pH-gated monoatomic ion channel activity [GO_0160128]

Enables the transmembrane transfer of an inorganic ion by a channel that opens in response to a change in proton concentration (pH). While the term suggest this activity may be proton-gated, the mechanism of pH-gating for transporters is by protonation of specific residues in the protein, and not by H+ binding.
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Open pH-gated monoatomic ion channel activity in VFB

Term Information

  • ID: GO_0160128
  • Name: pH-gated monoatomic ion channel activity
  • Definition: Enables the transmembrane transfer of an inorganic ion by a channel that opens in response to a change in proton concentration (pH).
  • Synonyms:
  • Type:
  • Comment: While the term suggest this activity may be proton-gated, the mechanism of pH-gating for transporters is by protonation of specific residues in the protein, and not by H+ binding.

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0160128",
            "symbol": "",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0160128",
            "unique_facets": [
                "Class"
            ],
            "label": "pH-gated monoatomic ion channel activity"
        },
        "description": [
            "Enables the transmembrane transfer of an inorganic ion by a channel that opens in response to a change in proton concentration (pH)."
        ],
        "comment": [
            "While the term suggest this activity may be proton-gated, the mechanism of pH-gating for transporters is by protonation of specific residues in the protein, and not by H+ binding."
        ]
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0015276",
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                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0015276",
            "unique_facets": [
                "Class"
            ],
            "label": "Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "proton-gated ion channel activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
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                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "acid-sensing ion channel activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "label": ""
                },
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                "PubMed": "",
                "DOI": ""
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        }
    ],
    "def_pubs": []
}