calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity [GO_0004117]

Catalysis of the reactions: 3’,5’-cyclic AMP + H2O = AMP + H+ and 3’,5’-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.
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Open calmodulin-activated dual specificity 3’,5’-cyclic-GMP, 3’,5’-cyclic-AMP phosphodiesterase activity in VFB

Term Information

  • ID: GO_0004117
  • Name: calmodulin-activated dual specificity 3’,5’-cyclic-GMP, 3’,5’-cyclic-AMP phosphodiesterase activity
  • Definition: Catalysis of the reactions: 3’,5’-cyclic AMP + H2O = AMP + H+ and 3’,5’-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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            "Catalysis of the reactions: 3',5'-cyclic AMP + H2O = AMP + H+ and 3',5'-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin."
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            "short_form": "GO_0004115",
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            "label": "p-S54-PDE4B hydrolyses cAMP"
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            "label": "PDE6 hydrolyses cGMP to GMP"
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