neuroblast NB4-3 [FBbt_00001423]

Neuroblast that delaminates at S5 and generates 2-3 neurosecretory cells that project together out of the CNS via the transverse nerve in addition to interneurons (Schmid et al., 1999). In the embryo, one of these cells can be found in each hemisegment from S1-A9 (Birkholz et al., 2013; Urbach et al., 2016). In the larva, it resumes proliferation in all thoracic segments (Lacin and Truman, 2016). The neurons that develop from this neuroblast after larval hatching form postembryonic lineage 21.

neuroblast NB4-3

ID: FBbt_00001423

Nervous system Neuroblast

Neuroblast that delaminates at S5 and generates 2-3 neurosecretory cells that project together out of the CNS via the transverse nerve in addition to interneurons (Schmid et al., 1999). In the embryo, one of these cells can be found in each hemisegment from S1-A9 (Birkholz et al., 2013; Urbach et al., 2016). In the larva, it resumes proliferation in all thoracic segments (Lacin and Truman, 2016). The neurons that develop from this neuroblast after larval hatching form postembryonic lineage 21.

Schmidt et al. (1997) describe this lineage as producing motorneurons that project into the SN. Contrarily, Schmid et al. (1999) suggest that the cells identified as motorneurons by Schmidt are actually neurosecretory cells of the TN.

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## Classification

Alternative Names

Synonym Scope Reference
lineage 21 neuroblast exact synonym Lacin and Truman, 2016
neuroblast 21 exact synonym Lacin and Truman, 2016
neuroblast NB4-3 exact synonym Lacin and Truman, 2016
lineage NB4-3 neuroblast exact synonym
NB 21 exact synonym Truman et al., 2010

Subclasses of neuroblast NB4-3 (5 total)

Thumbnail Name Tags
abdominal neuroblast NB4-3 lineage_21_NB4-3
labial neuroblast NB4-3 lineage_21_NB4-3
mandibular neuroblast NB4-3 lineage_21_NB4-3
maxillary neuroblast NB4-3 lineage_21_NB4-3
thoracic neuroblast NB4-3 lineage_21_NB4-3

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Images of neurons that develop from neuroblast NB4-3 (1112 total)

Thumbnail Name Tags
BANC_626:720575941493349831 Adult, Glutamatergic, lineage_21_NB4-3, secondary_neuron
BANC_626:720575941504593431 Adult, Glutamatergic, lineage_21_NB4-3, secondary_neuron
IN21A009_T2_L (MANC:171400) Adult, Glutamatergic, lineage_21_NB4-3, secondary_neuron
IN21A017_T3_R (MANC:12867) Adult, Cholinergic, Glutamatergic, lineage_21_NB4-3, secondary_neuron
IN21A035_T3_R (MANC:20417) Adult, Glutamatergic, lineage_21_NB4-3, secondary_neuron

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Expression patterns overlapping neuroblast NB4-3 (3 total)

Thumbnail Name Tags
P{lacZ.ry[+]}Dr[rH96] expression pattern Expression_pattern
P{HZ}svp[3] expression pattern Expression_pattern
P{lacW}hkb[s5953] expression pattern Expression_pattern

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Transgene expression in neuroblast NB4-3 (3 total)

Thumbnail Name Tags
P{lacZ.ry[+]}Dr[rH96] expression pattern Expression_pattern
P{HZ}svp[3] expression pattern Expression_pattern
P{lacW}hkb[s5953] expression pattern Expression_pattern

View all 3 results in VFB →