MAP kinase activity [GO_0004707]

Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
Tags:

MAP kinase activity

ID: GO_0004707

Class

Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.

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Classification

Relationships

Alternative Names

Synonym Scope Reference
MAPK related synonym 2.7.11.24
ERK related synonym 2.7.11.24
ERK2 related synonym
mitogen-activated protein kinase activity related synonym 2.7.11.24
ATP:protein phosphotransferase (MAPKK-activated) activity related synonym 2.7.11.24
MAP kinase 2 activity narrow synonym
extracellular signal-regulated kinase activity narrow synonym 2.7.11.24
MBP kinase II activity narrow synonym 2.7.11.24
myelin basic protein kinase activity narrow synonym 2.7.11.24
SAPK narrow synonym
MAP kinase 1 activity narrow synonym
stress-activated kinase activity narrow synonym
SAP kinase activity narrow synonym
stress-activated protein kinase activity narrow synonym
MBP kinase I activity narrow synonym 2.7.11.24
ERK1 exact synonym
mitogen activated kinase activity exact synonym

References