insulin secreting cell of pars intercerebralis FBbt_00004011
insulin secreting cell of pars intercerebralis
ID: FBbt_00004011
Insulin-producing neuron with a cell body in the pars intercerebralis. These cells coexpress the genes Insulin-like peptide (Ilp) 2, Ilp3 and Ilp5 (Reinhard et al., 2024. There are approximately 7-9 of these cells per hemisphere and they fasciculate with the nervus corporis cardiaci (McKim et al., 2024). (Enell et al., 2010, Broughton et al., 2005, Cao et al., 2014, Siegmund and Korge, 2001, Cao and Brown, 2001, de Velasco et al., 2007, Reinhard et al., 2024, Rulifson et al., 2002, Ikeya et al., 2002)
Insulin-producing cells are found amongst the median neurosecretory cells, but not all mNSCs are IPCs (FBrf0212696), despite misleading phrasing in some articles (e.g. FBrf0184236).
Open in VFB 3D Browser →Classification
- efferent neuron
- neurosecretory cell of pars intercerebralis
- peptide hormone secreting cell
- peptidergic neuron
Relationships
- expresses: Ilp2
- fasciculates with: nervus corporis cardiaci
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| dorsomedial neurosecretory cell | broad synonym | |
| insulin producing cell of brain | exact synonym | |
| m-NSC DILP | exact synonym | Reinhard et al., 2024 |
| IPC | broad synonym |
Downloads
Image files aligned to IPC 4 right (L1EM:15202263):
Image files aligned to IPC 1 right (L1EM:13535380):
Image files aligned to IPC 3 left (L1EM:12634154):
Image files aligned to _IPC 2 (L1EM:10459723):
Image files aligned to IPC 4 left (L1EM:4453485):
Image files aligned to IPC 5 left (L1EM:3281684):
Image files aligned to IPC 7 left (L1EM:3046503):
Image files aligned to IPC 6 right (L1EM:2357110):
Image files aligned to _IPC 2 (L1EM:2852273):
Image files aligned to IPC 7 right (L1EM:2355126):
List all available images of insulin secreting cell of pars intercerebralis (131 total)
| Thumbnail | Name | Tags |
|---|---|---|
 | IPC_L (MaleCNS:13712) | Peptidergic, Nervous_system, Adult |
 | IPC_L (MaleCNS:13712) | Peptidergic, Nervous_system, Adult |
 | IPC_R (MaleCNS:12400) | Nervous_system, Peptidergic, Adult |
 | IPC_R (MaleCNS:12400) | Nervous_system, Peptidergic, Adult |
 | IPC_R (MaleCNS:555768) | Nervous_system, Peptidergic, Adult |
Subclasses of insulin secreting cell of pars intercerebralis (4 total)
| Thumbnail | Name | Tags |
|---|---|---|
| adult Drosulfakinin neuron of pars intercerebralis | Adult, Nervous_system, Peptidergic | |
 | adult insulin secreting cell of pars intercerebralis | Adult, Nervous_system, Peptidergic |
| larval Drosulfakinin neuron of pars intercerebralis | Larva, Nervous_system, Peptidergic | |
| larval insulin secreting cell of pars intercerebralis | Larva, Nervous_system, Peptidergic |
scRNAseq data for insulin secreting cell of pars intercerebralis (7 total)
| Thumbnail | Name | Tags |
|---|---|---|
| scRNAseq_2018_Davie_FULL_seq_clustering_IPC_cells | Adult, Cluster, Nervous_system | |
| scRNAseq_2022_FCA_MALE_FULL_seq_clustering_insulin_secreting_cells | Adult, Cluster, Nervous_system | |
| scRNAseq_2022_FCA_MALE_IPC_seq_clustering_insulin_secreting_cells | Adult, Cluster, Nervous_system | |
| scRNAseq_2022_FCA_FEMALE_FULL_seq_clustering_insulin_secreting_cells | Adult, Cluster, Nervous_system | |
| scRNAseq_2022_FCA_FEMALE_IPC_seq_clustering_insulin_secreting_cells | Adult, Cluster, Nervous_system |
Transgene expression in insulin secreting cell of pars intercerebralis (15 total)
| Thumbnail | Name | Tags |
|---|---|---|
 | P{GMR19B09-lexA} expression pattern | Expression_pattern |
 | P{GMR65C11-GAL4} expression pattern | Expression_pattern |
 | P{GMR64H09-GAL4} expression pattern | Expression_pattern |
 | P{GMR19B09-GAL4} expression pattern | Expression_pattern |
 | PBac{681.P.FSVS-1}CG9336[CPTI001654] expression pattern | Expression_pattern |
Downstream connectivity classes for insulin secreting cell of pars intercerebralis (84 total)
| Thumbnail | Name | Tags |
|---|---|---|
Upstream connectivity classes for insulin secreting cell of pars intercerebralis (635 total)
| Thumbnail | Name | Tags |
|---|---|---|