perineurial glial sheath [FBbt_00007089]

The outermost cellular layer of the nervous system, probably of mesodermal origin (Hartenstein and Jan, 1992). This layer consists of glial cells, which participate in nutrient uptake and establish a first diffusion barrier (Limmer et al., 2014). Evidence of mesodermal origin comes from the observation that embryos lacking mesoderm lack this cell layer and the overlying neural lamella (Edwards et al., 1993).

Open perineurial glial sheath in VFB

VFB Term Json

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        "core": {
            "iri": "http://purl.obolibrary.org/obo/FBbt_00007089",
            "symbol": "",
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            ],
            "short_form": "FBbt_00007089",
            "label": "perineurial glial sheath"
        },
        "description": [
            "The outermost cellular layer of the nervous system, probably of mesodermal origin (Hartenstein and Jan, 1992). This layer consists of glial cells, which participate in nutrient uptake and establish a first diffusion barrier (Limmer et al., 2014)."
        ],
        "comment": [
            "Evidence of mesodermal origin comes from the observation that embryos lacking mesoderm lack this cell layer and the overlying neural lamella (Edwards et al., 1993)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
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            "short_form": "FBbt_00007003",
            "label": "portion of tissue"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/CARO_0000003",
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            "short_form": "CARO_0000003",
            "label": "connected anatomical structure"
        }
    ],
    "relationships": [
        {
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                "label": "is part of",
                "type": "part_of"
            },
            "object": {
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                ],
                "short_form": "FBbt_00007090",
                "label": "perineurium"
            }
        },
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002371",
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                "type": "attached_to"
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                ],
                "short_form": "FBbt_00007091",
                "label": "subperineurial glial sheath"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
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        },
        {
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                "label": "apical glial cell",
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            "pub": {
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                    "short_form": "FBrf0206543",
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                "PubMed": "19091965",
                "DOI": "10.1523/JNEUROSCI.4844-08.2008"
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        },
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        },
        {
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                    ],
                    "short_form": "FBrf0214261",
                    "label": "Hartenstein, 2011, Glia 59(9): 1237--1252"
                },
                "FlyBase": "",
                "PubMed": "21438012",
                "DOI": "10.1002/glia.21162"
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        }
    ],
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                "label": "Edwards et al., 1993, J. Comp. Neurol. 333(2): 301--308"
            },
            "FlyBase": "",
            "PubMed": "8345109",
            "DOI": "10.1002/cne.903330214"
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}