insulator [SO_0000627]

A regulatory region that 1) when located between a CRM and a gene’s promoter prevents the CRM from modulating that genes expression and 2) acts as a chromatin boundary element or barrier that can block the encroachment of condensed chromatin from an adjacent region.

insulator

ID: SO_0000627

Class

A regulatory region that 1) when located between a CRM and a gene's promoter prevents the CRM from modulating that genes expression and 2) acts as a chromatin boundary element or barrier that can block the encroachment of condensed chromatin from an adjacent region.

moved from is_a: SO:0001055 transcriptional_cis_regulatory_region as per request from GREEKC initiative in August 2020.

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Classification

Alternative Names

Synonym Scope Reference
INSDC_feature:regulatory broad synonym
INSDC_qualifier:insulator exact synonym
insulator element exact synonym