neuroblast NB4-2 [FBbt_00001389]

Neuroblast NB4-2 delaminates at S2 in the intermediate column and produces the well characterized RP2 motorneuron (FBbt:00001453), which innervates muscles 2, 9 and 11. It also produces the Cousins if RP2 motorneurons (CoR), which generate the entirety of the SNc, innervating muscles 26, 27 and 29. It also generates local interneurons and, in a small number of cases, an epidermal subclone. This neuroblast resumes proliferation in the larva and generates postembryonic lineage 13 (Lacin and Truman, 2016). Birkholz et al. (2015) suggest that NB4-2 generates postembryonic lineage 7 and NB3-3 generates postembryonic lineage 13, but Lacin and Truman (2016) provide lineage tracing and marker data showing that NB4-2 generates lineage 13.

Open neuroblast NB4-2 in VFB

VFB Term Json

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            "short_form": "FBbt_00001389",
            "label": "neuroblast NB4-2"
        },
        "description": [
            "Neuroblast NB4-2 delaminates at S2 in the intermediate column and produces the well characterized RP2 motorneuron (FBbt:00001453), which innervates muscles 2, 9 and 11. It also produces the Cousins if RP2 motorneurons (CoR), which generate the entirety of the SNc, innervating muscles 26, 27 and 29. It also generates local interneurons and, in a small number of cases, an epidermal subclone. This neuroblast resumes proliferation in the larva and generates postembryonic lineage 13 (Lacin and Truman, 2016)."
        ],
        "comment": [
            "Birkholz et al. (2015) suggest that NB4-2 generates postembryonic lineage 7 and NB3-3 generates postembryonic lineage 13, but Lacin and Truman (2016) provide lineage tracing and marker data showing that NB4-2 generates lineage 13."
        ]
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