lipoate synthase activity [GO_0016992]
Catalysis of the reaction: [[Fe-S] cluster scaffold protein carrying a second [4Fe-4S]2+ cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H+ = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe3+ + 2 hydrogen sulfide + 2 5’-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin].
lipoate synthase activity
ID: GO_0016992
Class
Catalysis of the reaction: [[Fe-S] cluster scaffold protein carrying a second [4Fe-4S]2+ cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H+ = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe3+ + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin].
Open in VFB 3D Browser →Classification
Relationships
- is part of: lipoate biosynthetic process
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity | related synonym | 2.8.1.8 |
| LS | related synonym | 2.8.1.8 |
| LipA | related synonym | 2.8.1.8 |
| protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity | related synonym | 2.8.1.8 |
| lipoyl synthase activity | related synonym | 2.8.1.8 |
| lipoic acid synthase | exact synonym | dph |
References
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