Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain [GO_0050508]

Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP.

Open Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0050508",
            "symbol": "",
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                "Class"
            ],
            "short_form": "GO_0050508",
            "label": "Defective EXT1 (in EXT1:EXT2) does not transfer GlcNAc to the heparan chain"
        },
        "description": [
            "Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008375",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008375",
            "label": "POMGNT2 transfers GlcNAc to Man-DAG1"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-a-N-acetylglucosaminyltransferase activity",
                "type": ""
            },
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        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity",
                "type": ""
            },
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    "def_pubs": []
}