metalloendopeptidase activity [GO_0004222]

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

metalloendopeptidase activity

ID: GO_0004222

Class

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

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Classification

Alternative Names

Synonym Scope Reference
metalloendoprotease activity narrow synonym mah
metalloendoproteinase activity narrow synonym mah

References