larval VUM motor neuron [FBbt_00110181]

larval VUM motor neuron

ID: FBbt_00110181

Motor neuron that develops from a VUM precursor (midline precursors 4-6) (Crews, 2019. There are three of these cells per segment (Schmid et al., 1999. They are modulatory motor neurons; in A1-7, one VUM motor neuron innervates the dorsal muscles, one innervates the ventral muscles, and one innervates the lateral muscles. These neurons are all octopaminergic and tyraminergic (Stocker et al., 2018. (Kearney et al., 2004, Crews, 2019, Stocker et al., 2018, Bossing and Technau, 1994, Schmid et al., 1999)

Wheeler et al. (2006) - FBrf0195284 showed expression of the vesicular glutamate transporter (vGlut), tyramine beta-hydroxylase (Tbh) and the vesicular monoamine transporter (Vmat). Vomel and Wegener (2008) used Tdc2-GAL4 and anti-Tbh. Selcho et al. (2012) used Tdc2-GAL4, validated with anti-Tbh, anti-p-tyramine and anti-conjugated octopamine. Stocker et al., 2018 used octopamine and tyramine antibodies. VUM neurons are found in thoracic and abdominal segments (Schmid et al., 1999. Seem to be the only type II MN to innervate body wall (hypodermal) muscles.