Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) [GO_0008236]
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Note
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VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0008236",
"symbol": "",
"types": [
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"short_form": "GO_0008236",
"label": "Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)"
},
"description": [
"Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0008233",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0008233",
"label": "USP1 autocleavage"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0017171",
"types": [
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"Class"
],
"short_form": "GO_0017171",
"label": "serine hydrolase activity"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "serine protease activity",
"type": ""
},
"pub": {
"core": {
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"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"short_form": "Unattributed",
"label": ""
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"FlyBase": "",
"PubMed": "",
"DOI": ""
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],
"def_pubs": []
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