neuroblast NB4-2 [FBbt_00001389]

Neuroblast that delaminates at S2 in the intermediate column and, in thoracic and abdominal segments, produces the RP2 motorneuron, which innervates muscles 2, 9 and 11, and the cousin of RP2 motorneuron (CoR), which innervates muscles 26, 27 and 29 (Schmid et al., 1999; Birkholz et al., 2013. It also generates around 19 interneurons (Schmid et al., 1999. In the embryo, one of these cells can be found in each hemisegment from S1-A9 (Birkholz et al., 2013; Urbach et al., 2016. In the larva, it resumes proliferation in all thoracic segments (Lacin and Truman, 2016. The neurons that develop from this neuroblast after larval hatching form postembryonic lineage 13 (Lacin and Truman, 2016. (Birkholz et al., 2013, Lacin and Truman, 2016, Schmid et al., 1999, Birkholz et al., 2015, Urbach et al., 2016)

neuroblast NB4-2

ID: FBbt_00001389

Nervous system Neuroblast

Neuroblast that delaminates at S2 in the intermediate column and, in thoracic and abdominal segments, produces the RP2 motorneuron, which innervates muscles 2, 9 and 11, and the cousin of RP2 motorneuron (CoR), which innervates muscles 26, 27 and 29 (Schmid et al., 1999; Birkholz et al., 2013. It also generates around 19 interneurons (Schmid et al., 1999. In the embryo, one of these cells can be found in each hemisegment from S1-A9 (Birkholz et al., 2013; Urbach et al., 2016. In the larva, it resumes proliferation in all thoracic segments (Lacin and Truman, 2016. The neurons that develop from this neuroblast after larval hatching form postembryonic lineage 13 (Lacin and Truman, 2016. (Birkholz et al., 2013, Lacin and Truman, 2016, Schmid et al., 1999, Birkholz et al., 2015, Urbach et al., 2016)

Birkholz et al., 2015 suggest that NB4-2 generates postembryonic lineage 7 and NB3-3 generates postembryonic lineage 13, but Lacin and Truman, 2016 provide lineage tracing and marker data showing that NB4-2 generates lineage 13.

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Classification

Alternative Names

Synonym Scope Reference
lineage 13 neuroblast exact synonym Lacin and Truman, 2016
neuroblast 13 exact synonym Lacin and Truman, 2016
neuroblast NB4-2 exact synonym Lacin and Truman, 2016
lineage NB4-2 neuroblast exact synonym
NB 13 exact synonym Truman et al., 2010

Subclasses of neuroblast NB4-2 (5 total)

ThumbnailNameTags
abdominal neuroblast NB4-2lineage_13_NB4-2
labial neuroblast NB4-2lineage_13_NB4-2
mandibular neuroblast NB4-2lineage_13_NB4-2
maxillary neuroblast NB4-2lineage_13_NB4-2
thoracic neuroblast NB4-2lineage_13_NB4-2

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References