PS221 [FBbt_20001976]

Adult brain-intrinsic neuron of the PS221 group, with its soma in the brain, posterior to the inferior bridge (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the PSp2 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral inferior posterior slope and the ipsilateral superior posterior slope (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral inferior posterior slope, the gnathal ganglia and the ipsilateral superior posterior slope (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 7 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).
PS221 PS221 PS221 PS221

PS221

ID: FBbt_20001976

Adult Cholinergic lineage PSp2 CM5

Adult brain-intrinsic neuron of the PS221 group, with its soma in the brain, posterior to the inferior bridge (Schlegel et al., 2024; Dorkenwald et al., 2024). It belongs to the PSp2 hemilineage (Schlegel et al., 2024; Dorkenwald et al., 2024). It has postsynapses in the ipsilateral inferior posterior slope and the ipsilateral superior posterior slope (Schlegel et al., 2024; Dorkenwald et al., 2024). It has presynapses in the ipsilateral inferior posterior slope, the gnathal ganglia and the ipsilateral superior posterior slope (Schlegel et al., 2024; Dorkenwald et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 7 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024).

Uncharacterized putative cell type based on Hemibrain data (Scheffer et al., 2020) and updated using FlyWire (FAFB) data (Dorkenwald et al., 2024; Schlegel et al., 2024). Soma locations are based on the closest annotated neuropil region. Pre- or post-synapse locations are the fewest regions that collectively contain at least 80 percent of all pre- or post-synapses of these neurons in FlyWire. Neurotransmitter predictions are from Eckstein et al. (2024). Other annotations are based on annotations in FlyWire and are available in the supplemental material of Schlegel et al. (2024).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
PS221 exact synonym Scheffer et al., 2020
PS221 exact synonym Schlegel et al., 2024
PS221 exact synonym Bates et al., 2025
PS221 exact synonym Berg et al., 2025
PS221 exact synonym

List all available images of PS221 (25 total)

Thumbnail Name Tags
PS221_L (MaleCNS:29327) lineage_PSp2_CM5, Adult, Cholinergic
PS221_L (MaleCNS:32251) lineage_PSp2_CM5, Adult, Cholinergic
PS221_R (MaleCNS:22277) lineage_PSp2_CM5, Adult, Cholinergic
PS221_R (MaleCNS:515720) lineage_PSp2_CM5, Adult, Cholinergic
PS221_R (MaleCNS:530123) lineage_PSp2_CM5, Adult, Cholinergic

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Downstream connectivity classes for PS221 (137 total)

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Upstream connectivity classes for PS221 (195 total)

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