            "short_form": "GO_0015868",
            "label": "purine ribonucleotide transport"
        }
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

266 - ADP-ribose diphosphatase activity [GO_0047631]

Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.

Open ADP-ribose diphosphatase activity in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0047631",
            "symbol": "",
            "types": [
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            "short_form": "GO_0047631",
            "label": "ADP-ribose diphosphatase activity"
        },
        "description": [
            "Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016462",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016462",
            "label": "pyrophosphatase activity"
        }
    ],
    "relationships": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ADPR-PPase activity",
                "type": ""
            },
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                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
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                "DOI": ""
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        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adenosine diphosphoribose pyrophosphatase activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ADP-ribose phosphohydrolase activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ADP-ribose pyrophosphatase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ADPribose diphosphatase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
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                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
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        }
    ],
    "def_pubs": []
}

267 - ADP-ribosylglutamate hydrolase activity [GO_0140293]

Catalysis of the reaction: (ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + ADP-ribose.

Open ADP-ribosylglutamate hydrolase activity in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0140293",
            "symbol": "",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0140293",
            "label": "ADP-ribosylglutamate hydrolase activity"
        },
        "description": [
            "Catalysis of the reaction: (ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + ADP-ribose."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016799",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016799",
            "label": "hydrolase activity, hydrolyzing N-glycosyl compounds"
        }
    ],
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

268 - ADP-ribosylserine hydrolase activity [GO_0140292]

Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.

Open ADP-ribosylserine hydrolase activity in VFB

Term Information

  • ID: GO_0140292
  • Name: ADP-ribosylserine hydrolase activity
  • Definition: Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0140292",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
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            "short_form": "GO_0140292",
            "unique_facets": [
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            ],
            "label": "ADP-ribosylserine hydrolase activity"
        },
        "description": [
            "Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016799",
            "types": [
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                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016799",
            "unique_facets": [
                "Class"
            ],
            "label": "hydrolase activity, hydrolyzing N-glycosyl compounds"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140096",
            "types": [
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                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0140096",
            "unique_facets": [
                "Class"
            ],
            "label": "catalytic activity, acting on a protein"
        }
    ],
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                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

269 - ADP-specific glucokinase activity [GO_0043843]

Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate.

Open ADP-specific glucokinase activity in VFB

Term Information

  • ID: GO_0043843
  • Name: ADP-specific glucokinase activity
  • Definition: Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0043843",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0043843",
            "unique_facets": [
                "Class"
            ],
            "label": "ADP-specific glucokinase activity"
        },
        "description": [
            "Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016301",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016301",
            "unique_facets": [
                "Class"
            ],
            "label": "FN3KRP phosphorylates PsiAm, RibAm"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016773",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016773",
            "unique_facets": [
                "Class"
            ],
            "label": "phosphotransferase activity, alcohol group as acceptor"
        }
    ],
    "relationships": [],
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    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "ADP-dependent glucokinase activity",
                "type": ""
            },
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
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                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

270 - adrenergic receptor activity [GO_0004935]

Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex.

Open adrenergic receptor activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004935",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004935",
            "label": "adrenergic receptor activity"
        },
        "description": [
            "Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008227",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008227",
            "label": "G protein-coupled amine receptor activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0071875",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0071875",
                "label": "adrenergic receptor signaling pathway"
            }
        }
    ],
    "xrefs": [],
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        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adrenoceptor activity",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "short_form": "Unattributed",
                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
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                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

271 - adrenergic receptor signaling pathway [GO_0071875]

A G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.

Open adrenergic receptor signaling pathway in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0071875",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0071875",
            "label": "adrenergic receptor signaling pathway"
        },
        "description": [
            "A G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0007186",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0007186",
            "label": "G protein-coupled receptor signaling pathway"
        }
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                "symbol": "",
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

272 - adult behavior [GO_0030534]

Behavior in a fully developed and mature organism. See also the biological process term ‘behavior ; GO:0007610’.

Open adult behavior in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0030534",
            "symbol": "",
            "types": [
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            "short_form": "GO_0030534",
            "label": "adult behavior"
        },
        "description": [
            "Behavior in a fully developed and mature organism."
        ],
        "comment": [
            "See also the biological process term 'behavior ; GO:0007610'."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0007610",
            "types": [
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                "Class"
            ],
            "short_form": "GO_0007610",
            "label": "behavior"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0032501",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0032501",
            "label": "multicellular organismal process"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adult behavioural response to stimulus",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
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                    "types": [
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adult behavioral response to stimulus",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adult behaviour",
                "type": ""
            },
            "pub": {
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                    "short_form": "Unattributed",
                    "label": ""
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                "DOI": ""
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        }
    ],
    "def_pubs": [
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

273 - adult feeding behavior [GO_0008343]

Feeding behavior in a fully developed and mature organism. See also the biological process term ‘feeding behavior ; GO:0007631’.

Open adult feeding behavior in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008343",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008343",
            "label": "adult feeding behavior"
        },
        "description": [
            "Feeding behavior in a fully developed and mature organism."
        ],
        "comment": [
            "See also the biological process term 'feeding behavior ; GO:0007631'."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0007631",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0007631",
            "label": "feeding behavior"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0030534",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0030534",
            "label": "adult behavior"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adult feeding behaviour",
                "type": ""
            },
            "pub": {
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                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
                    "label": ""
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                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

274 - adult locomotory behavior [GO_0008344]

Locomotory behavior in a fully developed and mature organism. See also the biological process term ’locomotory behavior ; GO:0007626'.

Open adult locomotory behavior in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008344",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008344",
            "label": "adult locomotory behavior"
        },
        "description": [
            "Locomotory behavior in a fully developed and mature organism."
        ],
        "comment": [
            "See also the biological process term 'locomotory behavior ; GO:0007626'."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0030534",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0030534",
            "label": "adult behavior"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0007626",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0007626",
            "label": "locomotory behavior"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adult locomotory behaviour",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

275 - adult walking behavior [GO_0007628]

The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.

Open adult walking behavior in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0007628",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0007628",
            "label": "adult walking behavior"
        },
        "description": [
            "The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008344",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008344",
            "label": "adult locomotory behavior"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0090659",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0090659",
            "label": "walking behavior"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "adult walking behaviour",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

276 - aerobic respiration [GO_0009060]

The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.

Open aerobic respiration in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0009060",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0009060",
            "label": "aerobic respiration"
        },
        "description": [
            "The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0045333",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0045333",
            "label": "cellular respiration"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

277 - AFMID hydrolyses NFK to L-KYN [GO_0004061]

Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine.

Open AFMID hydrolyses NFK to L-KYN in VFB

Term Information

  • ID: GO_0004061
  • Name: AFMID hydrolyses NFK to L-KYN
  • Definition: Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004061",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004061",
            "unique_facets": [
                "Class"
            ],
            "label": "AFMID hydrolyses NFK to L-KYN"
        },
        "description": [
            "Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016811",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016811",
            "unique_facets": [
                "Class"
            ],
            "label": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "aryl-formylamine amidohydrolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

278 - aggressive behavior [GO_0002118]

A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual.

Open aggressive behavior in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0002118",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0002118",
            "label": "aggressive behavior"
        },
        "description": [
            "A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0007610",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0007610",
            "label": "behavior"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aggression",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

279 - aging [GO_0007568]

A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).

Open aging in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0007568",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0007568",
            "label": "aging"
        },
        "description": [
            "A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0032502",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0032502",
            "label": "developmental process"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "ageing",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

280 - ALAD condenses 2 dALAs to form PBG [GO_0004655]

Catalysis of the reaction: 2 5-aminolevulinate = 2 H2O + H+ + porphobilinogen.

Open ALAD condenses 2 dALAs to form PBG in VFB

Term Information

  • ID: GO_0004655
  • Name: ALAD condenses 2 dALAs to form PBG
  • Definition: Catalysis of the reaction: 2 5-aminolevulinate = 2 H2O + H+ + porphobilinogen.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004655",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004655",
            "unique_facets": [
                "Class"
            ],
            "label": "ALAD condenses 2 dALAs to form PBG"
        },
        "description": [
            "Catalysis of the reaction: 2 5-aminolevulinate = 2 H2O + H+ + porphobilinogen."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016836",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016836",
            "unique_facets": [
                "Class"
            ],
            "label": "hydro-lyase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aminolevulinate dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "delta-aminolevulinic acid dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "aminolevulinic dehydratase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

281 - alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate [GO_0004813]

Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).

Open alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate in VFB

Term Information

  • ID: GO_0004813
  • Name: alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate
  • Definition: Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004813",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004813",
            "unique_facets": [
                "Class"
            ],
            "label": "alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate"
        },
        "description": [
            "Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004812",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004812",
            "unique_facets": [
                "Class"
            ],
            "label": "aminoacyl-tRNA ligase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "alanyl-tRNA synthetase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "alanine translase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

282 - alanine transmembrane transporter activity [GO_0022858]

Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid.

Open alanine transmembrane transporter activity in VFB

Term Information

  • ID: GO_0022858
  • Name: alanine transmembrane transporter activity
  • Definition: Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0022858",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0022858",
            "unique_facets": [
                "Class"
            ],
            "label": "alanine transmembrane transporter activity"
        },
        "description": [
            "Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015175",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015175",
            "unique_facets": [
                "Class"
            ],
            "label": "neutral L-amino acid transmembrane transporter activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0032328",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0032328",
                "unique_facets": [
                    "Class"
                ],
                "label": "alanine transport"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

283 - alanine transport [GO_0032328]

The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Open alanine transport in VFB

Term Information

  • ID: GO_0032328
  • Name: alanine transport
  • Definition: The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0032328",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0032328",
            "unique_facets": [
                "Class"
            ],
            "label": "alanine transport"
        },
        "description": [
            "The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015804",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0015804",
            "unique_facets": [
                "Class"
            ],
            "label": "neutral amino acid transport"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "unique_facets": [
                    "pub"
                ],
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

284 - alanine-glyoxylate transaminase activity [GO_0008453]

Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine.

Open alanine-glyoxylate transaminase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008453",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008453",
            "label": "alanine-glyoxylate transaminase activity"
        },
        "description": [
            "Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008483",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008483",
            "label": "Transamination of MOB to methionine"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "alanine-glyoxylate aminotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "alanine--glyoxylate aminotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

285 - alanine-oxo-acid transaminase activity [GO_0047635]

Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid.

Open alanine-oxo-acid transaminase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0047635",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0047635",
            "label": "alanine-oxo-acid transaminase activity"
        },
        "description": [
            "Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008483",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008483",
            "label": "Transamination of MOB to methionine"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "alanine-oxo-acid aminotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "L-alanine-alpha-keto acid aminotransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

286 - ALAS condenses SUCC-CoA and Gly to form dALA [GO_0003870]

Catalysis of the reaction: glycine + H+ + succinyl-CoA = 5-aminolevulinate + CO2 + CoA.

Open ALAS condenses SUCC-CoA and Gly to form dALA in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003870",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003870",
            "label": "ALAS condenses SUCC-CoA and Gly to form dALA"
        },
        "description": [
            "Catalysis of the reaction: glycine + H+ + succinyl-CoA = 5-aminolevulinate + CO2 + CoA."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016749",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016749",
            "label": "N-succinyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "aminolevulinic acid synthetase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

287 - alcohol binding [GO_0043178]

Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group.

Open alcohol binding in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0043178",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0043178",
            "label": "alcohol binding"
        },
        "description": [
            "Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0036094",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0036094",
            "label": "small molecule binding"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

288 - alcohol dehydrogenase (NAD+) activity [GO_0004022]

Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.

Open alcohol dehydrogenase (NAD+) activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004022",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004022",
            "label": "alcohol dehydrogenase (NAD+) activity"
        },
        "description": [
            "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0018455",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0018455",
            "label": "alcohol dehydrogenase [NAD(P)+] activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "aldehyde dehydrogenase (NAD) activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aldo-keto reductase (NAD) activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "yeast alcohol dehydrogenase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

289 - alcohol dehydrogenase (NADP+) activity [GO_0008106]

Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.

Open alcohol dehydrogenase (NADP+) activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0008106",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008106",
            "label": "alcohol dehydrogenase (NADP+) activity"
        },
        "description": [
            "Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004033",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004033",
            "label": "5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "alcohol:NADP dehydrogenase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aldehyde reductase (NADPH2) activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "NADP-aldehyde reductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "aldehyde reductase (NADPH) activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

290 - alcohol dehydrogenase [NAD(P)+] activity [GO_0018455]

Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+.

Open alcohol dehydrogenase [NAD(P)+] activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0018455",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0018455",
            "label": "alcohol dehydrogenase [NAD(P)+] activity"
        },
        "description": [
            "Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016616",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016616",
            "label": "RDH11 reduces RBP2:atRAL to RBP2:atROL"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "aldehyde reductase (NADPH/NADH)",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

291 - alcohol dehydrogenase activity, zinc-dependent [GO_0004024]

Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.

Open alcohol dehydrogenase activity, zinc-dependent in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004024",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004024",
            "label": "alcohol dehydrogenase activity, zinc-dependent"
        },
        "description": [
            "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004022",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004022",
            "label": "alcohol dehydrogenase (NAD+) activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

292 - alcohol metabolic process [GO_0006066]

The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.

Open alcohol metabolic process in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0006066",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0006066",
            "label": "alcohol metabolic process"
        },
        "description": [
            "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_1901615",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1901615",
            "label": "organic hydroxy compound metabolic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0044281",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0044281",
            "label": "small molecule metabolic process"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "alcohol metabolism",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

293 - ALD3A1 oxidises 4HPCP to CXPA [GO_0004030]

Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.

Open ALD3A1 oxidises 4HPCP to CXPA in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004030",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004030",
            "label": "ALD3A1 oxidises 4HPCP to CXPA"
        },
        "description": [
            "Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016620",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016620",
            "label": "MscR reduces nitrosomycothiol to ammonia"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "aldehyde:NAD(P)+ oxidoreductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

294 - aldehyde biosynthetic process [GO_0046184]

The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O.

Open aldehyde biosynthetic process in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0046184",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0046184",
            "label": "aldehyde biosynthetic process"
        },
        "description": [
            "The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_1901576",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_1901576",
            "label": "organic substance biosynthetic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0006081",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0006081",
            "label": "cellular aldehyde metabolic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0044249",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0044249",
            "label": "cellular biosynthetic process"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aldehyde anabolism",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aldehyde biosynthesis",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aldehyde formation",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "aldehyde synthesis",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

295 - aldehyde decarbonylase activity [GO_0071771]

Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO.

Open aldehyde decarbonylase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0071771",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0071771",
            "label": "aldehyde decarbonylase activity"
        },
        "description": [
            "Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016830",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016830",
            "label": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

296 - aldehyde dehydrogenase (NAD+) activity [GO_0004029]

Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.

Open aldehyde dehydrogenase (NAD+) activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004029",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004029",
            "label": "aldehyde dehydrogenase (NAD+) activity"
        },
        "description": [
            "Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004030",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004030",
            "label": "ALD3A1 oxidises 4HPCP to CXPA"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "aldehyde:NAD+ oxidoreductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

297 - aldehyde dehydrogenase (NAD+) inhibitor activity [GO_0140631]

Binds to and stops, prevents or reduces the activity of aldehyde dehydrogenase (NAD+).

Open aldehyde dehydrogenase (NAD+) inhibitor activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0140631",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140631",
            "label": "aldehyde dehydrogenase (NAD+) inhibitor activity"
        },
        "description": [
            "Binds to and stops, prevents or reduces the activity of aldehyde dehydrogenase (NAD+)."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004857",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004857",
            "label": "enzyme inhibitor activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002212",
                "label": "negatively regulates",
                "type": "negatively_regulates"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0004029",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0004029",
                "label": "aldehyde dehydrogenase (NAD+) activity"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

298 - aldehyde oxidase activity [GO_0004031]

Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.

Open aldehyde oxidase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004031",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004031",
            "label": "aldehyde oxidase activity"
        },
        "description": [
            "Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016623",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016623",
            "label": "oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "retinal oxidase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

299 - aldehyde-lyase activity [GO_0016832]

Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.

Open aldehyde-lyase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0016832",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016832",
            "label": "aldehyde-lyase activity"
        },
        "description": [
            "Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016830",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016830",
            "label": "2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "aldolase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}

300 - ALDH4A1 oxidises L-GluSS to Glu [GO_0003842]

Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H+.

Open ALDH4A1 oxidises L-GluSS to Glu in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003842",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003842",
            "label": "ALDH4A1 oxidises L-GluSS to Glu"
        },
        "description": [
            "Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016620",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016620",
            "label": "MscR reduces nitrosomycothiol to ammonia"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "1-pyrroline dehydrogenase",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "pyrroline-5-carboxylate dehydrogenase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

301 - alditol:NADP+ 1-oxidoreductase activity [GO_0004032]

Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.

Open alditol:NADP+ 1-oxidoreductase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004032",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004032",
            "label": "alditol:NADP+ 1-oxidoreductase activity"
        },
        "description": [
            "Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008106",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008106",
            "label": "alcohol dehydrogenase (NADP+) activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "aldehyde reductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}

302 - aldose 1-epimerase activity [GO_0004034]

Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose.

Open aldose 1-epimerase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004034",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004034",
            "label": "aldose 1-epimerase activity"
        },
        "description": [
            "Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016857",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016857",
            "label": "FUOM isomerises alpha-Fuc to beta-Fuc"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "aldose mutarotase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],