apical ectodermal ridge [UBERON_0004356]
Multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP].
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen apical ectodermal ridge in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/UBERON_0004356",
"symbol": "",
"types": [
"Entity",
"Anatomy",
"Class"
],
"short_form": "UBERON_0004356",
"label": "apical ectodermal ridge"
},
"description": [
"Multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/UBERON_0002050",
"types": [
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],
"short_form": "UBERON_0002050",
"label": "embryonic structure"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/CARO_0000003",
"types": [
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"short_form": "CARO_0000003",
"label": "connected anatomical structure"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0003000",
"label": "produces",
"type": "produces"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/PR_000007499",
"types": [
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"short_form": "PR_000007499",
"label": "fibroblast growth factor 8"
}
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{
"relation": {
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"label": "is part of",
"type": "part_of"
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"object": {
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"iri": "http://purl.obolibrary.org/obo/UBERON_0000924",
"types": [
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"short_form": "UBERON_0000924",
"label": "ectoderm"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
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"symbol": "",
"iri": "http://purl.obolibrary.org/obo/UBERON_0004357",
"types": [
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],
"short_form": "UBERON_0004357",
"label": "paired limb/fin bud"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002256",
"label": "developmentally induced by",
"type": "developmentally_induced_by"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/UBERON_0003104",
"types": [
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"short_form": "UBERON_0003104",
"label": "mesenchyme"
}
},
{
"relation": {
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"label": "capable of",
"type": "capable_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0010464",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0010464",
"label": "regulation of mesenchymal cell proliferation"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002215",
"label": "capable of",
"type": "capable_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0061037",
"types": [
"Entity",
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],
"short_form": "GO_0061037",
"label": "negative regulation of cartilage development"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_related_synonym",
"label": "AER",
"type": "http://purl.obolibrary.org/obo/uberon/core#LATIN"
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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