centrifugal neuron C3 [FBbt_00003744]

A centrifugal wide-field neuron with wide field arborizations in the medulla layers M1-2, M5, and M8-10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989). It forms presynapses and postsynapses in the lamina (Morante and Desplan, 2008; Rivera-Alba et al., 2011). In the medulla it is strongly presynaptic to monopolar lamina neuron L2 and columnar neuron T1, and strongly postsynaptic to L1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt}) [FBtp0015803]. The identification of dendrites was done using a UAS-Dscam (P{UAS-Dscam.exon17.1.GFP}) [FBtp0021447] reporter (Morante and Desplan, 2008). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013).

Open centrifugal neuron C3 in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00003744",
            "symbol": "C3",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "GABAergic",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00003744",
            "label": "centrifugal neuron C3"
        },
        "description": [
            "A centrifugal wide-field neuron with wide field arborizations in the medulla layers M1-2, M5, and M8-10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989). It forms presynapses and postsynapses in the lamina (Morante and Desplan, 2008; Rivera-Alba et al., 2011). In the medulla it is strongly presynaptic to monopolar lamina neuron L2 and columnar neuron T1, and strongly postsynaptic to L1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010)."
        ],
        "comment": [
            "Pre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P{UAS-HA-syt}) [FBtp0015803]. The identification of dendrites was done using a UAS-Dscam (P{UAS-Dscam.exon17.1.GFP}) [FBtp0021447] reporter (Morante and Desplan, 2008). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00110137",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00110137",
            "label": "wide-field columnar neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00003742",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00003742",
            "label": "centrifugal neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00058207",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "GABAergic",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00058207",
            "label": "adult GABAergic neuron"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003750",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003750",
                "label": "medulla layer M1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003708",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_domain"
                ],
                "short_form": "FBbt_00003708",
                "label": "lamina"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003751",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003751",
                "label": "medulla layer M2"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013009",
                "label": "sends_synaptic_output_to_cell",
                "type": "sends_synaptic_output_to_cell"
            },
            "object": {
                "symbol": "T1",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003727",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00003727",
                "label": "columnar neuron T1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013009",
                "label": "sends_synaptic_output_to_cell",
                "type": "sends_synaptic_output_to_cell"
            },
            "object": {
                "symbol": "L2",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003720",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Cholinergic",
                    "Class",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00003720",
                "label": "lamina monopolar neuron L2"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003751",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003751",
                "label": "medulla layer M2"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003750",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003750",
                "label": "medulla layer M1"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003754",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003754",
                "label": "medulla layer M5"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003760",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003760",
                "label": "medulla layer M10"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003758",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003758",
                "label": "medulla layer M8"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003759",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_subdomain"
                ],
                "short_form": "FBbt_00003759",
                "label": "medulla layer M9"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013002",
                "label": "receives synaptic input in region",
                "type": "receives_synaptic_input_in_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003708",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_domain"
                ],
                "short_form": "FBbt_00003708",
                "label": "lamina"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013008",
                "label": "receives synaptic input from neuron",
                "type": "receives_synaptic_input_from_neuron"
            },
            "object": {
                "symbol": "L1",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00003719",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Class",
                    "Glutamatergic",
                    "Nervous_system",
                    "Neuron"
                ],
                "short_form": "FBbt_00003719",
                "label": "lamina monopolar neuron L1"
            }
        }
    ],
    "xrefs": [
        {
            "link_base": "https://flybrain-ndb.virtualflybrain.org/neuronrec-",
            "site": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/FlyBrain_NDB",
                "types": [
                    "Entity",
                    "Individual",
                    "Site"
                ],
                "short_form": "FlyBrain_NDB",
                "label": "FlyBrain NeuronDB"
            },
            "is_data_source": false,
            "link_postfix": [
                ".html"
            ],
            "icon": "http://flybrain-ndb.virtualflybrain.org/NDB_title260.gif",
            "accession": "10080",
            "link_text": "centrifugal neuron C3 on FlyBrain NeuronDB",
            "homepage": "https://flybrain-ndb.virtualflybrain.org"
        }
    ],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "C3",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0054529",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0054529",
                "label": "Meinertzhagen and O'Neil, 1991, J. Comp. Neurol. 305(2): 232--263"
            },
            "FlyBase": "",
            "PubMed": "1902848",
            "DOI": "10.1002/cne.903050206"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0210635",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0210635",
                "label": "Fei et al., 2010, J. Exp. Biol. 213(10): 1717--1730"
            },
            "FlyBase": "",
            "PubMed": "20435823",
            "DOI": "10.1242/jeb.036053"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0205531",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0205531",
                "label": "Takemura et al., 2008, J. Comp. Neurol. 509(5): 493--513"
            },
            "FlyBase": "",
            "PubMed": "18537121",
            "DOI": "10.1002/cne.21757"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0049410",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0049410",
                "label": "Fischbach and Dittrich, 1989, Cell Tissue Res. 258(3): 441--475"
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0222324",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0222324",
                "label": "Takemura et al., 2013, Nature 500(7461): 175--181"
            },
            "FlyBase": "",
            "PubMed": "23925240",
            "DOI": "10.1038/nature12450"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0204652",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0204652",
                "label": "Morante and Desplan, 2008, Curr. Biol. 18(8): 553--565"
            },
            "FlyBase": "",
            "PubMed": "18403201",
            "DOI": "10.1016/j.cub.2008.02.075"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0216925",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0216925",
                "label": "Rivera-Alba et al., 2011, Curr. Biol. 21(23): 2000--2005"
            },
            "FlyBase": "",
            "PubMed": "22119527",
            "DOI": "10.1016/j.cub.2011.10.022"
        }
    ]
}