N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity [GO_0050509]

Catalysis of the reaction: 3-O-{alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-{(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + H+ + UDP.
Tags:

N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity

ID: GO_0050509

Class

Catalysis of the reaction: 3-O-{alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-{(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + H+ + UDP.

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Classification

Alternative Names

Synonym Scope Reference
heparan glucuronyltransferase II activity related synonym 2.4.1.225
UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase activity related synonym 2.4.1.225
N-acetylglucosaminylproteoglycan beta-1,4-glucuronyltransferase activity related synonym 2.4.1.225
N-acetylglucosaminyl-proteoglycan 4-b-glucuronosyltransferase activity exact synonym

References