Cleavage of 5-hydroxyluracil by UNG glycosylase [GO_0004844]

Catalysis of the cleavage of the N-C1’ glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.
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Open Cleavage of 5-hydroxyluracil by UNG glycosylase in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0004844",
            "symbol": "",
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                "Class"
            ],
            "short_form": "GO_0004844",
            "label": "Cleavage of 5-hydroxyluracil by UNG glycosylase"
        },
        "description": [
            "Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0097506",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0097506",
            "label": "deaminated base DNA N-glycosylase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "uracil-DNA glycosylase activity",
                "type": ""
            },
            "pub": {
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
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        }
    ],
    "def_pubs": [
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}