OA-AL2b1 [FBbt_00110146]

Octopaminergic neuron of the AL2 cluster which innervates the ipsilateral and contralateral lobula (Busch et al., 2009). It has greater innervation of the contralateral lobula, with mixed pre- and post- synapses in layers 5 and 6, spanning around 100 columns (Nern et al., 2025). It has its soma ventral-medial to the antennal lobe and is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). Its main process extends posteriodorsally from the soma, close to the esophageal foramen, then bifurcates in the posterior brain, projecting to both optic lobes (Busch et al., 2009; Dorkenwald et al., 2024; Schlegel et al., 2024; Nern et al., 2025). In the central brain, it receives input in the superior posterior slope, posterior lateral protocerebrum and cantle (Schlegel et al., 2024; Dorkenwald et al., 2024). There is one of these cells per hemisphere (Nern et al., 2025).
OA-AL2b1 OA-AL2b1 OA-AL2b1 OA-AL2b1

OA-AL2b1

ID: FBbt_00110146

Adult Nervous system Octopaminergic Visual system primary neuron

Octopaminergic neuron of the AL2 cluster which innervates the ipsilateral and contralateral lobula (Busch et al., 2009). It has greater innervation of the contralateral lobula, with mixed pre- and post- synapses in layers 5 and 6, spanning around 100 columns (Nern et al., 2025). It has its soma ventral-medial to the antennal lobe and is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). Its main process extends posteriodorsally from the soma, close to the esophageal foramen, then bifurcates in the posterior brain, projecting to both optic lobes (Busch et al., 2009; Dorkenwald et al., 2024; Schlegel et al., 2024; Nern et al., 2025). In the central brain, it receives input in the superior posterior slope, posterior lateral protocerebrum and cantle (Schlegel et al., 2024; Dorkenwald et al., 2024). There is one of these cells per hemisphere (Nern et al., 2025).

The neurotransmitter was assessed by immunostaining with an anti-octopamine (OA) antibody in cells labelled with tdc2-GAL4 (FBti0101786) and NP7088-GAL4 (Busch et al., 2009). Mapped to EM data in Nern et al. (2025) and Schlegel et al. (2024).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
LoVCLo3 exact synonym Berg et al., 2025
OA-AL2b1 exact synonym Schlegel et al., 2024
OA-AL2b1 exact synonym Bates et al., 2025
OA-AL2b1 exact synonym Busch et al., 2009
LoVCLo3 exact synonym Nern et al., 2025
adult posterior lateral protocerebrum neuron 244 exact synonym
PLP244 exact synonym Scheffer et al., 2020

List all available images of OA-AL2b1 (10 total)

Thumbnail Name Tags
LoVCLo3_L (MaleCNS:10432) Nervous_system, primary_neuron, Visual_system, Adult, Octopaminergic
LoVCLo3_R (MaleCNS:10100) Nervous_system, primary_neuron, Visual_system, Adult, Octopaminergic
PLP244(SCB010)_L Nervous_system, primary_neuron, Visual_system, Adult, Octopaminergic
PLP244(SCB010)_L Nervous_system, primary_neuron, Visual_system, Adult, Octopaminergic
PLP244(SCB010)_L Nervous_system, primary_neuron, Visual_system, Adult, Octopaminergic

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Downstream connectivity classes for OA-AL2b1 (552 total)

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Upstream connectivity classes for OA-AL2b1 (416 total)

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