neuroblast NB2-3 [FBbt_00001421]

neuroblast NB2-3

ID: FBbt_00001421

Neuroblast that delaminates at S5 and produces a primary lineage, of approximately 10 neurons, in thoracic segments only (Schmid et al., 1999; Birkholz et al., 2013; Lacin and Truman, 2016; Urbach et al., 2016). These primary neurons are mainly immature motor neurons that will connect to muscle targets in the adult (Lacin and Truman, 2016). In abdominal hemisegments it can be observed at embryonic stage 17, but it either does not divide or all progeny die (Schmid et al., 1999). In the larva, it resumes proliferation in all thoracic segments and generates postembryonic lineage 15, consisting of a large number of leg motor neurons and glia (Lacin and Truman, 2016).

Originally referred to as NB1-2 by Doe (1992), this was renamed to NB2-3 by Broadus et al. (1995) to keep the names of row 2 neuroblasts consistent with their position in Schistocerca. Birkholz et al. (2015) suggest that NB2-3 does not generate a postembryonic lineage and NB3-2 generates postembryonic lineage 15, but Lacin and Truman (2016) provide lineage tracing and marker data showing that NB2-3 generates lineage 15.