large conductance calcium-activated potassium channel activity GO_0060072
large conductance calcium-activated potassium channel activity
ID: GO_0060072
Class
Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
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Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| large conductance KCa channel activity | exact synonym | |
| BK calcium-activated potassium channel activity | exact synonym | |
| BK KCa channel activity | exact synonym | |
| BK channel activity | related synonym |