Glc6P is isomerised to I3P by ISYNA1 in the cytosol [GO_0004512]

Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.

Open Glc6P is isomerised to I3P by ISYNA1 in the cytosol in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0004512",
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            "short_form": "GO_0004512",
            "label": "Glc6P is isomerised to I3P by ISYNA1 in the cytosol"
        },
        "description": [
            "Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form."
        ],
        "comment": []
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            "iri": "http://purl.obolibrary.org/obo/GO_0016872",
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            "short_form": "GO_0016872",
            "label": "intramolecular lyase activity"
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            "synonym": {
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