miRNA-mediated gene silencing by mRNA destabilization GO_0035279
miRNA-mediated gene silencing by mRNA destabilization
ID: GO_0035279
Class
An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.
Open in VFB 3D Browser →Classification
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| deadenylation involved in gene silencing by miRNA | related synonym | |
| miRNA-mediated gene silencing by mRNA deadenylation | related synonym | |
| gene silencing by mRNA cleavage | broad synonym | |
| mRNA destabilization-mediated gene silencing by miRNA | exact synonym | |
| gene silencing by miRNA, mRNA cleavage | exact synonym | mah |
| miRNA-mediated gene silencing, mRNA cleavage | exact synonym | dph |
| mRNA cleavage involved in gene silencing by microRNA | exact synonym | pr |
| mRNA cleavage involved in gene silencing by miRNA | exact synonym | |
| mRNA deadenylation-mediated gene silencing by miRNA | related synonym |