larval Saaghi 1 neuron FBbt_00111659

larval Saaghi 1 neuron

ID: FBbt_00111659

Larval GABAergic premotor neuron (Zarin et al., 2019 that is relatively late-born in the NB5-2 Notch ON primary hemilineage (Mark et al., 2021. Its primary neurite extends into the neuromere forming one arbor that extends anteriorly. One neurite crosses the midline and forms a terminal arbor that extends in a circular manner. It outputs to contralateral ventral and dorsal motorneurons. There is of these one neurons per hemisegment. (Heckscher et al., 2015, Mark et al., 2021)

These neurons were identified in two EM reconstructions: one of the full CNS of a 6h old first instar larva, and another of abdominal segment 3 of a 12-24h old first instar larva. Only bilateral connections are reported. The number of identified input synapses in A1 was the following (number in brackets left/right): from A08e1 (2/3), from A08e2 (2/6), from A08e3 (4/5). The number of identified output synapses in A1 was the following (number in brackets left/right): to ventral motoneurons (33/15), to lateral motoneurons (2/8), to dorsal motoneurons (34/37). It is still not known if the pattern of connections is the same in the other abdominal segments (Heckscher et al., 2015.