adult doublesex aDN neuron [FBbt_00047354]

Doublesex-expressing neuron of the adult that has its soma in the anterodorsal region of the superior protocerebrum (Lee et al., 2002). There are two of these cells per hemisphere in both males and females (Nojima et al., 2021). In both sexes, their neurites are all ipsilateral, with a medial arbor in the superior medial protocerebrum containing mainly presynaptic sites (Nojima et al., 2021). Lateral arborization, containing mainly postsynaptic sites, is sexually-dimorphic (Nojima et al., 2021). These neurons are glutamatergic (Pavlou et al., 2016). Lee et al. (2002) and Robinett et al. (2010) state that they do not see aDN in the female, but Rideout et al., 2010 and Pavlou et al., 2016 show that they are present in the female. These neurons do not express fruitless (Pavlou et al., 2016).

Open adult doublesex aDN neuron in VFB

Example Images

adult doublesex aDN neuron adult doublesex aDN neuron

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00047354",
            "symbol": "",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Glutamatergic",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00047354",
            "label": "adult doublesex aDN neuron"
        },
        "description": [
            "Doublesex-expressing neuron of the adult that has its soma in the anterodorsal region of the superior protocerebrum (Lee et al., 2002). There are two of these cells per hemisphere in both males and females (Nojima et al., 2021). In both sexes, their neurites are all ipsilateral, with a medial arbor in the superior medial protocerebrum containing mainly presynaptic sites (Nojima et al., 2021). Lateral arborization, containing mainly postsynaptic sites, is sexually-dimorphic (Nojima et al., 2021). These neurons are glutamatergic (Pavlou et al., 2016)."
        ],
        "comment": [
            "Lee et al. (2002) and Robinett et al. (2010) state that they do not see aDN in the female, but Rideout et al., 2010 and Pavlou et al., 2016 show that they are present in the female. These neurons do not express fruitless (Pavlou et al., 2016)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00051203",
            "types": [
                "Entity",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00051203",
            "label": "sexually-dimorphic neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00058208",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Glutamatergic",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00058208",
            "label": "adult glutamatergic neuron"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/FBbt_00047347",
            "types": [
                "Entity",
                "Adult",
                "Anatomy",
                "Cell",
                "Class",
                "Nervous_system",
                "Neuron"
            ],
            "short_form": "FBbt_00047347",
            "label": "adult doublesex neuron"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0013003",
                "label": "sends_synaptic_output_to_region",
                "type": "sends_synaptic_output_to_region"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00007055",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system",
                    "Synaptic_neuropil",
                    "Synaptic_neuropil_domain"
                ],
                "short_form": "FBbt_00007055",
                "label": "superior medial protocerebrum"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002100",
                "label": "has soma location",
                "type": "has_soma_location"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/FBbt_00100308",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Class",
                    "Nervous_system"
                ],
                "short_form": "FBbt_00100308",
                "label": "adult superior brain cell body rind"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0000053",
                "label": "bearer of",
                "type": "bearer_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/PATO_0000634",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "PATO_0000634",
                "label": "unilateral"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [
        {
            "anatomy": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/VFB_001014u7",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Expression_pattern_fragment",
                    "Glutamatergic",
                    "Individual",
                    "Nervous_system",
                    "Neuron",
                    "has_image"
                ],
                "short_form": "VFB_001014u7",
                "label": "Female_aDN"
            },
            "channel_image": {
                "image": {
                    "template_channel": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFBc_00101567",
                        "types": [
                            "Entity",
                            "Individual",
                            "Template"
                        ],
                        "short_form": "VFBc_00101567",
                        "label": "JRC2018Unisex_c"
                    },
                    "index": [],
                    "template_anatomy": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFB_00101567",
                        "types": [
                            "Entity",
                            "Adult",
                            "Anatomy",
                            "Individual",
                            "Nervous_system",
                            "Template",
                            "has_image"
                        ],
                        "short_form": "VFB_00101567",
                        "label": "JRC2018Unisex"
                    },
                    "image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/14u7/VFB_00101567/"
                },
                "channel": {
                    "symbol": "",
                    "iri": "http://virtualflybrain.org/reports/VFBc_001014u7",
                    "types": [
                        "Entity",
                        "Individual"
                    ],
                    "short_form": "VFBc_001014u7",
                    "label": "Female_aDN_c"
                },
                "imaging_technique": {
                    "symbol": "Confocal",
                    "iri": "http://purl.obolibrary.org/obo/FBbi_00000251",
                    "types": [
                        "Entity",
                        "Class"
                    ],
                    "short_form": "FBbi_00000251",
                    "label": "confocal microscopy"
                }
            }
        },
        {
            "anatomy": {
                "symbol": "",
                "iri": "http://virtualflybrain.org/reports/VFB_001014u6",
                "types": [
                    "Entity",
                    "Adult",
                    "Anatomy",
                    "Cell",
                    "Expression_pattern_fragment",
                    "Glutamatergic",
                    "Individual",
                    "Nervous_system",
                    "Neuron",
                    "has_image"
                ],
                "short_form": "VFB_001014u6",
                "label": "Male_aDN"
            },
            "channel_image": {
                "image": {
                    "template_channel": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFBc_00101567",
                        "types": [
                            "Entity",
                            "Individual",
                            "Template"
                        ],
                        "short_form": "VFBc_00101567",
                        "label": "JRC2018Unisex_c"
                    },
                    "index": [],
                    "template_anatomy": {
                        "symbol": "",
                        "iri": "http://virtualflybrain.org/reports/VFB_00101567",
                        "types": [
                            "Entity",
                            "Adult",
                            "Anatomy",
                            "Individual",
                            "Nervous_system",
                            "Template",
                            "has_image"
                        ],
                        "short_form": "VFB_00101567",
                        "label": "JRC2018Unisex"
                    },
                    "image_folder": "http://www.virtualflybrain.org/data/VFB/i/0010/14u6/VFB_00101567/"
                },
                "channel": {
                    "symbol": "",
                    "iri": "http://virtualflybrain.org/reports/VFBc_001014u6",
                    "types": [
                        "Entity",
                        "Individual"
                    ],
                    "short_form": "VFBc_001014u6",
                    "label": "Male_aDN_c"
                },
                "imaging_technique": {
                    "symbol": "Confocal",
                    "iri": "http://purl.obolibrary.org/obo/FBbi_00000251",
                    "types": [
                        "Entity",
                        "Class"
                    ],
                    "short_form": "FBbi_00000251",
                    "label": "confocal microscopy"
                }
            }
        }
    ],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "doublesex-expressing anterior-Dorsal Neuron",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0159058",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0159058",
                    "label": "Lee et al., 2002, J. Neurogenet. 16(4): 229--248"
                },
                "FlyBase": "",
                "PubMed": "12745633",
                "DOI": "10.1080/01677060216292"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dsx-aDN",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0159058",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0159058",
                    "label": "Lee et al., 2002, J. Neurogenet. 16(4): 229--248"
                },
                "FlyBase": "",
                "PubMed": "12745633",
                "DOI": "10.1080/01677060216292"
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dsx-expressing anterior-Dorsal Neuron",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/FBrf0159058",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "FBrf0159058",
                    "label": "Lee et al., 2002, J. Neurogenet. 16(4): 229--248"
                },
                "FlyBase": "",
                "PubMed": "12745633",
                "DOI": "10.1080/01677060216292"
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0210397",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0210397",
                "label": "Rideout et al., 2010, Nat. Neurosci. 13(4): 458--466"
            },
            "FlyBase": "",
            "PubMed": "20305646",
            "DOI": "10.1038/nn.2515"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0159058",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0159058",
                "label": "Lee et al., 2002, J. Neurogenet. 16(4): 229--248"
            },
            "FlyBase": "",
            "PubMed": "12745633",
            "DOI": "10.1080/01677060216292"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0234085",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0234085",
                "label": "Pavlou et al., 2016, eLife 5: e20713"
            },
            "FlyBase": "",
            "PubMed": "27855059",
            "DOI": "10.7554/eLife.20713"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0210735",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0210735",
                "label": "Robinett et al., 2010, PLoS Biol. 8(5): e1000365"
            },
            "FlyBase": "",
            "PubMed": "20454565",
            "DOI": "10.1371/journal.pbio.1000365"
        },
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBrf0248430",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "FBrf0248430",
                "label": "Nojima et al., 2021, Curr. Biol. 31(6): 1175--1191.e6"
            },
            "FlyBase": "FBrf0248430",
            "PubMed": "33508219",
            "DOI": "10.1016/j.cub.2020.12.047"
        }
    ]
}