reagent targeted gene [GENO_0000504]
A gene altered in its expression level in the context of some experiment as a result of being targeted by gene-knockdown reagent(s) such as a morpholino or RNAi. The identity of a given instance of a reagent-targeted gene is dependent on the experimental context of its knock-down - specifically what reagent was used and at what level. For example, the wild-type shha zebrafish gene targeted in epxeriment 1 by morpholino1 annd in experiment 2 by morpholino 2 represent two distinct instances of a ‘reagent-targeted gene’, despite sharing the same sequence and position.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen reagent targeted gene in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GENO_0000504",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GENO_0000504",
"label": "reagent targeted gene"
},
"description": [
"A gene altered in its expression level in the context of some experiment as a result of being targeted by gene-knockdown reagent(s) such as a morpholino or RNAi."
],
"comment": [
"The identity of a given instance of a reagent-targeted gene is dependent on the experimental context of its knock-down - specifically what reagent was used and at what level. For example, the wild-type shha zebrafish gene targeted in epxeriment 1 by morpholino1 annd in experiment 2 by morpholino 2 represent two distinct instances of a 'reagent-targeted gene', despite sharing the same sequence and position."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GENO_0000529",
"types": [
"Entity",
"Class"
],
"short_form": "GENO_0000529",
"label": "expression-variant gene"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/GENO_0000447",
"label": "is_gene_target_of",
"type": "is_gene_target_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GENO_0000533",
"types": [
"Entity",
"Class"
],
"short_form": "GENO_0000533",
"label": "gene knockdown reagent"
}
},
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/GENO_0000231",
"label": "has_proper_part",
"type": "has_proper_part"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GENO_0000534",
"types": [
"Entity",
"Class"
],
"short_form": "GENO_0000534",
"label": "reagent-targeted gene subregion"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [],
"def_pubs": [
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
]
}
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