DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function [GO_0004862]
Binds to and stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004862",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004862",
"label": "DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function"
},
"description": [
"Binds to and stops, prevents or reduces the activity of a cAMP-dependent protein kinase."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0030291",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0030291",
"label": "protein serine/threonine kinase inhibitor activity"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0008603",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0008603",
"label": "cAMP-dependent protein kinase regulator activity"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_2000480",
"types": [
"Entity",
"Class"
],
"short_form": "GO_2000480",
"label": "negative regulation of cAMP-dependent protein kinase activity"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002212",
"label": "negatively regulates",
"type": "negatively_regulates"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0004691",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004691",
"label": "cAMP-dependent protein kinase activity"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [],
"def_pubs": [
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
]
}
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