MBON03 [FBbt_00100232]

Glutamatergic neuron whose cell body is located on the superior neuropils of each hemisphere, anterior to the pars intercerebralis of the adult brain (Tanaka et al., 2008; Aso et al., 2014. The cell body fiber crosses the midline, and is sent ventrally towards the contralateral medial lobe, before making dendritic arborizations in the anterior and posterior layers of beta’ lobe slice 2 (Aso et al., 2014. The main axon projects to the crepine and superior medial protocerebrum (SMP) on the same side, with a minor axon extending to the ipsilateral side (Aso et al., 2014. It has synaptic connections with protocerebral anterior medial (PAM) cluster neurons in the SMP and in the tip of the mushroom body horizontal lobe (Owald et al., 2015. It is also electrically synapsed by Kenyon cells via gap junctions (Liu et al., 2016. It is involved in the consolidation of long-term memory (Wu et al., 2017; Scaplen et al., 2020. There is one of these cells per hemisphere (Aso et al., 2014; Li et al., 2020. It develops from the larval MBON-e2 (Truman et al., 2023. (Li et al., 2020, Wu et al., 2017, Truman et al., 2023, Owald et al., 2015, Tanaka et al., 2008, Liu et al., 2016, Aso et al., 2014, Scaplen et al., 2020)
MBON03 MBON03 MBON03 MBON03

MBON03

ID: FBbt_00100232

Adult Glutamatergic lineage SMPad3 DAMd1 primary neuron

Glutamatergic neuron whose cell body is located on the superior neuropils of each hemisphere, anterior to the pars intercerebralis of the adult brain (Tanaka et al., 2008; Aso et al., 2014. The cell body fiber crosses the midline, and is sent ventrally towards the contralateral medial lobe, before making dendritic arborizations in the anterior and posterior layers of beta' lobe slice 2 (Aso et al., 2014. The main axon projects to the crepine and superior medial protocerebrum (SMP) on the same side, with a minor axon extending to the ipsilateral side (Aso et al., 2014. It has synaptic connections with protocerebral anterior medial (PAM) cluster neurons in the SMP and in the tip of the mushroom body horizontal lobe (Owald et al., 2015. It is also electrically synapsed by Kenyon cells via gap junctions (Liu et al., 2016. It is involved in the consolidation of long-term memory (Wu et al., 2017; Scaplen et al., 2020. There is one of these cells per hemisphere (Aso et al., 2014; Li et al., 2020. It develops from the larval MBON-e2 (Truman et al., 2023. (Li et al., 2020, Wu et al., 2017, Truman et al., 2023, Owald et al., 2015, Tanaka et al., 2008, Liu et al., 2016, Aso et al., 2014, Scaplen et al., 2020)

Synapsing with PAM neurons determined by GRASP (Owald et al., 2015. Blocking protein synthesis in this neuron impairs normal long-term memory formation in response to negative odor-associated learning (Wu et al., 2017. GRASP was also used to show connectivity with the DAL neurons (Wu et al., 2017.

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Classification

Relationships

Alternative Names

Synonym Scope Reference
MBON03 related synonym Bates et al., 2025, Berg et al., 2025, Scheffer et al., 2020, name_in_banc, Schlegel et al., 2024
M4beta' exact synonym Owald et al., 2015
MB-M4 exact synonym Tanaka et al., 2008
mushroom body medial lobe arborizing neuron 4 exact synonym
MBON03 exact synonym Li et al., 2020
MBON-beta'2mp exact synonym Aso et al., 2014
MBON-03 exact synonym Aso et al., 2014

Cross References

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Image files aligned to MBON03(B'2mp)_R:

Image files aligned to MBON03:

Image files aligned to MBON03:

Image files aligned to BANC_626:720575941532752357:

Image files aligned to MBON-B'2mp_L (FAFB:5256152):

Image files aligned to MBON-B'2mp_R (FAFB:4291899):

Image files aligned to MB-M4 of Aso 2014:

Image files aligned to MBON03(B'2mp)_R:

Image files aligned to MBON03(B'2mp)_L:

Image files aligned to MB-M4 of Aso 2014:

List all available images of MBON03 (22 total)

ThumbnailNameTags
MBON03(B'2mp)_L (MaleCNS:519373)primary_neuron, lineage_SMPad3_DAMd1, Glutamatergic, Adult
MBON03(B'2mp)_R (MaleCNS:521526)primary_neuron, lineage_SMPad3_DAMd1, Glutamatergic, Adult
MBON03(B'2mp)_R (MaleCNS:521526)primary_neuron, lineage_SMPad3_DAMd1, Glutamatergic, Adult
MBON03(B\'2mp)_R (FlyEM-HB:487925037)primary_neuron, lineage_SMPad3_DAMd1, Glutamatergic, Adult
MBON03(B\'2mp)_R (FlyEM-HB:487925037)primary_neuron, lineage_SMPad3_DAMd1, Glutamatergic, Adult

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Splits targeting MBON03 (2 total)

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Transgene expression in MBON03 (15 total)

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Downstream connectivity classes for MBON03 (302 total)

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Upstream connectivity classes for MBON03 (166 total)

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References