type II neuroblast FBbt_00100533

type II neuroblast

ID: FBbt_00100533

Neuroblast that divides asymmetrically regenerate itself and produce a smaller intermediate neural progenitor (INP), which can produce multiple ganglion mother cells (Boone and Doe, 2008, Viktorin et al., 2011; Ren et al., 2016. Each type II neuroblast can produce multiple INPs, leading to the generation of multiple sublineages and typically more progeny than type I neuroblasts (Ren et al., 2016. It arises relatively late during embryonic development, delaminating from the dorsal cephalic neuroectoderm during stages 11-15 (Walsh and Doe, 2017. These cells and any existing INPs enter quiescence shortly before larval hatching (Walsh and Doe, 2017. There are eight type II neuroblasts per hemisphere, all belonging to the brain (Walsh and Doe, 2017. (Viktorin et al., 2011, Boone and Doe, 2008, Ren et al., 2016, Bello et al., 2008, Weng et al., 2010, Walsh and Doe, 2017, Maurange et al., 2008)

Bayraktar et al. (2010) show that type II neuroblasts can be distinguished from type I neuroblasts as being Deadpan-positive, but Prospero- and Asense-negative. Walsh and Doe, 2017 also use pointed as a positive marker. Arise later than NBs of embryonic NB map in Urbach and Technau (2003) - FBrf0173125 (Walsh and Doe, 2017.