Active PLCG1 hydrolyses PIP2 [GO_0004435]

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H+.
Tags:

Open Active PLCG1 hydrolyses PIP2 in VFB

VFB Term Json

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            "iri": "http://purl.obolibrary.org/obo/GO_0004435",
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            "short_form": "GO_0004435",
            "label": "Active PLCG1 hydrolyses PIP2"
        },
        "description": [
            "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H+."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004629",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004629",
            "label": "PLC gamma 2-mediated PIP2 hydrolysis"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "phosphatidylinositol-4,5-bisphosphate hydrolysis",
                "type": ""
            },
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                "FlyBase": "",
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                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity",
                "type": ""
            },
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                "FlyBase": "",
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        },
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "PI-PLC activity",
                "type": ""
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    "def_pubs": []
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