Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 [GO_0008349]
Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli.
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{
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"short_form": "GO_0008349",
"label": "Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3"
},
"description": [
"Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli."
],
"comment": []
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"query": "Get JSON for Class",
"version": "44725ae",
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"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0004674",
"types": [
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"short_form": "GO_0004674",
"label": "Activation of NLK"
}
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"relationships": [
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"iri": "http://purl.obolibrary.org/obo/GO_0000165",
"types": [
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"short_form": "GO_0000165",
"label": "MAPK cascade"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "MAPKKKK",
"type": ""
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"iri": "http://flybase.org/reports/Unattributed",
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"short_form": "Unattributed",
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}
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}
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