sequence_variant_causing_conservative_missense_codon_change_in_transcript [SO_1000060]

The amino acid change following from the codon change does not change the gross properties (size, charge, hydrophobicity) of the amino acid at that position. The exact rules need to be stated, a common set of rules can be derived from e.g. BLOSUM62 amino acid distance matrix.

Open sequence_variant_causing_conservative_missense_codon_change_in_transcript in VFB

Term Information

  • ID: SO_1000060
  • Name: sequence_variant_causing_conservative_missense_codon_change_in_transcript
  • Definition: The amino acid change following from the codon change does not change the gross properties (size, charge, hydrophobicity) of the amino acid at that position.
  • Synonyms:
  • Type:
  • Comment: The exact rules need to be stated, a common set of rules can be derived from e.g. BLOSUM62 amino acid distance matrix.

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/SO_1000060",
            "symbol": "",
            "types": [
                "Entity",
                "Class",
                "Deprecated"
            ],
            "short_form": "SO_1000060",
            "unique_facets": [
                "Deprecated"
            ],
            "label": "sequence_variant_causing_conservative_missense_codon_change_in_transcript"
        },
        "description": [
            "The amino acid change following from the codon change does not change the gross properties (size, charge, hydrophobicity) of the amino acid at that position."
        ],
        "comment": [
            "The exact rules need to be stated, a common set of rules can be derived from e.g. BLOSUM62 amino acid distance matrix."
        ]
    },
    "query": "Get JSON for Class",
    "version": "c58c844",
    "parents": [],
    "relationships": [],
    "related_individuals": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/IAO_0100001",
                "database_cross_reference": [],
                "label": "term replaced by",
                "type": "term_replaced_by",
                "confidence_value": ""
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/SO_0001585",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "SO_0001585",
                "unique_facets": [
                    "Class"
                ],
                "label": "conservative_missense_variant"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "sequence variant causing conservative missense codon change in transcript",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "mutation causing conservative missense codon change in transcript",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}