non-neural ectoderm [UBERON_0005497]

Gene notes: One of the first genes to be expressed in nonneural ectoderm in amphioxus is BMP2/4 (Panopoulou et al. 1998). BMP2/4 homologues appear to have a very ancient role in distinguishing neural from nonneural ectoderm; in Drosophila as well as in amphioxus and vertebrates, BMP2/4 homologues are expressed in nonneural ectoderm and function in distinguishing neural from nonneural ectoderm (Francois & Bier, 1995 ; Sasai et al. 1995 ; Wilson & Hemmati-Brivanlou, 1995; Panopoulou et al. 1998). A change in level of BMP2/4 from very high in nonneural ectoderm to low in neural ectoderm appears to be a key factor in development of neural crest (Baker & Bronner-Fraser,1997a,1997b;Erickson&Reedy,1998;Marchantet al.1998 ;Selleck et al. 1998). [epidermal ectoderm; non-neural ectoderm; tissue; ectoderm-derived structure; material anatomical entity]

Open non-neural ectoderm in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/UBERON_0005497",
            "symbol": "",
            "types": [
                "Entity",
                "Anatomy",
                "Class"
            ],
            "short_form": "UBERON_0005497",
            "label": "non-neural ectoderm"
        },
        "description": [],
        "comment": [
            "Gene notes: One of the first genes to be expressed in nonneural ectoderm in amphioxus is BMP2/4 (Panopoulou et al. 1998). BMP2/4 homologues appear to have a very ancient role in distinguishing neural from nonneural ectoderm; in Drosophila as well as in amphioxus and vertebrates, BMP2/4 homologues are expressed in nonneural ectoderm and function in distinguishing neural from nonneural ectoderm (Francois & Bier, 1995 ; Sasai et al. 1995 ; Wilson & Hemmati-Brivanlou, 1995; Panopoulou et al. 1998). A change in level of BMP2/4 from very high in nonneural ectoderm to low in neural ectoderm appears to be a key factor in development of neural crest (Baker & Bronner-Fraser,1997a,1997b;Erickson&Reedy,1998;Marchantet al.1998 ;Selleck et al. 1998)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/UBERON_0000479",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "UBERON_0000479",
            "label": "tissue"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/CARO_0000006",
            "types": [
                "Entity",
                "Anatomy",
                "Class"
            ],
            "short_form": "CARO_0000006",
            "label": "material anatomical entity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/UBERON_0004121",
            "types": [
                "Entity",
                "Anatomy",
                "Class"
            ],
            "short_form": "UBERON_0004121",
            "label": "ectoderm-derived structure"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "epidermal ectoderm",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}