G protein-coupled receptor signaling pathway GO_0007186
G protein-coupled receptor signaling pathway
ID: GO_0007186
Class
The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
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Relationships
- has part: G-protein coupled receptor activity
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| G-protein coupled receptor signaling pathway via GPCR dimer | narrow synonym | bf |
| dimeric G-protein coupled receptor signaling pathway | narrow synonym | |
| dimeric G-protein coupled receptor signalling pathway | narrow synonym | mah |
| G-protein coupled receptor protein signal transduction | exact synonym | |
| G protein coupled receptor protein signaling pathway | exact synonym | |
| G protein coupled receptor protein signalling pathway | exact synonym | |
| G-protein coupled receptor signalling pathway | exact synonym | |
| G-protein-coupled receptor protein signalling pathway | exact synonym | |
| GPCR signaling pathway | exact synonym | |
| GPCR signalling pathway | exact synonym | |
| G-protein coupled receptor protein signaling pathway | exact synonym | bf |