Defective FMO3 does not N-oxidise TMA [GO_0004499]
Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.
Note
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VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004499",
"symbol": "",
"types": [
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"short_form": "GO_0004499",
"label": "Defective FMO3 does not N-oxidise TMA"
},
"description": [
"Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0016709",
"types": [
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],
"short_form": "GO_0016709",
"label": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
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"label": "dimethylaniline monooxygenase (N-oxide-forming) activity",
"type": ""
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},
{
"synonym": {
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"label": "methylphenyltetrahydropyridine N-monooxygenase activity",
"type": ""
},
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},
{
"synonym": {
"scope": "has_related_synonym",
"label": "FMO-II",
"type": ""
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"label": ""
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],
"def_pubs": []
}
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