MBON03 [FBbt_00100232]

MBON03

ID: FBbt_00100232

Glutamatergic neuron whose cell body is located on the superior neuropils of each hemisphere, anterior to the pars intercerebralis of the adult brain (Tanaka et al., 2008; Aso et al., 2014). The cell body fiber crosses the midline, and is sent ventrally towards the contralateral medial lobe, before making dendritic arborizations in the anterior and posterior layers of beta' lobe slice 2 (Aso et al., 2014). The main axon projects to the crepine and superior medial protocerebrum (SMP) on the same side, with a minor axon extending to the ipsilateral side (Aso et al., 2014). It has synaptic connections with protocerebral anterior medial (PAM) cluster neurons in the SMP and in the tip of the mushroom body horizontal lobe (Owald et al., 2015). It is also electrically synapsed by Kenyon cells via gap junctions (Liu et al., 2016). It is involved in the consolidation of long-term memory (Wu et al., 2017; Scaplen et al., 2020). There is one of these cells per hemisphere (Aso et al., 2014; Li et al., 2020). It develops from the larval MBON-e2 (Truman et al., 2023).

Synapsing with PAM neurons determined by GRASP (Owald et al., 2015). Blocking protein synthesis in this neuron impairs normal long-term memory formation in response to negative odor-associated learning (Wu et al., 2017). GRASP was also used to show connectivity with the DAL neurons (Wu et al., 2017).